Results 31 to 40 of about 4,716 (190)
Neurochemical characterization of pERK-expressing spinal neurons in histamine-induced itch [PDF]
, 2015 Date of Acceptance: 08/07/2015 Acknowledgements This work was supported by grants from the Ministry of Science and Technology of China (2012CB966904, 2011CB51005), National Natural Science Foundation of China (31271182, 81200692, 91232724, 81200933 ...
Chai, Guo-Dong +11 more
core +1 more source
Molecular Ontology of the Nucleus of Solitary Tract. [PDF]
J Comp NeurolUsing histologic and transcriptomic analysis, we found that co‐expression of the transcription factors Lmx1b and Phox2b identifies glutamatergic neurons in the nucleus of the solitary tract (NTS), except for a caudal‐ventral band of neurons that include Gcg‐expressing neurons, which produce glucagon‐like peptide 1 (GLP‐1).
Gasparini S +4 more
europepmc +2 more sources
Neurogenin3 restricts serotonergic neuron differentiation to the hindbrain [PDF]
, 2014 The development of the nervous system is critically dependent on the production of functionally diverse neuronal cell types at their correct locations.
Carcagno, Abel Luis +4 more
core +1 more source
LMX1B-associated nephropathy that showed myelin figures on electron microscopy [PDF]
CEN Case Reports, 2021 The mutation of LIM homeodomain transcription factor LMX1B gene leads to nail-patella syndrome (NPS), which is characterized by dysplastic nails, hypoplastic patellae, iliac horns and nephropathy. The characteristic renal histological finding of NPS nephropathy is irregular thickening of the glomerular basement membrane with patchy lucent areas ...
Homare Shimohata +8 more
openaire +2 more sources
Frontiers in Pediatrics, 2021 Nail-patella syndrome (NPS) is a rare autosomal-dominant disorder characterized by the classic tetrad of absent or hypoplastic finger and toe nails, absent or hypoplastic patella, skeletal deformities involving the elbow joints, and iliac horns.
Ling Hou +4 more
doaj +1 more source
The FASEB Journal, 2006 The tetrapod limb develops asymmetrically along several axes. Lmx1b is responsible for dorsalization of the distal limb; knockout (KO) mice show ventral‐ventral limb patterning and reduction of the scapula, a dorsal structure of the limb girdle. However, the mechanism and downstream targets of Lmx1b are still unknown.
Charmaine Pira +2 more
openaire +1 more source
A Case Report of Nail-Patella Syndrome
罕见病研究, 2023 Nail-patella syndrome (NPS) is a hereditary rare disease that can involve fingernail, patella, elbow, and iliac bones. In this article, we report a case of a girl-9 and 1 quarter years old who had asthmatic contractures in both elbows, thumbnail ...
CHEN Dan +3 more
doaj +1 more source
Detection of genes regulated by Lmx1b during limb dorsalization [PDF]
Development, Growth & Differentiation, 2012 Lmx1b is a homeodomain transcription factor that regulates dorsal identity during limb development. Lmx1b knockout (KO) mice develop distal ventral–ventral limbs. Although induction of Lmx1b is linked to Wnt7a expression in the dorsal limb ectoderm, the downstream targets of Lmx1b that accomplish limb dorsalization are unknown.
Jennifer M, Feenstra +5 more
openaire +3 more sources
Postnatal maintenance of the 5-Ht1a-Pet1 autoregulatory loop by serotonin in the raphe nuclei of the brainstem [PDF]
, 2014 BACKGROUND: Despite the importance of 5-HT1A as a major target for the action of several anxiolytics/antidepressant drugs, little is known about its regulation in central serotonin (5-hydroxytryptamine, 5-HT) neurons.
Chen, Zhou-Feng +4 more
core +2 more sources
Frontiers in Genetics, 2021 Objective: Recent studies have demonstrated an association of single nucleotide polymorphisms (SNPs) rs35934224 in TXNRD2 and rs6478746 near LMX1B genes in primary open-angle glaucoma (POAG) among Europeans.
Altaf A. Kondkar +11 more
doaj +1 more source