Results 1 to 10 of about 103,381 (175)

LncRNA HOXD-AS1 Is Upregulated in Ovarian Cancer [PDF]

open access: yesJournal of Cell and Molecular Research, 2021
Patients with ovarian cancer are mostly diagnosed at advanced stages which leads to poor prognosis and high mortality rate. Deregulation of lncRNA HOXD-AS1 expression associates with cancer development and metastasis.
Seyedeh Nahid Fotuhi   +2 more
doaj   +1 more source

Profiling of skeletal muscle tissue for long non-coding RNAs related to muscle metabolism in the QingYu pig at the growth inflection point [PDF]

open access: yesAnimal Bioscience, 2021
Objective Investigation of muscle growth at different developmental stages is an appropriate strategy for studying the mechanisms underlying muscle development and differences in phenotypes.
Jia Luo   +13 more
doaj   +1 more source

Identification and validation of tumor microenvironment-related lncRNA prognostic signature for uveal melanoma [PDF]

open access: yesInternational Journal of Ophthalmology, 2021
AIM: To investigate the role of tumor microenvironment (TME)-related long non-coding RNA (lncRNA) in uveal melanoma (UM), probable prognostic signature and potential small molecule drugs using bioinformatics analysis.
Chen-Lu Liao   +6 more
doaj   +1 more source

LncRNA NEAT1 modulates sorafenib resistance in hepatocellular carcinoma through regulating the miR-149-5p/AKT1 axis

open access: yesThe Saudi Journal of Gastroenterology, 2020
Background/Aims: The purpose of this study is to explore the expression characteristics of lncRNA NEAT1 in hepatocellular carcinoma (HCC) and the molecular mechanism of its regulation on sorafenib resistance.
Yuexiang Niu   +3 more
doaj   +1 more source

Emerging Concepts and Challenges in Rheumatoid Arthritis Gene Therapy

open access: yesBiomedicines, 2020
Rheumatoid arthritis (RA) is a systemic inflammatory joint disease affecting about 1% of the population worldwide. Current treatment approaches do not ensure a cure for every patient.
Andrei A. Deviatkin   +6 more
doaj   +1 more source

Role of long non-coding RNA OSER1-AS1 in non-small cell lung cancer lines

open access: yesDi-san junyi daxue xuebao, 2020
Objective To investigate the expression profile of long non-coding RNA (lncRNA) OSER1-AS1 in non-small-cell lung cancer (NSCLC) cell lines and its effect on the biological behaviors in these cells. Methods The expression level of OSER1-AS1 in 25 pairs of
WANG Youhao   +4 more
doaj   +1 more source

Role of LncRNAs in the Pathogenesis of Coronary Artery Disease

open access: yesReviews in Cardiovascular Medicine, 2023
Coronary artery disease (CAD), caused by coronary artery occlusion, is a common cardiovascular disease worldwide. Long non-coding RNAs (lncRNAs) are implicated in the regulation of endothelial cell injury, angiogenesis, plaque formation, and other ...
Xinyu Wu   +6 more
doaj   +1 more source

Identifying long non-coding RNAs and characterizing their functional roles in swine mammary gland from colostrogenesis to lactogenesis [PDF]

open access: yesAnimal Bioscience, 2022
Objective This study was conducted to identify the functional long non-coding RNAs (lncRNAs) for swine lactation by RNA-seq data of mammary gland. Methods According to the RNA-seq data of swine mammary gland, we screened lncRNAs, performed differential ...
Lijun Shi   +9 more
doaj   +1 more source

Serum Long-Noncoding RNA H19 and β-Catenin as Biomarkers for Early Diagnosis of Colorectal Cancer in Egyptian Patients: A Case Control Study

open access: yesJournal of Coloproctology, 2022
Colorectal cancer (CRC) is the third most prevalent cancer and the second most common cause of cancer death; however, its early detection can improve the survival. Colonic polyps are considered one of the CRC's major risk factors.
Ayat Abdelrahman Abdelrahman Elshazly   +4 more
doaj   +1 more source

Investigating the structure and function of Long Non-Coding RNA (LncRNA) and its role in cancer [PDF]

open access: yesCellular, Molecular and Biomedical Reports, 2022
Cancer is one of the most complex and common diseases affected by many factors. In recent years, many studies have been conducted on the genetic characteristics of cancer, among which we can mention lncRNA Long Non-Coding RNAs, which effectively ...
Hasan Alsaedy   +2 more
doaj   +1 more source

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