Results 1 to 10 of about 885,184 (197)
Stent development and local drug delivery [PDF]
British Medical Bulletin, 2001 Stent implantation has become the new standard angioplasty procedure. Instent re-stenosis remains the major limitation of coronary stenting. Re-stenosis is related to patient-, lesion- and procedure-specific factors.
Regar, E.S. (Eveline) +2 more
core +14 more sources
Local Drug Delivery in Bladder Cancer: Advances of Nano/Micro/Macro-Scale Drug Delivery Systems [PDF]
Pharmaceutics, 2023 Treatment of bladder cancer remains a critical unmet need and requires advanced approaches, particularly the development of local drug delivery systems. The physiology of the urinary bladder causes the main difficulties in the local treatment of bladder ...
Irina V. Marchenko, Daria B. Trushina
doaj +2 more sources
Bioadhesive Nanoparticles for Local Drug Delivery [PDF]
International Journal of Molecular Sciences, 2022 Local drug delivery is an effective strategy for achieving direct and instant therapeutic effects. Current clinical treatments have fallen short and are limited by traditional technologies. Bioadhesive nanoparticles (NPs), however, may be a promising carrier for optimized local drug delivery, offering prolonged drug retention time and steadily ...
Yu, Liu +8 more
exaly +3 more sources
Local Drug Delivery Strategies towards Wound Healing [PDF]
Pharmaceutics, 2023 A particular biological process known as wound healing is connected to the overall phenomena of growth and tissue regeneration. Several cellular and matrix elements work together to restore the integrity of injured tissue.
Ruchi Tiwari, Kamla Pathak
doaj +2 more sources
Pre-clinical investigation of liquid sirolimus for local drug delivery [PDF]
Frontiers in Cardiovascular Medicine, 2023 IntroductionSirolimus is currently being explored as an alternative drug to paclitaxel for the treatment of peripheral artery disease (PAD). To date, sirolimus has only been used as drug coatings for stents and balloons and no studies have yet ...
Meagan Todd +3 more
doaj +2 more sources
Nanoscale systems for local drug delivery
Nano Today, 2019 Many diseases and conditions affect a relatively localized area of the body. They can be treated either by direct deposition of drug in the target area, or by giving the drug systemically. Here we review nanoparticle-based approaches to achieving both.
Tianjiao Ji, Daniel S Kohane
exaly +4 more sources
Editorial on Special Issue “Lipid Nanosystems for Local Drug Delivery” [PDF]
Pharmaceutics, 2023 Nanosystems provide an attractive approach to pharmacological therapy, with the possibility of enhancing the performance and overcoming the constraints of conventional therapies, thus adding substantial value to some of the already available formulations
José Catita, Carla M. Lopes
doaj +2 more sources
Construction of Local Drug Delivery System on Titanium-Based Implants to Improve Osseointegration
Pharmaceutics, 2022 Titanium and its alloys are the most widely applied orthopedic and dental implant materials due to their high biocompatibility, superior corrosion resistance, and outstanding mechanical properties.
Fanying Meng +4 more
doaj +3 more sources
Local Drug Delivery for the Treatment of Neurotology Disorders [PDF]
Frontiers in Cellular Neuroscience, 2019 Neurotology disorders such as vertigo, tinnitus, and hearing loss affect a significant proportion of the population (estimated 39 million in the United States with moderate to severe symptoms).
Fabrice Piu, Kathie M. Bishop
doaj +3 more sources
Local Drug Delivery Strategies for Glioblastoma Treatment. [PDF]
Brain Tumor Res Treat, 2022 Glioblastoma multiforme (GBM) is a brain tumor notorious for its malignancy. The key reason for the limited efficacy of standard treatment is the high recurrence rate of GBM, even after surgical resection. Hence, intensive postsurgical chemical therapies, such as the systemic delivery of various drugs and/or drug combinations, are typically followed ...
Cha GD, Jung S, Choi SH, Kim DH.
europepmc +3 more sources