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Non-coding RNAs (ncRNAs) have been considered as unimportant additions to the transcriptome. Yet, in light of numerous studies, it has become clear that ncRNAs play important roles in development, health and disease. Long-ignored, long non-coding RNAs (lncRNAs), ncRNAs made of more than 200 nucleotides have gained attention due to their involvement as ...
Lidia Borkiewicz +4 more
openaire +3 more sources
E2F1-induced lncRNA, EMSLR regulates lncRNA LncPRESS1 [PDF]
AbstractE2F1 induces hundreds of protein-coding genes influencing diverse signaling pathways but much less is known about its non-coding RNA targets. For identifying E2F1-dependent oncogenic long non-coding RNAs (lncRNAs), we carried out genome-wide transcriptome analysis and discovered an lncRNA, EMSLR, which is induced both in lung adenocarcinoma ...
Priyanka Priyanka +3 more
openaire +3 more sources
Vitamin D Reduces the Helper T Cells 17 (Th17) Differentiation in Patients with Ulcerative Colitis by Targeting Long Non-coding RNA (lncRNA) OIP5-AS1/miR-26a-5p/IL-6 Axis [PDF]
Background: Vitamin D has anti-inflammatory efficacy against ulcerative colitis (UC), however, the mechanism is yet little understood. Objective: To investigate the immunomodulatory effects of vitamin D against the UC, and to explore the potential ...
Chaohui Zhu +5 more
doaj +1 more source
Long non-coding RNA Panel on Prognosis of Glioma in Iranian Patients
Objective: Glioma is one of the most malignant brain tumors, accounting for about half of the gliomas that occur in central nervous system (CNS), originates from the glial tissue of the brain.
Sara Esmaeili +7 more
doaj +1 more source
LNCcation: lncRNA localization and function
Bridges et al. discuss current knowledge, lingering questions, and emerging themes surrounding lncRNA subcellular localization and its impact on cellular functions.
M. C. Bridges +2 more
semanticscholar +1 more source
Long noncoding RNAs (lncRNAs) are recently implicated in modifying immunology in colorectal cancer (CRC). Nevertheless, the clinical significance of immune-related lncRNAs remains largely unexplored.
Zaoqu Liu +10 more
semanticscholar +1 more source
Role of 8-autophagy-related long non-coding RNAs signature in prognosis for bladder cancer
Objective To explore the potential prognostic role and value of autophagy-related lncRNA risk prediction signature in patients with bladder cancer.
TONG Hang +7 more
doaj +1 more source
Tumor immune microenvironment lncRNAs [PDF]
AbstractLong non-coding ribonucleic acids (RNAs) (lncRNAs) are key players in tumorigenesis and immune responses. The nature of their cell type-specific gene expression and other functional evidence support the idea that lncRNAs have distinct cellular functions in the tumor immune microenvironment (TIME).
Eun-Gyeong Park +4 more
openaire +2 more sources
Background: Long non-coding RNAs (lncRNAs) have emerged as crucial regulators in various biological processes, including cancer development and progression.
Raha Nikanfar +6 more
doaj +1 more source
Identification of a lncRNA/circRNA-miRNA-mRNA ceRNA Network in Alzheimer's Disease
Background: Alzheimer’s disease (AD) occurs in the elderly and pre-elderly, characterized by decline of memory, cognitive dysfunction, impairment of learning capacity, and motor dysfunction.
Lining Su +3 more
doaj +1 more source

