Results 41 to 50 of about 11,319,078 (248)
RNA:protein ratio of the unicellular organism as a characteristic of phosphorous and nitrogen stoichiometry and of the cellular requirement of ribosomes for protein synthesis [PDF]
, 2006 Background Mean phosphorous:nitrogen (P:N) ratios and relationships of P:N ratios with the growth rate of organisms indicate a surprising similarity among and within microbial species, plants, and insect herbivores.
Karpinets, Tatiana V. +8 more
core +1 more source
Nature Communications, 2023 The neuronal RNA-binding protein Ptbp2 regulates neuronal differentiation by modulating alternative splicing programs in the nucleus. Such programs contribute to axonogenesis by adjusting the levels of protein isoforms involved in axon growth and ...
Saeede Salehi +9 more
doaj +1 more source
Local Translation in Nervous System Pathologies
Frontiers in Integrative Neuroscience, 2021 Dendrites and axons can extend dozens to hundreds of centimeters away from the cell body so that a single neuron can sense and respond to thousands of stimuli.
María Gamarra +9 more
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Frontiers in Molecular NeuroscienceThe neurotrophin brain-derived neurotrophic factor (BDNF) plays a key role in neuronal development and synaptic plasticity. The discovery that BDNF mRNA can be transported in neuronal dendrites in an activity-dependent manner has suggested that its local
Giorgia Bimbi, Enrico Tongiorgi
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MATRIX platform to analyze translation machinery remodeling in glioblastoma cells
STAR Protocols, 2022 Summary: Here, we present a protocol using MATRIX (mass spectrometry analysis of active translation factors using ribosome density fractionation and isotopic labeling experiments) platform to investigate changes of the protein synthesis machinery in ...
J.J. David Ho +4 more
doaj +1 more source
Synthesis and subcellular localization of the murine coronavirus nucleocapsid protein
Virology, 1983 The synthesis and processing of the nucleocapsid protein (pp60) of the JHM strain of murine coronaviruses were examined. Pulse-chase experiments showed that pp60 was synthesized initially as a protein of approximately 57,000 in molecular weight (p57).
Stohlman, Stephen A. +3 more
openaire +2 more sources
Polysomal Localization of R17 Bacteriophage-Specific Protein Synthesis [PDF]
Journal of Virology, 1972 Synthesis of viral ribonucleic acid (RNA) polymerase, maturation protein, and coat protein in Escherichia coli infected with bacteriophage R17 occurs mainly on polysomes containing four or more ribosomes. The 30 S ribosomal subunits through trimer-size polysomes, which are associated with all
J L, Truden, R M, Franklin
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FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Analysis of Structural Changes in the Protein near the Phosphorylation Site
Biomolecules, 2023 Modification of the protein after synthesis (PTM) often affects protein function as supported by numerous studies. However, there is no consensus about the degree of structural protein changes after modification. For phosphorylation of serine, threonine,
Kirill S. Nikolsky +5 more
doaj +1 more source