Results 11 to 20 of about 885,184 (197)

A pH-Responsive Ti-Based Local Drug Delivery System for Osteosarcoma Therapy [PDF]

Journal of Functional Biomaterials
Osteosarcoma is one of the major bone cancers, especially for youngsters. The current treatment usually requires systemic chemotherapy and the removal of bone tumors.
Qinle Xiao, Changjun Wan, Zhe Zhang, Hui Liu, Pingting Liu, Qianli Huang, Dapeng Zhao   +6 more
doaj   +2 more sources

Doxycycline Proniosomal Gel as Local Drug Delivery System in Periodontal Disease: A Vitro Study

Journal of Pharmacy and Bioallied Sciences
Background: Periodontitis is an inflammatory condition of the oral cavity in which microorganisms play a significant role in the pathogenesis and onset.
Dhawal Rajendra Mody, Vrushali Lathiya, Abhay P. Kolte, Vaishnavi Biradar, Vaishnavi Langde   +4 more
doaj   +2 more sources

Guidelines for the application of 3D printing in the field of medical devices

Journal of Holistic Integrative Pharmacy, 2021
This paper briefly summarizes the regulatory laws and regulations for customized additive manufacturing medical devices in China, the United States, and Canada.
ZHANG Wenfang, MOU Hongli, KUANG Xiaoying, LUO Huiyan, YANG Fan, HUANG Siyu   +5 more
doaj   +1 more source

Local Drug Delivery to Treat Chronic Periodontitis

Journal of Bahria University Medical and Dental College, 2021
Periodontal disease is a chronic inflammatory disease of periodontium characterized by increased pocket depth, clinical attachment loss, sulcular bleeding, and bone loss. Bacterial plaque bio-film stimulates host derived enzymes and cytokines like TNF ,
Mamoora Arslaan, Nasim Karim, Wahab Baksh Kadri, Shama Asghar   +3 more
doaj   +1 more source

Oleogel-based drug delivery for the treatment of periodontitis: current strategies and future perspectives [version 1; peer review: 2 approved]

F1000Research, 2023
Periodontitis is the chronic inflammation of tooth-supporting tissues that leads to loss of tooth support if untreated. Conventional therapy for periodontitis (mechanical removal of microbial biofilm and oral hygiene enforcement) is augmented by anti ...
Shashikiran Shanmugasundaram, Baishakhi Modak, Shaswata Karmakar   +2 more
doaj   +1 more source

Multifunctional nanocarriers for lung drug delivery [PDF]

, 2020
Nanocarriers have been increasingly proposed for lung drug delivery applications. The strategy of combining the intrinsic and more general advantages of the nanostructures with specificities that improve the therapeutic outcomes of particular clinical ...
Grenha, Ana, Pontes, Jorge Filipe
core   +2 more sources

Injectable DNA Hydrogel-Based Local Drug Delivery and Immunotherapy

Gels, 2022
Regulated drug delivery is an important direction in the field of medicine and healthcare research. In recent years, injectable hydrogels with good biocompatibility and biodegradability have attracted extensive attention due to their promising ...
Qi Wang, Yanfei Qu, Ziyi Zhang, Hao Huang, Yufei Xu, Fengyun Shen, Lihua Wang, Lele Sun   +7 more
doaj   +1 more source

Local drug delivery drugs and systems [PDF]

International Journal of Applied Dental Sciences, 2020
Periodontal disease is a multifactorial disease that affects the supporting tissues resulting in destruction of supporting structure. Non surgical periodontal treatment has been a cornerstone in the management of periodontics. Local drug delivery system is the application of anti microbial or anti infective agent that would target pathogenic micro ...
Dr. Uma Sudhakar, K Ruth Gethsie, H Priyanka, SS Fathima Zinneerah   +3 more
openaire   +1 more source

Transdermal drug delivery by localized intervention [PDF]

IEEE Engineering in Medicine and Biology Magazine, 2009
Both field-confined skin electroporation and microscissioning offer minimally invasive methods for delivering drugs across skin and nail with minimal sensation. Both methods create high permeability pathways in a pain-free manner. These openings are similar in dimension to commonly experienced scratches and nicks on the skin.
Weaver, James C., Herndon, Terry O., Gowrishankar, Thiruvallur R.   +2 more
openaire   +3 more sources

Local Delivery of Therapeutics to the Cochlea Using Nanoparticles and Other Biomaterials

Pharmaceuticals, 2022
Hearing loss negatively impacts the well-being of millions of people worldwide. Systemic delivery of ototherapeutics has limited efficacy due to severe systemic side effects and the presence of the blood–labyrinth barrier that selectively limits or ...
Shreshtha Dash, Jian Zuo, Peter S. Steyger   +2 more
doaj   +1 more source