Results 11 to 20 of about 752,944 (283)

Prediction of lncRNA–Protein Interactions via the Multiple Information Integration [PDF]

Frontiers in Bioengineering and Biotechnology, 2021
The long non-coding RNA (lncRNA)–protein interaction plays an important role in the post-transcriptional gene regulation, such as RNA splicing, translation, signaling, and the development of complex diseases.
Yifan Chen, Yifan Chen, Xiangzheng Fu, Zejun Li, Li Peng, Linlin Zhuo   +5 more
doaj   +4 more sources

LPIH2V: LncRNA-protein interactions prediction using HIN2Vec based on heterogeneous networks model

Frontiers in Genetics, 2023
LncRNA-protein interaction plays an important role in the development and treatment of many human diseases. As the experimental approaches to determine lncRNA–protein interactions are expensive and time-consuming, considering that there are few ...
Meng-Meng Wei, Chang-Qing Yu, Li-Ping Li, Li-Ping Li, Zhu-Hong You, Zhong-Hao Ren, Yong-Jian Guan, Xin-Fei Wang, Yue-Chao Li   +8 more
doaj   +4 more sources

LPI-NRLMF: lncRNA-protein interaction prediction by neighborhood regularized logistic matrix factorization. [PDF]

Oncotarget, 2017
LncRNA-protein interactions play important roles in many important cellular processes including signaling, transcriptional regulation, and even the generation and progression of complex diseases.
Liu H, Ren G, Hu H, Zhang L, Ai H, Zhang W, Zhao Q.   +6 more
europepmc   +5 more sources

Predicting lncRNA-protein interactions with bipartite graph embedding and deep graph neural networks

Frontiers in Genetics, 2023
Background: Long non-coding RNAs (lncRNAs) play crucial roles in numerous biological processes. Investigation of the lncRNA-protein interaction contributes to discovering the undetected molecular functions of lncRNAs.
Yuzhou Ma, Han Zhang, Chen Jin, Chuanze Kang   +3 more
doaj   +4 more sources

PRPI-SC: an ensemble deep learning model for predicting plant lncRNA-protein interactions [PDF]

BMC Bioinformatics, 2021
Background Plant long non-coding RNAs (lncRNAs) play vital roles in many biological processes mainly through interactions with RNA-binding protein (RBP).
Haoran Zhou, Jael Sanyanda Wekesa, Yushi Luan, Jun Meng   +3 more
doaj   +4 more sources

Prediction of lncRNA-protein interactions using HeteSim scores based on heterogeneous networks

Scientific Reports, 2017
Massive studies have indicated that long non-coding RNAs (lncRNAs) are critical for the regulation of cellular biological processes by binding with RNA-related proteins.
Yun Xiao, Jingpu Zhang, Lei Deng
doaj   +4 more sources

Protocol for detecting lncRNA-protein interaction in vivo using the yeast three-hybrid assay [PDF]

STAR Protocols
Summary: Analyses of long non-coding RNA (lncRNA)-protein interactions provide key clues for understanding the molecular basis of lncRNA-modulated biological processes. Here, we detail a yeast three-hybrid assay to identify the lncRNA-interacting protein.
Jingjing Cai, Reqing He, Yongdi Zhang, Pengxiang Zhang, Youlin Zhu, Dong Wang   +5 more
doaj   +4 more sources

Predicting lncRNA–Protein Interactions With miRNAs as Mediators in a Heterogeneous Network Model [PDF]

Frontiers in Genetics, 2020
Long non-coding RNAs (lncRNAs) play important roles in various biological processes, where lncRNA–protein interactions are usually involved. Therefore, identifying lncRNA–protein interactions is of great significance to understand the molecular functions
Yuan-Ke Zhou, Zi-Ang Shen, Han Yu, Tao Luo, Yang Gao, Pu-Feng Du   +5 more
doaj   +4 more sources

LPI-SKF: Predicting lncRNA-Protein Interactions Using Similarity Kernel Fusions [PDF]

Frontiers in Genetics, 2020
Long non-coding RNAs (lncRNAs) play an important role in serval biological activities, including transcription, splicing, translation, and some other cellular regulation processes.
Yuan-Ke Zhou, Jie Hu, Zi-Ang Shen, Wen-Ya Zhang, Pu-Feng Du   +4 more
doaj   +4 more sources

RLF-LPI: An ensemble learning framework using sequence information for predicting lncRNA-protein interaction based on AE-ResLSTM and fuzzy decision

Mathematical Biosciences and Engineering, 2022
Long non-coding RNAs (lncRNAs) play a regulatory role in many biological cells, and the recognition of lncRNA-protein interactions is helpful to reveal the functional mechanism of lncRNAs.
Jinmiao Song, Shengwei Tian, Long Yu, Qimeng Yang , Qiguo Dai , Yuanxu Wang, Weidong Wu, Xiaodong Duan   +7 more
doaj   +2 more sources