Results 1 to 10 of about 161,075 (345)

LncRNA GATA3-AS1 promotes the proliferation and migration of breast cancer cells and the mechanisms underlying its action [PDF]

Yixue xinzhi zazhi, 2022
Objective Long non-coding RNA (LncRNA) is closely related to the occurrence and development of various tumors. This study aimed to investigate the biological role and mechanism of LncRNA GATA3-AS1 in breast cancer progression.Methods The expression level
Qi JIANG, Yi-Qing XI, Lei WEI
doaj   +1 more source

LNCcation: lncRNA localization and function

Journal of Cell Biology, 2021
Bridges et al. discuss current knowledge, lingering questions, and emerging themes surrounding lncRNA subcellular localization and its impact on cellular functions.
M. C. Bridges, Amanda C. Daulagala, A. Kourtidis   +2 more
semanticscholar   +1 more source

Machine learning-based integration develops an immune-derived lncRNA signature for improving outcomes in colorectal cancer

Nature Communications, 2022
Long noncoding RNAs (lncRNAs) are recently implicated in modifying immunology in colorectal cancer (CRC). Nevertheless, the clinical significance of immune-related lncRNAs remains largely unexplored.
Zaoqu Liu, Long Liu, Siyuan Weng, C-C Guo, Q. Dang, Hui-Xian Xu, Libo Wang, Taoyuan Lu, Yuyuan Zhang, Zhenqiang Sun, Xinwei Han   +10 more
semanticscholar   +1 more source

Long Non-coding RNA INE1 Induced Autophagy Promotes Sensitivity of Prostate Cancer Cells to Cisplatin

Annals of Urologic Oncology, 2022
Prostate cancer is most prevalent malignancy of males in the world. In recent years, long non-coding RNAs (lncRNAs) were identified, and their functions are associated with prostate cancer initiation and progression.
Hezhen Chu, Kongdong Li, Jie Gu, Wenchao Xie, Yimin Xie, Jun Ma   +5 more
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Efficient and specific DNA oligonucleotide rRNA probe-based rRNA removal in Talaromyces marneffei

Mycology, 2022
Emerging evidence showed that lncRNAs play important roles in a wide range of biological processes of fungi such as Saccharomyces cerevisiae. However, systemic identification of lncRNAs in non-model fungi is a challenging task as the efficiency of rRNA ...
Xueyan Hu, Yun Zhang, Minghao Du, Ence Yang   +3 more
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LncRNA-mediated DNA methylation: an emerging mechanism in cancer and beyond

Journal of experimental & clinical cancer research : CR, 2022
DNA methylation is one of the most important epigenetic mechanisms to regulate gene expression, which is highly dynamic during development and specifically maintained in somatic cells.
Wanxu Huang, Hua Li, Qingsong Yu, Wei Xiao, D. Wang   +4 more
semanticscholar   +1 more source

A novel Cuproptosis-related LncRNA signature to predict prognosis in hepatocellular carcinoma

Scientific Reports, 2022
Increased intracellular toxicity due to an imbalance in copper homeostasis caused by copper ion accumulation could regulate the rate of cancer cell growth and proliferation.
Genhao Zhang, Jianping Sun, Xianwei Zhang   +2 more
semanticscholar   +1 more source

LncRNA-PACERR induces pro-tumour macrophages via interacting with miR-671-3p and m6A-reader IGF2BP2 in pancreatic ductal adenocarcinoma

Journal of Hematology & Oncology, 2022
Background LncRNA-PACERR plays critical role in the polarization of tissue-associated macrophages (TAMs). In this study, we found the function and molecular mechanism of PACERR in TAMs to regulate pancreatic ductal adenocarcinoma (PDAC) progression ...
Yihao Liu, Minmin Shi, Xingfeng He, Yi-lin Cao, P. Liu, Fanlu Li, Siyi Zou, Chenlei Wen, Q. Zhan, Zhiwei Xu, Jiancheng Wang, Baofa Sun, Baiyong Shen   +12 more
semanticscholar   +1 more source

Emerging role of tumor-related functional peptides encoded by lncRNA and circRNA

Molecular Cancer, 2020
Non-coding RNAs do not encode proteins and regulate various oncological processes. They are also important potential cancer diagnostic and prognostic biomarkers.
Pan Wu, Yongzhen Mo, M. Peng, T. Tang, Y. Zhong, Xiangying Deng, F. Xiong, Can Guo, Xu Wu, Yong Li, Xiaoling Li, Gui-yuan Li, Zhaoyang Zeng, W. Xiong   +13 more
semanticscholar   +1 more source

LncRNA HEPFAL accelerates ferroptosis in hepatocellular carcinoma by regulating SLC7A11 ubiquitination

Cell Death and Disease, 2022
Ferroptosis is a new type of cell death that has been recognized in recent years and is different from apoptosis, autophagy, and necrosis. It is mainly due to cellular iron homeostasis and lipid peroxidation of iron metabolism caused by large ...
Baofu Zhang, Wenming Bao, Sina Zhang, Bo Chen, Xiang Zhou, Jungang Zhao, Zhehao Shi, Tan Zhang, Ziyan Chen, Luhui Wang, Xiangtao Zheng, Gang Chen, Yi Wang   +12 more
semanticscholar   +1 more source