Stimuli-Responsive Hydrogels for Local Post-Surgical Drug Delivery
Gels, 2020 Currently, surgical operations, followed by systemic drug delivery, are the prevailing treatment modality for most diseases, including cancers and trauma-based injuries. Although effective to some extent, the side effects of surgery include inflammation,
Esfandyar Askari +7 more
doaj +1 more source
Turmeric as a local drug delivery in periodontitis: A review of literature
CHRISMED Journal of Health and Research, 2022 Periodontitis is a multifactorial disease. Traditional methods like toothbrushing and manual scaling and root planing are the treatment of choice. However, these methods are time-consuming and not fully effective.
Arnav Mukherji, Sinthiya Bose
doaj +1 more source
The optimized drug delivery systems of treating cancer bone metastatic osteolysis with nanomaterials
Drug Delivery, 2021 Some cancers such as human breast cancer, prostate cancer, and lung cancer easily metastasize to bone, leading to osteolysis and bone destruction accompanied by a complicated microenvironment.
Xi Cheng +6 more
doaj +1 more source
Novel Therapeutic Approach for the Treatment of Periodontitis by Curcumin [PDF]
Journal of Clinical and Diagnostic Research, 2014 Aims and objectives: The aim of the present study was to evaluate the clinical and microbiological efficacy of locally delivered 1% curcumin gel as an adjunct to scaling and root planing in the treatment of chronic periodontitis.
Madhu Bhatia +5 more
doaj +1 more source
Solid Lipid Nanoparticles: A Potential Approach for Dermal Drug Delivery [PDF]
, 2014 Solid lipid nanoparticles (SLNs) have attracted increasing attention during recent years. Due to their unique size dependent properties, lipid nanoparticles offer possibilities to develop new therapeutics.
Conway, Barbara R, Kakadia, Pratibha G.
core +1 more source
Local drug delivery to prevent restenosis [PDF]
Journal of Vascular Surgery, 2013 Despite significant advances in vascular biology, bioengineering, and pharmacology, restenosis remains a limitation to the overall efficacy of vascular reconstructions, both percutaneous and open. Although the pathophysiology of intimal hyperplasia is complex, a number of drugs and molecular tools have been identified that can prevent restenosis ...
Seedial, Stephen M. +6 more
openaire +2 more sources
Evaluation of Drug Delivery and Efficacy of Ciprofloxacin-Loaded Povidone Foils and Nanofiber Mats in a Wound-Infection Model Based on Ex Vivo Human Skin [PDF]
, 2019 Topical treatment of wound infections is often a challenge due to limited drug availability at the site of infection. Topical drug delivery is an attractive option for reducing systemic side effects, provided that a more selective and sustained local ...
Bayer, Ilker S. +6 more
core +2 more sources
Modulation of release kinetics by plasma polymerization of ampicillin-loaded ß-TCP ceramics [PDF]
, 2016 Beta-tricalcium phosphate (ß-TCP) bioceramics are employed in bone repair surgery. Their local implantation in bone defects puts them in the limelight as potential materials for local drug delivery.
Avilés, Marc +4 more
core +2 more sources
Influence of excipients on spray-dried powders for inhalation [PDF]
, 2014 Two areas attracting considerable attention when developing effective pulmonary drug delivery systems include the improvement of aerosolisation efficiency of the inhaled formulation and the controlled release of drug from the formulation following ...
Adi +45 more
core +1 more source
Hydrogel-based local drug delivery strategies for spinal cord repair
Neural Regeneration Research, 2021 Spinal cord injury results in significant loss of motor, sensory, and autonomic functions. Although a wide range of therapeutic agents have been shown to attenuate secondary injury or promote regeneration/repair in animal models of spinal cord injury ...
Robert B Shultz, Yinghui Zhong
doaj +1 more source