Results 71 to 80 of about 33,666 (150)
Cell Biochemistry and Function, Volume 44, Issue 8, August 2026.ABSTRACT Osteoporosis arises from an imbalance among osteoblast‐mediated bone formation, osteoclast‐mediated bone resorption, and osteocyte‐directed mechanosensory control, but the molecular events that connect aging, hormonal change, inflammation, and mechanical unloading to bone loss remain incompletely resolved.
Minjuan Du, Leisheng Wang
wiley +1 more source
Aging Cell, Volume 25, Issue 8, August 2026.Schematic diagram illustrating the molecular mechanism by which lncRNA AK050834 drives vascular smooth muscle cell (VSMC) senescence. Extracellular stimuli, including D‐galactose and natural aging, induce the upregulation of AK050834. AK050834 exerts dual regulatory functions: (1) In the nucleus, it directly binds to the ATF3 promoter region to ...
Haoran Wu +9 more
wiley +1 more source
Expression Landscape and Circadian Regulation of lncRNAs in the Kidney
Acta Physiologica, Volume 242, Issue 8, August 2026.ABSTRACT Recent multi‐omics work shows that the diurnal rhythmicity of kidney function is associated with circadian oscillations in renal mRNA, protein and metabolite abundances. Yet circadian regulation of renal lncRNAs, which are emerging as important modulators of diverse (patho)physiological processes, remains largely unexplored. Here, we provide a
Leonore Wigger +4 more
wiley +1 more source
International Journal of Cancer, Volume 159, Issue 2, Page 302-319, 15 July 2026.Abstract Tumor‐educated platelets (TEPs) are emerging as a compelling frontier in liquid biopsy, functioning as dynamic, systemic sensors that sequester and process tumor‐derived biomolecules. This interaction imprints an integrated molecular signature of malignancy—spanning the transcriptome, proteome, lipidome, and crucially, the captured genome ...
Whi‐An Kwon +5 more
wiley +1 more source
Functional dissection of the Xist lncRNA conserved sequences in X-chromosome inactivation
, 2019 Tese de mestrado, Biologia Molecular e Genética, Universidade de Lisboa, Faculdade de Ciências, 2019Introduction: Due to the discrepancy in the number of X chromosomes between the sexes in many animal species, dosage compensation mechanisms have evolved ...
Gil, Cláudia Raquel Estopa
core +2 more sources
Annals of Hematologyβ-thalassemia is an inherited blood disorder with long-term associated complications. The purpose of this study was to evaluate the clinical significance of the lncRNA-HBBP1 and lncRNA-XIST expression profiles in the diagnosis of β-thalassemia patients ...
Abdallah M. Gameel +11 more
doaj +1 more source
Association Between Serum lncRNA XIST Levels and Depressive Disorder
Long non-coding RNA (lncRNA) XIST has been implicated in the pathogenesis of depression, yet its precise role in the disorder remains inadequately understood.
Peng, Rui
core +1 more source
, 2017 Tumor progression and metastasis is the main cause of death in colorectal cancer (CRC). Long noncoding RNAs (lncRNAs) are critical regulators in various diseases including human cancer.
Zhao-lei Zeng +10 more
core +1 more source
SHAPE reveals transcript-wide interactions, complex structural domains, and protein interactions across the Xist lncRNA in living cells [PDF]
, 2016 Long noncoding RNAs (lncRNAs) are important regulators of gene expression, but their structural features are largely unknown. We used structure-selective chemical probing to examine the structure of the Xist lncRNA in living cells and found that the RNA ...
Inoue, Kaoru +8 more
core +1 more source
Long Noncoding RNA XIST Regulates miR-137‐EZH2 Axis to Promote Tumor Metastasis in Colorectal Cancer
, 2018 We aimed to investigate the significant role of long noncoding RNA X inactive specific transcript (XIST) in regulating tumor metastasis in colorectal cancer (CRC), as well as its possible mechanism.
Xingxiang Liu, Dong Hua, Lin Cui
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