Results 21 to 30 of about 154,170 (305)

Transcriptomic landscapes of effective and failed liver regeneration in humans

JHEP Reports, 2023
Background & Aims: Although extensive experimental evidence on the process of liver regeneration exists, in humans, validation is largely missing. However, liver regeneration is critically affected by underlying liver disease. Within this project, we
Patrick Starlinger, Laura Brunnthaler, Chantal McCabe, David Pereyra, Jonas Santol, Jessica Steadman, Matthias Hackl, Susanna Skalicky, Hubert Hackl, Raphael Gronauer, Daniel O’Brien, Renate Kain, Petra Hirsova, Gregory J. Gores, Chen Wang, Thomas Gruenberger, Rory L. Smoot, Alice Assinger   +17 more
doaj   +1 more source

The role of gut microbiota in liver regeneration

Frontiers in Immunology, 2022
The liver has unique regeneration potential, which ensures the continuous dependence of the human body on hepatic functions. As the composition and function of gut microbiota has been gradually elucidated, the vital role of gut microbiota in liver ...
Zhe Xu, Zhe Xu, Nan Jiang, Nan Jiang, Yuanyuan Xiao, Yuanyuan Xiao, Kefei Yuan, Kefei Yuan, Zhen Wang, Zhen Wang   +9 more
doaj   +1 more source

15-Deoxy-Δ12,14-Prostaglandin J2 Inhibits Homing of Bone Marrow-Derived Mesenchymal Stem Cells Triggered by Chronic Liver Injury via Redox Pathway

PPAR Research, 2015
It has been reported that bone marrow-derived mesenchymal stem cells (BMSCs) have capacity to migrate to the damaged liver and contribute to fibrogenesis in chronic liver diseases.
Xin Liu, Shuangshuang Jia, Weiyang Li, Le Yang, Lin Yang, Lin Wang, Liying Li   +6 more
doaj   +1 more source

The Role of Immune Cells in Liver Regeneration

Livers, 2023
The liver is the only organ that can regenerate and regain its original tissue-to-body weight ratio within a short period of time after tissue loss.
Yankai Wen
doaj   +1 more source

Overexpression of apolipoprotein A-I alleviates endoplasmic reticulum stress in hepatocytes

Lipids in Health and Disease, 2017
Background Abnormal lipid metabolism may contribute to an increase in endoplasmic reticulum (ER) stress, resulting in the pathogenesis of non-alcoholic steatohepatitis.
Qing Guo, Can Zhang, Yutong Wang
doaj   +1 more source

Transplantation of Human Adipose Stem Cells Using Acellular Human Amniotic Membrane Improves Angiogenesis in Injured Endometrial Tissue in a Rat Intrauterine Adhesion Model

Cell Transplantation, 2020
Endometrial injury resulting in intrauterine adhesion is associated with extensive damage to the regenerative basal layer of the endometrium and represents a major therapeutic challenge.
Xiao Han, Yuejiao Ma, Xin Lu, Weihong Li, Enlan Xia, Tin-Chiu Li, Haiyan Zhang, Xiaowu Huang   +7 more
doaj   +1 more source

The Gut-Liver Axis in Health and Disease: The Role of Gut Microbiota-Derived Signals in Liver Injury and Regeneration

Frontiers in Immunology, 2021
Diverse liver diseases undergo a similar pathophysiological process in which liver regeneration follows a liver injury. Given the important role of the gut-liver axis in health and diseases, the role of gut microbiota-derived signals in liver injury and ...
Zhipeng Zheng, Baohong Wang
doaj   +1 more source

Risk factors for the development of cirrhosis within 1-year in non-cirrhotic patients with HBV- related acute-on-chronic liver failure

Frontiers in Medicine
Aims and BackgroundThis study aimed to provide a preliminary clarification of the predictive factors for the development of cirrhosis within 1-year cirrhosis in non-cirrhotic HBV-associated acute-on-chronic liver failure (HBV-ACLF) patients and develop a
Wenling Wang, Wenling Wang, Xiaolin Wang, Xiaolin Wang, Yu Wu, Yu Wu, Huaibin Zou, Huaibin Zou, Manman Xu, Manman Xu, Yu Chen, Yu Chen   +11 more
doaj   +1 more source

Regeneration and Recovery after Acetaminophen Hepatotoxicity

Livers, 2023
Liver regeneration is a compensatory response to tissue injury and loss. It is known that liver regeneration plays a crucial role in recovery following acetaminophen (APAP)-induced hepatotoxicity, which is the major cause of acute liver failure (ALF) in ...
Bharat Bhushan, Udayan Apte
doaj   +1 more source

ALR and Liver Regeneration

Molecular and Cellular Biochemistry, 2006
Liver possesses the capacity to restore its tissue mass and attain optimal volume in response to physical, infectious and toxic injury. The extraordinary ability of liver to regenerate is the effect of cross-talk between growth factors, cytokines, matrix components and many other factors.
Pawlowski, Rafał, Jura, Jolanta
openaire   +3 more sources