Results 101 to 110 of about 76,795 (267)
Animal Research and One Health, EarlyView.This study identified a molecule named lncRSFD, which is highly expressed in sheep adipose tissues. The lncRSFD gene generates two distinct transcript variants via alternative splicing: lncRSFD‐L and lncRSFD‐S. Functionally, lncRSFD alternative splicing (lncRSFD‐L/S) promotes the proliferation, differentiation, and lipid metabolism of adipocytes ...
Jinpeng Wang +9 more
wiley +1 more source
Exosomal Long Non-Coding RNA Expression from Serum of Patients with Acute Minor Stroke
Neuropsychiatric Disease and Treatment, 2020 Xiaonan Xu, 1,* Chengle Zhuang, 2,* Liming Chen 1 1Department of Neurology, Shenzhen University General Hospital, Shenzhen 518000, Guangdong Province, People’s Republic of China; 2Department of Urology, Peking University Shenzhen Hospital ...
Xu X, Zhuang C, Chen L
doaj
Arthritis &Rheumatology, EarlyView.Objective Dermal systemic sclerosis (SSc) fibroblasts and their exosomes can activate keratinocytes in SSc, with long noncoding RNA (lncRNA) H19 highlighted as the most up‐regulated RNA in their cargo compared with healthy controls (HCs). The role of H19 in SSc pathogenesis has never been investigated.
Begoña Caballero‐Ruiz +3 more
wiley +1 more source
Biotechnology and Bioengineering, EarlyView.ABSTRACT Extracellular vesicles (EVs) are nanoscale membrane‐bound structures that play a pivotal role in intercellular communication by transporting bioactive molecules, including proteins, lipids, nucleic acids, and organelles, between cells. Originating from the endosomal pathway, EVs reflect the physiological and pathological status of their parent
Emine İncilay Torunoğlu +3 more
wiley +1 more source
Coordinated regulation by lncRNAs results in tight lncRNA-target couplings
Cell GenomicsThe determination of long non-coding RNA (lncRNA) function is a major challenge in RNA biology with applications to basic, translational, and medical research. We developed BigHorn to computationally infer lncRNA-DNA interactions that mediate transcription and chromatin-remodeling factor activity.
Hua-Sheng Chiu +23 more
openaire +3 more sources
Biological Reviews, EarlyView.ABSTRACT The complexity of breast cancer (BC) lung metastasis lies in the capacity of tumour cells to interact efficiently with distant organs to promote colonisation, a process that involves the sophisticated coordination of inherent cellular plasticity and the remodelling of the distant microenvironment.
Jian Lu +12 more
wiley +1 more source
Cancer Management and Research, 2020 Jianxin Jiang,* Xiaolin Wang,* Jun Lu Department of Neurosurgery, Taizhou People’s Hospital, Taizhou, Jiangsu Province 225300, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jun LuDepartment of ...
Jiang J, Wang X, Lu J
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Cancer Management and Research, 2021 Lili Gao,* Qing Li* Department of Pathology, Pudong New Area People’s Hospital, Shanghai, People’s Republic of China*These authors contributed equally to this workCorrespondence: Lili Gao Email suhullg@163.comBackground: The role of ...
Gao L, Li Q
doaj
Oocyte–cumulus cell interaction: a key factor in early embryo development
Biological Reviews, EarlyView.ABSTRACT The evaluation of oocyte competence is a fundamental step in achieving successful outcomes following assisted reproduction techniques (ART). At present, however, conventional oocyte maturation assessment is carried out by morphological observation, which is a subjective method that does not consider molecular features.
Marc Torres‐Garrido +2 more
wiley +1 more source
Cancer Nexus, EarlyView.ABSTRACT In this study, we identified gene modules and representative candidate biomarkers linked to clinical progression in patients with UBC. Weighted gene co‐expression network analysis (WGCNA) was used to identify gene modules associated with TNM staging in UBC patients.
Arshia Azmoudeh
wiley +1 more source