Results 11 to 20 of about 5,211,551 (359)
Frontiers in Neural Circuits, 2023 BackgroundHow volatile anesthetics work remains poorly understood. Modulations of synaptic neurotransmission are the direct cellular mechanisms of volatile anesthetics in the central nervous system.
Jingxuan Qiu +10 more
doaj +1 more source
General Versus Local Anesthesia With Conscious Sedation in Transcatheter Aortic Valve Implantation
Circulation, 2020 Background: In clinical practice, local anesthesia with conscious sedation (CS) is performed in roughly 50% of patients undergoing transcatheter aortic valve replacement.
H. Thiele +33 more
semanticscholar +1 more source
Dissolving Microneedles for Rapid and Painless Local Anesthesia
Pharmaceutics, 2020 Microneedles are emerging drug delivery methods for painless treatment. The current study tested dissolving microneedles containing lidocaine (Li-DMN) for use in local anesthesia.
Byeong-min Lee +5 more
semanticscholar +1 more source
History of anesthesia usage in dentistry [PDF]
Stomatološki glasnik Srbije, 2005 Since prehistoric times, man has sought ways to lessen pain. With varying degrees of success he has utilized: opium, nerve compresses, cold, hypnosis, etc.
Koković Vladimir
doaj +1 more source
Molecules, 2022 TWIK-related acid-sensitive K+ (TASK) channels, including TASK-1, TASK-3, and TASK-5, are important members of the two-pore domain potassium (K2P) channel family. TASK-5 is not functionally expressed in the recombinant system.
Xueming Fan +3 more
doaj +1 more source
Nature Communications, 2020 An on-demand anesthetic that would only take effect when needed and where the intensity of anesthesia could be easily adjustable according to patients’ needs would be highly desirable.
Wei Zhang +7 more
semanticscholar +1 more source
Effectiveness of local and topical anesthesia during gingival retraction
Brazilian Dental Science, 2022 Objective: To compare the effectiveness of local and topical anesthesia during gingival retraction in prepared abutment teeth. Material and Methods: 72 patients desiring full mouth rehabilitation or bilateral fixed partial denture in the same arch were ...
Aman Merchant +2 more
semanticscholar +1 more source
Structural Modification in Anesthetic Drug Development for Prodrugs and Soft Drugs
Frontiers in Pharmacology, 2022 Among the advancements in drug structural modifications, the increased focus on drug metabolic and pharmacokinetic properties in the anesthetic drug design process has led to significant developments.
Chaoyi Deng +5 more
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Frontiers in Microbiology, 2023 BackgroundPrevious studies have implicated a vital association between gut microbiota/gut microbial metabolites and low back pain (LBP), but their causal relationship is still unclear.
Mengchan Su +8 more
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Development of Lidocaine-Loaded Dissolving Microneedle for Rapid and Efficient Local Anesthesia
Pharmaceutics, 2020 Lidocaine is a local anesthetic agent used in the form of injection and topical cream. However, these formulation types have limitations of being either painful or slow-acting, thereby hindering effective and complete clinical performance of lidocaine ...
Huisuk Yang +12 more
semanticscholar +1 more source