Results 171 to 180 of about 112,460 (239)

Investigation of lncRNA expression in newly diagnosed multiple myeloma reveals a LINC01432-CELF2 axis as an inhibitor of apoptosis. [PDF]

Oncogenesis
Mishra R, Thunuguntla P, Duraiyan D, Perkin A, Bagwill K, Gonzales S, Sizemore C, Brizuela V, King J, Daly S, Chang YJ, Abebe M, Rajana Y, Wichmann K, Enyan C, Rangineni S, Fiala M, Fortier J, Jayasinghe R, Schroeder M, Ding L, Vij R, DiPersio J, Silva-Fisher J.   +23 more
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Structural Characterization of <i>DDX23</i> 5' UTR Regulatory Elements and Their Targeting by LNA-Modified Antisense Oligonucleotides. [PDF]

Int J Mol Sci
Kamzeeva P, Shepelev N, Zabbarova V, Brylev V, Chistov A, Ryazantsev D, Kot E, Novopashina D, Rubtsova M, Aralov A.   +9 more
europepmc   +1 more source

Identification and functional validation of intracellular protein partners of phosphorothioate splice-switching oligonucleotides using AP-MS. [PDF]

Mol Ther Nucleic Acids
Gaci A, Menchon G, Bruce J, Salnot V, Pedeux R, Goyenvalle A.   +5 more
europepmc   +1 more source

Heterotrophic Prokaryote Host-Virus Dynamics During Spring in the Northeast Atlantic Ocean. [PDF]

Microorganisms
Das Y, Brussaard CPD, Mojica KDA.
europepmc   +1 more source

G4 Oligonucleotide-Based Chaperones of Heterogeneous Nuclear Ribonucleoprotein A1. [PDF]

Int J Mol Sci
Malakhova E, Svetlova J, Pavlova I, Alieva S, Severov V, Barinov N, Klinov D, Vedekhina T, Varizhuk A.   +8 more
europepmc   +1 more source

<i>DUX4</i> reduction and muscle function improvement by subcutaneous delivery of gapmer antisense oligonucleotides. [PDF]

Mol Ther Nucleic Acids
Zhang A, Lim KRQ, Chen Z, Yokota T, Chen YW.   +4 more
europepmc   +1 more source

Ligase-Catalyzed Transcription and Reverse Transcription of XNA by T3 DNA Ligase. [PDF]

Curr Protoc
Khamissi N, Rustico L, Hili R.
europepmc   +1 more source

miRNA-210 expression is associated with iron deficiency and biochemical parameters in hemodialysis patients. [PDF]

Front Med (Lausanne)
Kılıç M, Dheir H, İslam M, Ercan Z, Serdar MA.   +4 more
europepmc   +1 more source

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LNA and α-L-LNA: Towards Therapeutic Applications

Nucleosides, Nucleotides and Nucleic Acids, 2003
LNA and alpha-L-LNA are promising candidates for the development of efficient oligonucleotide-based therapeutic agents. Here, we report dose-dependent inhibition of HIV-1 Tat-dependent trans activation by a 12-mer chimeric alpha-L-LNA/DNA oligomer. This oligomer exhibits a dose-dependency similar to that of the corresponding 12-mer chimeric LNA/2'-O-Me-
Wengel, J., Vester, B., Lundberg, L.B., Douthwaite, S., Sørensen, M.D., Babu, B.R., Gait, M.J., Arzumanov, A., Petersen, M., Nielsen, J.T.   +9 more
openaire   +4 more sources