Results 11 to 20 of about 5,332,407 (361)

Brachial Plexus Nerve Trunk Segmentation Using Deep Learning: A Comparative Study with Doctors' Manual Segmentation [PDF]

[J]. Ultrasound in Medicine & Biology, 2024, 50(3): 374-383, 2022
Ultrasound-guided nerve block anesthesia (UGNB) is a high-tech visual nerve block anesthesia method that can observe the target nerve and its surrounding structures, the puncture needle's advancement, and local anesthetics spread in real-time. The key in UGNB is nerve identification.
arxiv   +1 more source

General anesthesia versus local anesthesia for penetrating keratoplasty:a prospective study [PDF]

International Journal of Ophthalmology, 2014
AIM:To examine which anesthesia general or local is more effective for penetrating keratoplasty (PKP).METHODS: Patients with indications for PKP (n=141) were enrolled in a prospective study and randomly divided into general anesthesia group (group A, 70 ...
Xu Wang, Guang-Fu Dang, Ying-Mei Li, Wei-Fan Li, Xin-Yi Wu   +4 more
doaj   +1 more source

The volatile anesthetic isoflurane differentially inhibits voltage-gated sodium channel currents between pyramidal and parvalbumin neurons in the prefrontal cortex

Frontiers in Neural Circuits, 2023
BackgroundHow volatile anesthetics work remains poorly understood. Modulations of synaptic neurotransmission are the direct cellular mechanisms of volatile anesthetics in the central nervous system.
Jingxuan Qiu, Jingxuan Qiu, Yaoxin Yang, Yaoxin Yang, Jin Liu, Wenling Zhao, Qian Li, Qian Li, Tao Zhu, Peng Liang, Cheng Zhou   +10 more
doaj   +1 more source

Genetic liability for diet-derived circulating antioxidants, oxidative stress, and risk of osteoarthritis: a Mendelian randomization study

Frontiers in Nutrition, 2023
BackgroundAlthough well-documented, the causal relationships between diet-derived circulating antioxidants, oxidative stress, and osteoarthritis (OA) are equivocal.
Yidan Tang, Yidan Tang, Xiaolin Xu, Xiaolin Xu, Shuangyi Zhang, Shuangyi Zhang, Weishuang Kong, Weiyi Zhang, Weiyi Zhang, Tao Zhu, Tao Zhu   +10 more
doaj   +1 more source

General Versus Local Anesthesia With Conscious Sedation in Transcatheter Aortic Valve Implantation

Circulation, 2020
Background: In clinical practice, local anesthesia with conscious sedation (CS) is performed in roughly 50% of patients undergoing transcatheter aortic valve replacement.
H. Thiele, T. Kurz, H. Feistritzer, G. Stachel, P. Hartung, P. Lurz, I. Eitel, C. Marquetand, H. Nef, O. Doerr, U. Vigelius-Rauch, A. Lauten, U. Landmesser, S. Treskatsch, M. Abdel-Wahab, M. Sandri, D. Holzhey, M. Borger, J. Ender, H. Ince, A. Öner, R. Meyer‐Saraei, R. Hambrecht, A. Fach, T. Augenstein, N. Frey, I. König, R. Vonthein, Yvonne Rückert, A. Funkat, S. Desch, Astrid E. Berggreen, M. Heringlake, S. de Waha‐Thiele   +33 more
semanticscholar   +1 more source

History of anesthesia usage in dentistry [PDF]

Stomatološki glasnik Srbije, 2005
Since prehistoric times, man has sought ways to lessen pain. With varying degrees of success he has utilized: opium, nerve compresses, cold, hypnosis, etc.
Koković Vladimir
doaj   +1 more source

Dissolving Microneedles for Rapid and Painless Local Anesthesia

Pharmaceutics, 2020
Microneedles are emerging drug delivery methods for painless treatment. The current study tested dissolving microneedles containing lidocaine (Li-DMN) for use in local anesthesia.
Byeong-min Lee, Chisong Lee, S. F. Lahiji, U. Jung, G. Chung, Hyungil Jung   +5 more
semanticscholar   +1 more source

Advances in the Understanding of Two-Pore Domain TASK Potassium Channels and Their Potential as Therapeutic Targets

Molecules, 2022
TWIK-related acid-sensitive K+ (TASK) channels, including TASK-1, TASK-3, and TASK-5, are important members of the two-pore domain potassium (K2P) channel family. TASK-5 is not functionally expressed in the recombinant system.
Xueming Fan, Yongzhi Lu, Guizhi Du, Jin Liu   +3 more
doaj   +1 more source

Light-triggered release of conventional local anesthetics from a macromolecular prodrug for on-demand local anesthesia

Nature Communications, 2020
An on-demand anesthetic that would only take effect when needed and where the intensity of anesthesia could be easily adjustable according to patients’ needs would be highly desirable.
Wei Zhang, T. Ji, Yang Li, Yueqin Zheng, Manisha Mehta, Chao Zhao, Andong Liu, D. Kohane   +7 more
semanticscholar   +1 more source

Structural Modification in Anesthetic Drug Development for Prodrugs and Soft Drugs

Frontiers in Pharmacology, 2022
Among the advancements in drug structural modifications, the increased focus on drug metabolic and pharmacokinetic properties in the anesthetic drug design process has led to significant developments.
Chaoyi Deng, Chaoyi Deng, Jin Liu, Jin Liu, Wensheng Zhang, Wensheng Zhang   +5 more
doaj   +1 more source