Results 1 to 10 of about 63,220 (230)

LncRNA–protein interaction prediction with reweighted feature selection [PDF]

BMC Bioinformatics, 2023
LncRNA–protein interactions are ubiquitous in organisms and play a crucial role in a variety of biological processes and complex diseases. Many computational methods have been reported for lncRNA–protein interaction prediction.
Guohao Lv, Yingchun Xia, Zhao Qi, Zihao Zhao, Lianggui Tang, Cheng Chen, Shuai Yang, Qingyong Wang, Lichuan Gu   +8 more
doaj   +2 more sources

Predicting lncRNA–Protein Interaction With Weighted Graph-Regularized Matrix Factorization [PDF]

Frontiers in Genetics, 2021
Long non-coding RNAs (lncRNAs) are widely concerned because of their close associations with many key biological activities. Though precise functions of most lncRNAs are unknown, research works show that lncRNAs usually exert biological function by ...
Xibo Sun, Leiming Cheng, Jinyang Liu, Jinyang Liu, Cuinan Xie, Cuinan Xie, Jiasheng Yang, Fu Li   +7 more
doaj   +2 more sources

LPI-EnEDT: an ensemble framework with extra tree and decision tree classifiers for imbalanced lncRNA-protein interaction data classification [PDF]

BioData Mining, 2021
Background Long noncoding RNAs (lncRNAs) have dense linkages with various biological processes. Identifying interacting lncRNA-protein pairs contributes to understand the functions and mechanisms of lncRNAs. Wet experiments are costly and time-consuming.
Lihong Peng, Ruya Yuan, Ling Shen, Pengfei Gao, Liqian Zhou   +4 more
doaj   +2 more sources

Projection-Based Neighborhood Non-Negative Matrix Factorization for lncRNA-Protein Interaction Prediction [PDF]

Frontiers in Genetics, 2019
Many long ncRNAs (lncRNA) make their effort by interacting with the corresponding RNA-binding proteins, and identifying the interactions between lncRNAs and proteins is important to understand the functions of lncRNA. Compared with the time-consuming and
Yingjun Ma, Yingjun Ma, Tingting He, Tingting He, Xingpeng Jiang, Xingpeng Jiang   +5 more
doaj   +2 more sources

A Hybrid Prediction Method for Plant lncRNA-Protein Interaction [PDF]

Cells, 2019
Long non-protein-coding RNAs (lncRNAs) identification and analysis are pervasive in transcriptome studies due to their roles in biological processes. In particular, lncRNA-protein interaction has plausible relevance to gene expression regulation and in ...
Jael Sanyanda Wekesa, Yushi Luan, Ming Chen, Jun Meng   +3 more
doaj   +2 more sources

Protocol for detecting lncRNA-protein interaction in vivo using the yeast three-hybrid assay [PDF]

STAR Protocols
Summary: Analyses of long non-coding RNA (lncRNA)-protein interactions provide key clues for understanding the molecular basis of lncRNA-modulated biological processes. Here, we detail a yeast three-hybrid assay to identify the lncRNA-interacting protein.
Jingjing Cai, Reqing He, Yongdi Zhang, Pengxiang Zhang, Youlin Zhu, Dong Wang   +5 more
doaj   +2 more sources

LPInsider: a webserver for lncRNA–protein interaction extraction from the literature [PDF]

BMC Bioinformatics, 2022
Background Long non-coding RNA (LncRNA) plays important roles in physiological and pathological processes. Identifying LncRNA–protein interactions (LPIs) is essential to understand the molecular mechanism and infer the functions of lncRNAs.
Ying Li, Lizheng Wei, Cankun Wang, Jianing Zhao, Siyu Han, Yu Zhang, Wei Du   +6 more
doaj   +2 more sources

LncRNA ENST00000532153.1 alleviates podocyte injury by inhibiting PARP1-mediated PARylation of ATF3 in diabetic kidney disease [PDF]

Cellular and Molecular Life Sciences
Podocyte injury is a key event in the progression of diabetic kidney disease (DKD), and the role of long noncoding RNAs (lncRNAs) in DKD and podocyte injury is emerging.
Qun Yu, Meilin Yang, Shangwei Lu, Hong Su, Yue Liu, Xia Zhang, Xiaoting Fan, Zhimei Lv, Rong Wang   +8 more
doaj   +2 more sources

Long non-coding RNA HCP5 accelerated malignant progression of ovarian cancer by inhibiting ferroptosis through interaction with polypyrimidine tract binding protein 1 [PDF]

Journal of Ovarian Research
Background Ovarian cancer (OVCA) is the third most common gynaecological malignancy worldwide. Long non-coding RNA (LncRNA) HCP5 and polypyrimidine tract binding protein 1 (PTBP1) involved in regulating tumors, however, with undefined mechanism in OVCA ...
Xiaoli Chen, Qing Ren, Xiaoyu Zheng, Qifeng Shen, Jian Shou   +4 more
doaj   +2 more sources

Prediction of lncRNA–Protein Interactions via the Multiple Information Integration

Frontiers in Bioengineering and Biotechnology, 2021
The long non-coding RNA (lncRNA)–protein interaction plays an important role in the post-transcriptional gene regulation, such as RNA splicing, translation, signaling, and the development of complex diseases.
Yifan Chen, Yifan Chen, Xiangzheng Fu, Zejun Li, Li Peng, Linlin Zhuo   +5 more
doaj   +1 more source