Results 21 to 30 of about 48,734 (209)

LPIH2V: LncRNA-protein interactions prediction using HIN2Vec based on heterogeneous networks model

open access: yesFrontiers in Genetics, 2023
LncRNA-protein interaction plays an important role in the development and treatment of many human diseases. As the experimental approaches to determine lncRNA–protein interactions are expensive and time-consuming, considering that there are few ...
Meng-Meng Wei   +8 more
doaj   +1 more source

LncRNA expression profile in human malignant embryonic rhabdomyosarcoma cell line infected with Coxsackie virus group B type 5 [PDF]

open access: yesJichu yixue yu linchuang, 2022
Objective To explore the molecular mechanism of the interaction between Coxsackie virus group B type 5 (CVB5) and the host, The long non-coding RNA(lncRNA) expression profile in human malignant embryonic rhabdomyosarcoma cell line (RD) infected by CVB5 ...
TENG Pei-ying, LI Jing, SHI Yu-lu, YANG Fan, OU Xia, CHEN Wei
doaj   +1 more source

SGII: Systematic Identification of Essential lncRNAs in Mouse and Human Genome With lncRNA-Protein-Protein Heterogeneous Interaction Network

open access: yesFrontiers in Genetics, 2022
Long noncoding RNAs (lncRNAs) play important roles in a variety of biological processes. Knocking out or knocking down some lncRNA genes can lead to death or infertility. These lncRNAs are called essential lncRNAs.
Xiao-Hong Xin   +5 more
doaj   +1 more source

Predicting lncRNA-protein interactions with bipartite graph embedding and deep graph neural networks

open access: yesFrontiers in Genetics, 2023
Background: Long non-coding RNAs (lncRNAs) play crucial roles in numerous biological processes. Investigation of the lncRNA-protein interaction contributes to discovering the undetected molecular functions of lncRNAs.
Yuzhou Ma   +3 more
doaj   +1 more source

Long noncoding RNA HOTAIR interacts with Y-Box Protein-1 (YBX1) to regulate cell proliferation

open access: yesLife Science Alliance, 2021
The authors determined that HOTAIR specifically bind to YBX1 and promote its nuclear translocation, and then regulating cell proliferation by stimulating the PI3K/Akt and ERK/RSK signaling pathways. HOTAIR is a long noncoding RNA (lncRNA) which serves as
Siting Li   +8 more
doaj   +1 more source

Predicting lncRNA–Protein Interactions With miRNAs as Mediators in a Heterogeneous Network Model

open access: yesFrontiers in Genetics, 2020
Long non-coding RNAs (lncRNAs) play important roles in various biological processes, where lncRNA–protein interactions are usually involved. Therefore, identifying lncRNA–protein interactions is of great significance to understand the molecular functions
Yuan-Ke Zhou   +5 more
doaj   +1 more source

PRPI-SC: an ensemble deep learning model for predicting plant lncRNA-protein interactions

open access: yesBMC Bioinformatics, 2021
Background Plant long non-coding RNAs (lncRNAs) play vital roles in many biological processes mainly through interactions with RNA-binding protein (RBP).
Haoran Zhou   +3 more
doaj   +1 more source

The Bipartite Network Projection-Recommended Algorithm for Predicting Long Non-coding RNA-Protein Interactions

open access: yesMolecular Therapy: Nucleic Acids, 2018
With the development of science and biotechnology, many evidences show that ncRNAs play an important role in the development of important biological processes, especially in chromatin modification, cell differentiation and proliferation, RNA progressing,
Qi Zhao   +5 more
doaj   +1 more source

Elucidating the Molecular Mechanism of Ischemic Stroke Using Integrated Analysis of miRNA, mRNA, and lncRNA Expression Profiles

open access: yesFrontiers in Integrative Neuroscience, 2021
Objective: This study aimed to investigate the possible molecular mechanisms associated with ischemic stroke through the construction of a lncRNA-miRNA-mRNA network.
Yaxuan Sun   +5 more
doaj   +1 more source

Comprehensive analysis of lncRNA-mediated ceRNA regulatory networks and key genes associated with papillary thyroid cancer coexistent with Hashimoto’s thyroiditis

open access: yesBMC Endocrine Disorders, 2022
Objective The incidence of papillary thyroid cancer (PTC) concomitant with Hashimoto’s thyroiditis (HT) is gradually increasing over the past decades.
Yuepeng Zhang, Yueli Tian
doaj   +1 more source

Home - About - Disclaimer - Privacy