Results 21 to 30 of about 53,126,315 (234)
Significance of LL-37 on Immunomodulation and Disease Outcome [PDF]
, 2020 LL-37, also called cathelicidin, is an important part of the human immune system, which can resist various pathogens. A plethora of experiments have demonstrated that it has the multifunctional effects of immune regulation, in addition to antimicrobial ...
Yi, Zhengjun +11 more
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Frontiers in Bioscience-Landmark, 2021 Human cathelicidin antimicrobial peptide LL-37 (LL-37) is an antimicrobial peptide derived from its precursor protein hCAP18, which is an only cathelicidin in human.
Keqiang Chen +4 more
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Evaluation of the ability of LL-37 to neutralise LPS in vitro and ex vivo. [PDF]
PLoS ONE, 2011 BackgroundHuman cathelicidin LL-37 is a cationic antimicrobial peptide (AMP) which possesses a variety of activities including the ability to neutralise endotoxin. In this study, we investigated the role of LPS neutralisation in mediating LL-37's ability
Aaron Scott +9 more
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Characterizing the role of cell-wall β-1,3-exoglucanase Xog1p in Candida albicans adhesion by the human antimicrobial peptide LL-37. [PDF]
PLoS ONE, 2011 Candida albicans is the major fungal pathogen of humans. Its adhesion to host-cell surfaces is the first critical step during mucosal infection. Antimicrobial peptides play important roles in the first line of mucosal immunity against C.
Pei-Wen Tsai +3 more
doaj +1 more source
Cell Death Discovery, 2022 Cathelicidin hCAP18/LL-37 can resist infection from various pathogens and is an essential component of the human immune system. Accumulating evidence has indicated that hCAP18/LL-37 plays a tissue-specific role in human cancer.
Huidan Zhang +7 more
doaj +1 more source
Sequence and the expression construct of SP-LL-37.
, 2017 (A) Nucleotide sequence of SP-LL-37 containing the coding region and stop codon as well as the signal peptide (underlined). (B) Schematic diagram of the expression construct pSP1::SP-LL-37. Detection of Nos gene copy numbers in the T0 generation of pPZP::
Md. Amdadul Huq (3829780) +6 more
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LL-37 signaling increases CovS phosphatase activity.
, 2018 (A) Representative Western blot (top) and bar representation (bottom) depicting CovR~P levels and (B) hasA transcript levels (means ± standard deviations, n = 4) of indicated GAS strains grown to mid-exponential phase in THY or THY supplemented with ...
Nicola Horstmann (201711) +8 more
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PharmaceuticsBackground/Objectives: Glioblastomas (GBMs) are the most malignant and intractable of all cancers, with an unfavorable clinical prognosis for affected patients. The objective was to analyze the sensitivity of GBM cells to the antimicrobial peptides (AMPs)
Alexander N. Chernov +9 more
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Pharmaceuticals, 2016 Influenza A virus (IAV) remains a major threat that can cause severe morbidity and mortality due to rapid genomic variation. Resistance of IAVs to current anti-IAV drugs has been emerging, and antimicrobial peptides (AMPs) have been considered to be ...
I-Ni Hsieh, Kevan L. Hartshorn
doaj +1 more source
Identification of pPZP::SP-LL-37 insertion transgenic plants.
, 2017 The genomic structures of insertion alleles were determined by FST analysis in which boxes, bold lines, and triangles indicate exons, intron, and pPZP::SP-LL-37, respectively.
Md. Amdadul Huq (3829780) +6 more
core +1 more source