Results 31 to 40 of about 752,944 (283)

LncRNA expression profile in human malignant embryonic rhabdomyosarcoma cell line infected with Coxsackie virus group B type 5 [PDF]

Jichu yixue yu linchuang, 2022
Objective To explore the molecular mechanism of the interaction between Coxsackie virus group B type 5 (CVB5) and the host, The long non-coding RNA(lncRNA) expression profile in human malignant embryonic rhabdomyosarcoma cell line (RD) infected by CVB5 ...
TENG Pei-ying, LI Jing, SHI Yu-lu, YANG Fan, OU Xia, CHEN Wei
doaj   +1 more source

Function of lncRNAs and approaches to lncRNA-protein interactions [PDF]

Science China Life Sciences, 2013
Long non-coding RNAs (lncRNAs), which represent a new frontier in molecular biology, play important roles in regulating gene expression at epigenetic, transcriptional and post-transcriptional levels. More and more lncRNAs have been found to play important roles in normal cell physiological activities, and participate in the development of varieties of ...
Zhu, JuanJuan, Fu, HanJiang, Wu, YongGe, Zheng, XiaoFei   +3 more
openaire   +2 more sources

The Challenges and Opportunities of lncRNAs in Ovarian Cancer Research and Clinical Use [PDF]

, 2020
[Abstract] Ovarian cancer is one of the most lethal gynecological malignancies worldwide because it tends to be detected late, when the disease has already spread, and prognosis is poor.
Barreiro-Alonso, Aida, Cerdán, María Esperanza, Lamas, Mónica, Quindós-Varela, María, Rodríguez-Belmonte, Esther, Salamini-Montemurri, Martín, Vizoso-Vázquez, Ángel   +6 more
core   +1 more source

LPI-CSFFR: Combining Serial Fusion with Feature Reuse for Predicting LncRNA-Protein Interactions [PDF]

Computational Biology and Chemistry, 2022
<p>Long non-coding RNAs (LncRNAs) play important roles in a series of life activities, and they function primarily with proteins. The wet experimental-based methods in lncRNA-protein interactions (lncRPIs) study are time-consuming. Therefore, in this study, we propose a reliable computational-based method called LPI-CSFFR using sequences ...
Xiaoqian, Huang, Yi, Shi, Jing, Yan, Wenyan, Qu, Xiaoyi, Li, Jianjun, Tan   +5 more
openaire   +2 more sources

Probing lncRNA–Protein Interactions: Data Repositories, Models, and Algorithms

Frontiers in Genetics, 2020
Identifying lncRNA-protein interactions (LPIs) is vital to understanding various key biological processes. Wet experiments found a few LPIs, but experimental methods are costly and time-consuming. Therefore, computational methods are increasingly exploited to capture LPI candidates.
Lihong Peng, Fuxing Liu, Jialiang Yang, Xiaojun Liu, Yajie Meng, Xiaojun Deng, Cheng Peng, Geng Tian, Liqian Zhou   +8 more
openaire   +3 more sources

Integrative analyses of transcriptome sequencing identify novel functional lncRNAs in esophageal squamous cell carcinoma. [PDF]

, 2017
Long non-coding RNAs (lncRNAs) have a critical role in cancer initiation and progression, and thus may mediate oncogenic or tumor suppressing effects, as well as be a new class of cancer therapeutic targets. We performed high-throughput sequencing of RNA
Ai, B, Bai, X-F, Cao, H-H, Feng, C-C, He, J-Z, Huang, G-W, Koeffler, HP, Lei, F, Li, C-Q, Li, E-M, Li, M, Li, S, Li, X, Li, X-C, Liao, L-D, Lin, D-C, Liu, Y-J, Shen, J-H, Tang, Z-D, Wang, L-D, Wang, M-R, Wang, Q-Y, Wang, S-H, Wu, B-L, Wu, J-Y, Wu, Z-Y, Xu, L-Y, Xu, Y-J, Xue, Y-J, Zhang, J, Zhao, J-M, Zheng, C-P, Zhu, Y   +32 more
core   +1 more source

Elucidating the Molecular Mechanism of Ischemic Stroke Using Integrated Analysis of miRNA, mRNA, and lncRNA Expression Profiles

Frontiers in Integrative Neuroscience, 2021
Objective: This study aimed to investigate the possible molecular mechanisms associated with ischemic stroke through the construction of a lncRNA-miRNA-mRNA network.
Yaxuan Sun, Jing Wang, Bin Han, Kun Meng, Yan Han, Yongxia Ding   +5 more
doaj   +1 more source

The long non-coding RNA Kcnq1ot1 controls maternal p57 expression in muscle cells by promoting H3K27me3 accumulation to an intragenic MyoD-binding region [PDF]

, 2019
BACKGROUND: The cell-cycle inhibitor p57kip2 plays a critical role in mammalian development by coordinating cell proliferation and differentiation in many cell types.
Andresini, Oriella, Maione, Rossella, Matteini, Francesca, Petrai, Stefano, Rossi, Marianna Nicoletta, Santini, Tiziana   +5 more
core   +4 more sources

The Bipartite Network Projection-Recommended Algorithm for Predicting Long Non-coding RNA-Protein Interactions

Molecular Therapy: Nucleic Acids, 2018
With the development of science and biotechnology, many evidences show that ncRNAs play an important role in the development of important biological processes, especially in chromatin modification, cell differentiation and proliferation, RNA progressing,
Qi Zhao, Haifan Yu, Zhong Ming, Huan Hu, Guofei Ren, Hongsheng Liu   +5 more
doaj   +1 more source

The Landscape of Long Non-Coding RNA Dysregulation and Clinical Relevance in Muscle Invasive Bladder Urothelial Carcinoma. [PDF]

, 2019
Bladder cancer is one of the most common cancers in the United States, but few advancements in treatment options have occurred in the past few decades.
Chang, Eric Y, Chu, Megan, High, Rachel A, Li, Wei Tse, Ongkeko, Weg M, Shen, Haotian, Wang-Rodriguez, Jessica, Wong, Lindsay M   +7 more
core   +1 more source