Results 21 to 30 of about 752,944 (283)

IRWNRLPI: Integrating Random Walk and Neighborhood Regularized Logistic Matrix Factorization for lncRNA-Protein Interaction Prediction. [PDF]

Front Genet, 2018
Long non-coding RNA (lncRNA) plays an important role in many important biological processes and has attracted widespread attention. Although the precise functions and mechanisms for most lncRNAs are still unknown, we are certain that lncRNAs usually ...
Zhao Q, Zhang Y, Hu H, Ren G, Zhang W, Liu H.   +5 more
europepmc   +2 more sources

SGII: Systematic Identification of Essential lncRNAs in Mouse and Human Genome With lncRNA-Protein-Protein Heterogeneous Interaction Network

Frontiers in Genetics, 2022
Long noncoding RNAs (lncRNAs) play important roles in a variety of biological processes. Knocking out or knocking down some lncRNA genes can lead to death or infertility. These lncRNAs are called essential lncRNAs.
Xiao-Hong Xin, Ying-Ying Zhang, Chu-Qiao Gao, Hui Min, Likun Wang, Pu-Feng Du   +5 more
doaj   +2 more sources

A Survey of Current Resources to Study lncRNA-Protein Interactions [PDF]

Non-Coding RNA, 2021
Phenotypes are driven by regulated gene expression, which in turn are mediated by complex interactions between diverse biological molecules. Protein–DNA interactions such as histone and transcription factor binding are well studied, along with RNA–RNA ...
Melcy Philip, Tyrone Chen, S. Tyagi
semanticscholar   +6 more sources

LPI-KTASLP: Prediction of LncRNA-Protein Interaction by Semi-Supervised Link Learning With Multivariate Information

IEEE Access, 2019
Long non-coding RNA, also known as lncRNA, is a series of single-stranded polynucleotides (no less than 200 nucleotides each), consisting of non-protein coding transcripts.
Cong Shen, Yijie Ding, Jijun Tang, Limin Jiang, Fei Guo   +4 more
doaj   +2 more sources

Revealing protein-lncRNA interaction [PDF]

Briefings Bioinform., 2015
Long non-coding RNAs (lncRNAs) are associated to a plethora of cellular functions, most of which require the interaction with one or more RNA-binding proteins (RBPs); similarly, RBPs are often able to bind a large number of different RNAs.
Colantoni, A, Ferrè, F, Helmer-Citterich, M   +2 more
core   +2 more sources

Deciphering LncRNA–protein interactions using docking complexes

Journal of Biomolecular Structure and Dynamics, 2020
Deciphering RNA–protein interactions are important to study principal biological mechanisms including transcription and translation regulation, gene silencing, among others.
Renuka Suravajhala, Sonal Gupta, Narayan Kumar, P. Suravajhala   +3 more
semanticscholar   +3 more sources

LncRNA ENST00000532153.1 alleviates podocyte injury by inhibiting PARP1-mediated PARylation of ATF3 in diabetic kidney disease [PDF]

Cellular and Molecular Life Sciences
Podocyte injury is a key event in the progression of diabetic kidney disease (DKD), and the role of long noncoding RNAs (lncRNAs) in DKD and podocyte injury is emerging.
Qun Yu, Meilin Yang, Shangwei Lu, Hong Su, Yue Liu, Xia Zhang, Xiaoting Fan, Zhimei Lv, Rong Wang   +8 more
doaj   +2 more sources

Long non-coding RNA HCP5 accelerated malignant progression of ovarian cancer by inhibiting ferroptosis through interaction with polypyrimidine tract binding protein 1 [PDF]

Journal of Ovarian Research
Background Ovarian cancer (OVCA) is the third most common gynaecological malignancy worldwide. Long non-coding RNA (LncRNA) HCP5 and polypyrimidine tract binding protein 1 (PTBP1) involved in regulating tumors, however, with undefined mechanism in OVCA ...
Xiaoli Chen, Qing Ren, Xiaoyu Zheng, Qifeng Shen, Jian Shou   +4 more
doaj   +2 more sources

Multi-feature fusion for deep learning to predict plant lncRNA-protein interaction.

Genomics, 2020
Long non-coding RNAs (lncRNAs) play key roles in regulating cellular biological processes through diverse molecular mechanisms including binding to RNA binding proteins. The majority of plant lncRNAs are functionally uncharacterized, thus, accurate prediction of plant lncRNA-protein interaction is imperative for subsequent functional studies.
J. Wekesa, Jun Meng, Yushi Luan
semanticscholar   +3 more sources

Predicting lncRNA–Protein Interactions by Heterogenous Network Embedding [PDF]

Frontiers in Genetics, 2022
lncRNA–protein interactions play essential roles in a variety of cellular processes. However, the experimental methods for systematically mapping of lncRNA–protein interactions remain time-consuming and expensive. Therefore, it is urgent to develop reliable computational methods for predicting lncRNA–protein interactions.
Guoqing Zhao, Pengpai Li, Xu Qiao, Xianhua Han, Zhi-Ping Liu   +4 more
openaire   +3 more sources