Results 21 to 30 of about 10,043,064 (337)

Hydrogel-based local drug delivery strategies for spinal cord repair

open access: yesNeural Regeneration Research, 2021
Spinal cord injury results in significant loss of motor, sensory, and autonomic functions. Although a wide range of therapeutic agents have been shown to attenuate secondary injury or promote regeneration/repair in animal models of spinal cord injury ...
Robert B Shultz, Yinghui Zhong
doaj   +2 more sources

Local Drug Delivery for Prevention of Hearing Loss

open access: yesFrontiers in Cellular Neuroscience, 2019
Systemic delivery of therapeutics for targeting the cochlea to prevent or treat hearing loss is challenging. Systemic drugs have to cross the blood-labyrinth barrier (BLB).
Leonard P. Rybak   +4 more
doaj   +2 more sources

Editorial on Special Issue “Lipid Nanosystems for Local Drug Delivery” [PDF]

open access: yesPharmaceutics, 2023
Nanosystems provide an attractive approach to pharmacological therapy, with the possibility of enhancing the performance and overcoming the constraints of conventional therapies, thus adding substantial value to some of the already available formulations
José Catita, Carla M. Lopes
doaj   +2 more sources

A pH-Responsive Ti-Based Local Drug Delivery System for Osteosarcoma Therapy [PDF]

open access: yesJournal of Functional Biomaterials
Osteosarcoma is one of the major bone cancers, especially for youngsters. The current treatment usually requires systemic chemotherapy and the removal of bone tumors.
Qinle Xiao   +6 more
doaj   +2 more sources

Doxycycline Proniosomal Gel as Local Drug Delivery System in Periodontal Disease: A Vitro Study

open access: yesJournal of Pharmacy and Bioallied Sciences
Background: Periodontitis is an inflammatory condition of the oral cavity in which microorganisms play a significant role in the pathogenesis and onset.
Dhawal Rajendra Mody   +4 more
doaj   +2 more sources

Local Drug Delivery by Microbubbles [PDF]

open access: yes, 2020
The aim of this thesis was to unravel the microbubble-cell interaction required for local drug delivery. By developing methodological innovations for novel in vitro studies, the underlying biophysical mechanisms of ultrasound-mediated drug delivery ...
Beekers, Inés, Beekers, I. (Inés)
openaire   +2 more sources

Guidelines for the application of 3D printing in the field of medical devices

open access: yesJournal of Holistic Integrative Pharmacy, 2021
This paper briefly summarizes the regulatory laws and regulations for customized additive manufacturing medical devices in China, the United States, and Canada.
ZHANG Wenfang   +5 more
doaj   +1 more source

Recent progress of hydrogel-based local drug delivery systems for postoperative radiotherapy

open access: yesFrontiers in Oncology, 2023
Surgical resection and postoperative radiotherapy remained the most common therapeutic modalities for malignant tumors. However, tumor recurrence after receiving such combination is difficult to be avoided because of high invasiveness and radiation ...
Yan-Dong Xie   +8 more
semanticscholar   +1 more source

Impact of local drug delivery and natural agents as new target strategies against periodontitis: new challenges for personalized therapeutic approach

open access: yesTherapeutic Advances in Chronic Disease, 2023
Periodontitis is a persistent inflammation of the soft tissue around the teeth that affects 60% of the population in the globe. The self-maintenance of the inflammatory process can cause periodontal damage from the alveolar bone resorption to tooth loss ...
G. Viglianisi   +6 more
semanticscholar   +1 more source

Local Drug Delivery to Treat Chronic Periodontitis

open access: yesJournal of Bahria University Medical and Dental College, 2021
Periodontal disease is a chronic inflammatory disease of periodontium characterized by increased pocket depth, clinical attachment loss, sulcular bleeding, and bone loss. Bacterial plaque bio-film stimulates host derived enzymes and cytokines like TNF ,
Mamoora Arslaan   +3 more
doaj   +1 more source

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