Results 11 to 20 of about 53,126,315 (234)
SP-LL-37, human antimicrobial peptide, enhances disease resistance in transgenic rice. [PDF]
PLoS ONE, 2017 Human LL-37 is a multifunctional antimicrobial peptide of cathelicidin family. It has been shown in recent studies that it can serve as a host's defense against influenza A virus.
In Hye Lee +6 more
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The Potential of Human Peptide LL-37 as an Antimicrobial and Anti-Biofilm Agent
Antibiotics, 2021 The rise in antimicrobial resistant bacteria threatens the current methods utilized to treat bacterial infections. The development of novel therapeutic agents is crucial in avoiding a post-antibiotic era and the associated deaths from antibiotic ...
Kylen E. Ridyard, Joerg Overhage
doaj +1 more source
Frontiers in Immunology, 2022 Human cathelicidin (LL-37) is a defense peptide with antimicrobial activity against various pathogens. However, LL-37 can also trigger tissue injury by binding to host cell membranes.
Lidia de Tapia +4 more
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Serum LL‐37 and inflammatory cytokines levels in psoriasis
Immunity, Inflammation and Disease, 2023 Background Psoriasis (PsO) is a T‐cell‐associated inflammatory autoimmune dermatitis. Leucine leucine‐37 (LL‐37) is upregulated in PsO patients and correlated with the area and severity of PsO.
Juanfeng Lao +5 more
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LL-37 induces polymerization and bundling of actin and affects actin structure. [PDF]
PLoS ONE, 2012 Actin exists as a monomer (G-actin) which can be polymerized to filaments) F-actin) that under the influence of actin-binding proteins and polycations bundle and contribute to the formation of the cytoskeleton.
Asaf Sol +3 more
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The ratio of serum LL-37 levels to blood leucocyte count correlates with COVID-19 severity
Scientific Reports, 2022 Beneficial effects of vitamin D on COVID-19 progression have been discussed in several studies. Vitamin D stimulates the expression of the antimicrobial peptide LL-37, and evidence shows that LL-37 can antagonize SARS-CoV-2.
Matthias Keutmann +7 more
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Bone Reports, 2020 Immunomodulatory peptide cathelicidin/LL-37 induces human monocyte differentiation into a novel bone repair cell, the monoosteophil. We now demonstrate that LL-37 is endocytosed by monocytes over a period of 6 days producing large (10 × 2 μm ...
Zhifang Zhang +5 more
doaj +1 more source
Frontiers in Pharmacology, 2022 Pancreatic cancer is amongst the most lethal malignancies, while its poor prognosis could be associated with promotion of autophagy and the tumor immune microenvironment.
Zhu Zhang +14 more
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Biochemistry and Biophysics Reports, 2022 The human antimicrobial peptide LL-37 permeabilizes the plasma membrane of host cells, but LL-37-induced direct effects on mitochondrial membrane permeability and function has not been reported.
Elisabeth Bankell +6 more
doaj +1 more source
Identifying the Critical Domain of LL-37 Involved in Mediating Neutrophil Activation in the Presence of Influenza Virus: Functional and Structural Analysis. [PDF]
PLoS ONE, 2015 The human cathelicidin LL-37 has been shown to play a role in host defense against influenza A viruses (IAV) through direct antiviral effects and through modulating inflammatory responses to infection.
Shweta Tripathi +5 more
doaj +1 more source