Results 81 to 90 of about 33,666 (150)

NYU-BFX/lncRNA-screen: v0.1

, 2016
lncRNA ...
gongyixiao, Aristotelis Tsirigos
core   +1 more source

Discovering therapeutic possibilities for polycystic ovary syndrome by targeting XIST and its associated ceRNA network through the analysis of transcriptome data

Scientific Reports
Long non-coding RNA (lncRNA) regulates many physiological processes by acting as competitive endogenous RNA (ceRNA). The dysregulation of lncRNA X-inactive specific transcript (XIST) has been shown in various human disorders.
Elahe Berenji, Ali Valipour Motlagh, Marziyeh Fathi, Maryam Esmaeili, Tayebeh Izadi, Parsa Rezvanian, Maryam Zanjirband, Zahra Safaeinejad, Mohammad Hossein Nasr-Esfahani   +8 more
doaj   +1 more source

XIST and MUC1-C form an auto-regulatory pathway in driving cancer progression

Cell Death and Disease
The long non-coding RNA X-inactive specific transcript (lncRNA XIST) and MUC1 gene are dysregulated in chronic inflammation and cancer; however, there is no known interaction of their functions.
Keyi Wang, Atrayee Bhattacharya, Naoki Haratake, Tatsuaki Daimon, Ayako Nakashoji, Hiroki Ozawa, Bo Peng, Wei Li, Donald Kufe   +8 more
doaj   +1 more source

Long noncoding RNA XIST promotes cell proliferation and migration in diabetic foot ulcers through the miR-126-3p/EGFR axis

Diabetology & Metabolic Syndrome
Background The prevalence of diabetic foot ulcers (DFUs) has caused serious harm to human health. To date, a highly effective treatment is lacking. Long noncoding RNA X-inactive specific transcript (lncRNA XIST) has been the subject of mounting research ...
Wangbing Hong, Zhenfang Xiong, Xin Wang, Xincheng Liao, Mingzhuo Liu, Zhengying Jiang, Dinghong Min, Jiaqi Li, Guanghua Guo, Zhonghua Fu   +9 more
doaj   +1 more source

X-inactive-specific transcript of peripheral blood cells is regulated by exosomal Jpx and acts as a biomarker for female patients with hepatocellular carcinoma

Therapeutic Advances in Medical Oncology, 2017
Background: Long noncoding ribonucleic acid (lncRNA) X-inactive-specific transcript (Xist) was reported to affect cell proliferation and metastasis in hepatocellular carcinoma (HCC).
Xiang Ma, Tingdong Yuan, Chao Yang, Zusen Wang, Yunjin Zang, Liqun Wu, Likun Zhuang   +6 more
doaj   +1 more source

Functional Characterization of Human LncRNA JPX [PDF]

, 2019
OF THE DISSERTATIONFunctional Characterization of Human LncRNA JPXByHeather KarnerDoctor of Philosophy in Biological SciencesUniversity of California, Irvine, 2019Assistant Professor Sha Sun, Chair Long noncoding RNAs are present in all eukaryotes, but ...
Karner, Heather
core   +1 more source

Developing a ceRNA-based lncRNA-miRNA-mRNA regulatory network to uncover roles in skeletal muscle development

Frontiers in Bioinformatics
The precise role of lncRNAs in skeletal muscle development and atrophy remain elusive. We conducted a bioinformatic analysis of 26 GEO datasets from mouse studies, encompassing embryonic development, postnatal growth, regeneration, cell proliferation ...
Wang Wenlun, Wang Wenlun, Yu Chaohang, Huang Yan, Li Wenbin, Zhou Nanqing, Hu Qianmin, Wu Shengcai, Yuan Qing, Yu Shirui, Zhang Feng, Zhu Lingyun   +11 more
doaj   +1 more source

Xist ribonucleoproteins promote female sex-biased autoimmunity

Autoimmune diseases disproportionately affect females more than males. The XX sex chromosome complement is strongly associated with susceptibility to autoimmunity.
Goldman, Daniel W.,, Sjöberg, Ronald, Chung, Lorinda S.,, Srinivasan, Suhas, Chang, Sarah, Sjöberg, Ronald,, Wutz, Anton,, Casey, Kerriann M., Belk, Julia A., Chang, Howard Y.,, Li, Rui,, Kraft, Katerina,, Chang, Sarah,, Feng, Allan, Chung, Lorinda S., Casey, Kerriann M.,, Srinivasan, Suhas,, Käller Lundberg, Emma,, Zhao, Yanding,, Petri, Michelle, Feng, Allan,, Zhao, Yanding, Dou, Diana R.,, Abe, Brian T.,, Hellström, Cecilia,, Petri, Michelle,, Chen, Derek C., Dou, Diana R., Fiorentino, David F.,, Utz, Paul J.,, Yu, Bingfei,, Abe, Brian T., Zhao, Yang,, Shah, Ami A.,, Goldman, Daniel W., Chen, Derek C.,, Li, Rui, Hellström, Ceke, Yu, Bingfei, Shah, Ami A., Belk, Julia A.,, Kraft, Katerina, Wutz, Anton, et al.   +43 more
core   +1 more source

Identification of a Xist silencing domain 1 by Tiling CRISPR [PDF]

, 2019
Despite the essential roles of long noncoding RNAs (lncRNAs) in development and disease, methods determine lncRNA cis-elements are lacking. Here, we developed a screening method named “Tiling CRISPR” to identify lncRNA functional domains.
Wang, Yang, Zhong, Yang, Zhou, Yingyao, Tanaseichuk, Olga, Wilkinson, Jeremy, Li, Zhizhong, Zhao, Jing Crystal   +6 more
core  

Transcription Factor ETS1 Promotes Glioma Cell Growth by Activating LncRNA XIST

Zhongliu Fangzhi Yanjiu
Objective To explore the biological function and downstream mechanism of ETS1 in glioma. Methods Bioinformatics and immunohistochemistry were used to analyze the differential expression characteristics of ETS1 in gliomas; qRT-PCR was employed to detect ...
LUO Ran, LUO Wenyi, LU Mingkai, ZHOU Meng, LIU Yanting, TIAN Chunlei   +5 more
doaj   +1 more source