Results 161 to 170 of about 117,740 (287)
Synthesis and Excellent Duplex Stability of Oligonucleotides Containing 2′-Amino-LNA Functionalized with Galactose Units [PDF]
Rajesh Kumar, Annika Ries, Jesper Wengel
openalex +1 more source
ABSTRACT Aim The glomerulus is a specialized microvascular unit that filters plasma through the coordinated function of podocytes and parietal epithelial cells (PECs). From this perspective, the glomerulus functions like a living hydrogeological filtration system.
Maria Elena Melica +3 more
wiley +1 more source
Implementing Genomic Medicine in Primary Care: A Convergent Mixed Method Case Study
ABSTRACT Purpose Despite the growing interest in implementing genomic medicine into primary care, numerous barriers persist. Herein we present formative work conducted at three primary care clinics to identify barriers to implementation as part of a state‐funded genomic medicine initiative.
Emory W. Heffernan +10 more
wiley +1 more source
ABSTRACT RNA interference (RNAi) is a highly conserved gene silencing mechanism regulating gene expression at transcriptional and post‐transcriptional levels in plants. Synthetic trans‐acting small interfering RNAs (syn‐tasiRNAs) have emerged as powerful tools for highly specific and efficient gene silencing.
Ariel H. Tomassi +8 more
wiley +1 more source
LNA modification of single-stranded DNA oligonucleotides allows subtle gene modification in mismatch-repair-proficient cells [PDF]
Thomas W van Ravesteyn +6 more
openalex +1 more source
Downregulation of microRNA‐494 drives mitochondrial biogenesis and function in trained muscle
Abstract MicroRNAs (miRNAs) are key regulators of cellular processes, including mitochondrial function and energy metabolism. This study explores the regulation of miR‐494 in skeletal muscle and circulation, investigating its response to exercise training and an acute exercise bout, its association with metabolic disorders, and the effects of ...
Natália Pálešová +10 more
wiley +1 more source
Locked nucleic acid (LNA) based PCR approach for the diagnosis and screening of spinal muscular atrophy [PDF]
Gökçe Güllü Amuran +4 more
openalex +1 more source
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Jiye Liu +3 more
openalex +2 more sources
Data-driven design of LNA-blockers for efficient contaminant removal in Ribo-Seq libraries. [PDF]
Ricciardi DA, Peter FE, Böhmer M.
europepmc +1 more source

