Results 11 to 20 of about 5,302,191 (386)
The Thermodynamics of General and Local Anesthesia [PDF]
General anesthetics are known to cause depression of the freezing point of transitions in biomembranes. This is a consequence of ideal mixing of the anesthetic drugs in the membrane fluid phase and exclusion from the solid phase. Such a generic law provides physical justification of the famous Meyer-Overton rule.
Graesboll, Kaare+2 more
openaire +7 more sources
BackgroundAlthough well-documented, the causal relationships between diet-derived circulating antioxidants, oxidative stress, and osteoarthritis (OA) are equivocal.
Yidan Tang+10 more
doaj +1 more source
General Versus Local Anesthesia With Conscious Sedation in Transcatheter Aortic Valve Implantation
Background: In clinical practice, local anesthesia with conscious sedation (CS) is performed in roughly 50% of patients undergoing transcatheter aortic valve replacement.
H. Thiele+33 more
semanticscholar +1 more source
The feasibility of local anesthesia for the surgical treatment of umbilical hernia: a systematic review of the literature [PDF]
Background: Yearly approximately 4500 umbilical hernias are repaired in The Netherlands, mostly under general anesthesia. The use of local anesthesia has shown several advantages in groin hernia surgery.
Jairam, A.P. (An)+4 more
core +8 more sources
History of anesthesia usage in dentistry [PDF]
Since prehistoric times, man has sought ways to lessen pain. With varying degrees of success he has utilized: opium, nerve compresses, cold, hypnosis, etc.
Koković Vladimir
doaj +1 more source
TWIK-related acid-sensitive K+ (TASK) channels, including TASK-1, TASK-3, and TASK-5, are important members of the two-pore domain potassium (K2P) channel family. TASK-5 is not functionally expressed in the recombinant system.
Xueming Fan+3 more
doaj +1 more source
Dissolving Microneedles for Rapid and Painless Local Anesthesia
Microneedles are emerging drug delivery methods for painless treatment. The current study tested dissolving microneedles containing lidocaine (Li-DMN) for use in local anesthesia.
Byeong-min Lee+5 more
semanticscholar +1 more source
An on-demand anesthetic that would only take effect when needed and where the intensity of anesthesia could be easily adjustable according to patients’ needs would be highly desirable.
Wei Zhang+7 more
semanticscholar +1 more source
Structural Modification in Anesthetic Drug Development for Prodrugs and Soft Drugs
Among the advancements in drug structural modifications, the increased focus on drug metabolic and pharmacokinetic properties in the anesthetic drug design process has led to significant developments.
Chaoyi Deng+5 more
doaj +1 more source
BackgroundPrevious studies have implicated a vital association between gut microbiota/gut microbial metabolites and low back pain (LBP), but their causal relationship is still unclear.
Mengchan Su+8 more
doaj +1 more source