Results 11 to 20 of about 252,842 (294)
Molecules, 2022 TWIK-related acid-sensitive K+ (TASK) channels, including TASK-1, TASK-3, and TASK-5, are important members of the two-pore domain potassium (K2P) channel family. TASK-5 is not functionally expressed in the recombinant system.
Xueming Fan +3 more
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Structural Modification in Anesthetic Drug Development for Prodrugs and Soft Drugs
Frontiers in Pharmacology, 2022 Among the advancements in drug structural modifications, the increased focus on drug metabolic and pharmacokinetic properties in the anesthetic drug design process has led to significant developments.
Chaoyi Deng +5 more
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Frontiers in Microbiology, 2023 BackgroundPrevious studies have implicated a vital association between gut microbiota/gut microbial metabolites and low back pain (LBP), but their causal relationship is still unclear.
Mengchan Su +8 more
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Enhanced Antitumor Activity of Lidocaine Nanoparticles Encapsulated by a Self-Assembling Peptide
Frontiers in Pharmacology, 2022 Although local anesthetics (LAs) such as lidocaine have been traditionally used for pain relief, their antitumor activity has attracted more and more attentions in recent years.
Yang Yang +13 more
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Multisite chronic pain and the risk of autoimmune diseases: A Mendelian randomization study
Frontiers in Immunology, 2023 BackgroundAccumulating evidence has demonstrated that an association between chronic pain and autoimmune diseases (AIDs). Nevertheless, it is unclear whether these associations refer to a causal relationship. We used a two-sample Mendelian randomization (
Yidan Tang +8 more
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Effects of Perioperative Epidural Analgesia on Cancer Recurrence and Survival
Frontiers in Oncology, 2022 Surgical resection is the main curative avenue for various cancers. Unfortunately, cancer recurrence following surgery is commonly seen, and typically results in refractory disease and death.
Donghang Zhang +7 more
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Brain Sciences, 2023 Astrocytes are morphologically intricate cells and actively modulate the function of the brain. Through numerous fine processes, astrocytes come into contact with neurons, blood vessels, and other glia cells.
Qingran Li +8 more
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Frontiers in Pharmacology, 2021 Background: ET-26 hydrochloride (ET-26HCl), a class 1 new drug, was developed to reserve the advantages of etomidate with a mild adrenocortical inhibition.Purpose: this study was to evaluate the potential adverse effects on the cardiovascular system of ...
YuJun Zhang +17 more
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Ropivacaine as the drug of choice for regional anesthesia: why so?
Медицина болю, 2021 While writing the article, we analyzed all the studies related to ropivacaine for the first half of 2021, which were published in PubMed. Previous review articles on ropivacaine were also analyzed.
Dmytro Dmytriiev, Yevhen Lisak
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