125 - 211 GHz low noise MMIC amplifier design for radio astronomy [PDF]
, 2019 To achieve the low noise and wide bandwidth required for millimeter wavelength astronomy applications, superconductor-insulator-superconductor (SIS) mixer based receiver systems have typically been used.
Cleary, Kieran +7 more
core +2 more sources
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
The intratracheal administration of locked nucleic acid containing antisense oligonucleotides induced gene silencing and an immune-stimulatory effect in the murine lung. [PDF]
PLoS ONE, 2017 Locked nucleic acid containing antisense oligonucleotides (LNA-ASOs) have the potential to modulate the disease-related gene expression by the RNaseH-dependent degradation of mRNAs.
Yasunori Uemura +2 more
doaj +1 more source
Assessment of MISR and MODIS cloud top heights through inter-comparison with a back-scattering lidar at SIRTA [PDF]
, 2004 One year of back-scattering lidar cloud boundaries and optical depth were analysed for coincident inter-comparison with the latest processed versions of the NASA-TERRA MISR stereo and MODIS CO2-slicing operational cloud top heights. Optically thin clouds
Delaval, A. +4 more
core +1 more source
Real‐Time 3D Ultrasound Imaging with an Ultra‐Sparse, Low Power Architecture
Advanced Healthcare Materials, EarlyView.This article presents a novel, ultra‐sparse ultrasound architecture that paves the way for wearable real‐time 3D imaging. By integrating a unique convolutional array with chirped data acquisition, the system achieves high‐resolution volumetric scans at a fraction of the power and hardware complexity.
Colin Marcus +9 more
wiley +1 more source
Locked nucleic acid oligomers as handles for single molecule manipulation. [PDF]
, 2014 Single-molecule manipulation (SMM) techniques use applied force, and measured elastic response, to reveal microscopic physical parameters of individual biomolecules and details of biomolecular interactions.
Berezney, John P, Saleh, Omar A
core +1 more source
Advances in MoS2‐Au Nanostructured Platforms for Cancer‐Derived miRNA Detection
Advanced Materials Interfaces, EarlyView.This figure presents the roadmap and scope of this review on microRNA detection technologies, with emphasis on MoS2 and MoS2–Au hybrid nanostructures. It traces the evolution from conventional assays to MoS2‐based SERS platforms, highlights synthesis, interfacial chemistry, and signal‐enhancement mechanisms, and summarizes key challenges and future ...
Faith Mokobi Zablon +2 more
wiley +1 more source
Molecular Therapy: Nucleic Acids, 2018 The successful development of high-affinity gapmer antisense oligonucleotide (ASO) therapeutics containing locked nucleic acid (LNA) or constrained ethyl (cEt) substitutions has been hampered by the risk of hepatotoxicity.
Andreas Dieckmann +7 more
doaj +1 more source
Utility of Lymph Node Aspiration in the Diagnosis of Visceral Leishmaniasis in Sudan. [PDF]
, 2007 We evaluated lymph node aspiration (LNA) as a simple diagnostic procedure for visceral leishmaniasis (VL). Lymph node aspiration was compared with the direct agglutination test (DAT) using a diagnostic titer > or = 1:6,400 in 7,880 suspected VL patients ...
Babiker, Z O E +4 more
core +1 more source
On the Angular Dependence of InP High Electron Mobility Transistors for Cryogenic Low Noise Amplifiers in a Magnetic Field [PDF]
, 2019 The InGaAs-InAlAs-InP high electron mobility transistor (InP HEMT) is the preferred active device used in a cryogenic low noise amplifier (LNA) for sensitive detection of microwave signals.
Bauch, Thilo +6 more
core +2 more sources