Results 41 to 50 of about 103,530 (319)
Identification of Key Molecules and lncRNA-miRNA-mRNA ceRNA Network in Preeclampsia
Shu Luo,1,3 Lina Wang,3 Shuming Li,3 Hongwei Wang,2 Sujing Huang,2 Zhongxia Zhang,2 Ru Wang,2 Hongqiong Guan,3 Yuanhua Huang1,4 1Nanjing Medical University, Nanjing, Jiangsu, 211166, People’s Republic of China; 2Department of Obstetrics, the Second ...
Luo S+8 more
doaj
LncRNAs in ocular neovascularizations
The prevalence of eye diseases worldwide is dramatically increasing and represents a major concern in underdeveloped and developed regions. Ocular diseases, previously associated with a higher depression risk, also impose a substantial economic burden on affected families, thus early detection and/or accurate treatment in order to avoid and prevent ...
Min-Ting Chen, Yacouba Cissé, Lang Bai
openaire +4 more sources
In our study, we conducted circRNA expression profiling of Zhongwei goat skin exhibiting divergent curvature wool phenotypes at two developmental stages using the RNA‐seq. Functional verification assay demonstrated that circRNA8782 regulated fibroblast proliferation.
Yingxiao Su+9 more
wiley +1 more source
Zhen Wang,* Huilin Yan,* Dingcai Cheng, Lei Xu, Tianming Shen, Yi Chen, Rongbo Han, Yanshi Xue Department of Urology, Taixing People’s Hospital, Taixing City, 225400, Jiangsu Province, People’s Republic of China*These authors contributed ...
Wang Z+7 more
doaj
PLIT: An alignment-free computational tool for identification of long non-coding RNAs in plant transcriptomic datasets [PDF]
Long non-coding RNAs (lncRNAs) are a class of non-coding RNAs which play a significant role in several biological processes. RNA-seq based transcriptome sequencing has been extensively used for identification of lncRNAs. However, accurate identification of lncRNAs in RNA-seq datasets is crucial for exploring their characteristic functions in the genome
arxiv +1 more source
LncRNA, miRNA and lncRNA-miRNA interaction in viral infection
Noncoding RNAs (ncRNAs) are key components of the transcriptome and play an important role in both normal biological activity and pathological processes such as viral infection and tumorigenesis. LncRNAs and miRNAs are the most important elements of ncRNAs and function as vital regulatory elements.
Linlin Chen, Hongjun Li, Yan Zhou
openaire +2 more sources
Interplay between lncRNA/miRNA and Wnt/β-catenin signaling in brain cancer tumorigenesis
Brain cancers are among the most aggressive malignancies with high mortality and morbidity worldwide. The pathogenesis of brain cancers is a very complicated process involving various genetic mutations affecting several oncogenic signaling pathways like ...
Farzad Rahmani+8 more
doaj +1 more source
DeepHEN: quantitative prediction essential lncRNA genes and rethinking essentialities of lncRNA genes [PDF]
Gene essentiality refers to the degree to which a gene is necessary for the survival and reproductive efficacy of a living organism. Although the essentiality of non-coding genes has been documented, there are still aspects of non-coding genes' essentiality that are unknown to us.
arxiv
The lncRNA epigenetics: The significance of m6A and m5C lncRNA modifications in cancer
Most of our transcribed RNAs are represented by non-coding sequences. Long non-coding RNAs (lncRNAs) are transcripts with no or very limited protein coding ability and a length >200nt. They can be epigenetically modified. N6-methyladenosine (m6A), N1-methyladenosine (m1A), 5-methylcytosine (m5C), 7-methylguanosine (m7G) and 2’-O-methylation (Nm)
Vincenza Ylenia Cusenza+3 more
openaire +3 more sources
Xiao-Yu Yan, 1,* Juan-Juan Zhang, 2,* Xin-Ru Zhong, 1 Si-Hang Yu, 1 Long Xu, 1 Rui Tian, 1 Lian-Kun Sun, 1 Jing Su 1 1Key Laboratory of Pathobiology, Ministry of Education, Department of Pathophysiology, College of Basic Medical Sciences, Jilin ...
Yan XY+7 more
doaj