Results 201 to 210 of about 39,378 (264)

Cyclic Olefin Copolymers as Versatile Materials for Advanced Engineering Applications

Advanced Functional Materials, Volume 36, Issue 47, 11 June 2026.
Cyclic olefin copolymers (COCs) are presented as highly versatile materials combining tunable synthesis, excellent optical properties, and mechanical robustness. Their potential spans microfluidics, bioengineering, and advanced electronics, while emerging self‐healing and sustainable solutions highlight future opportunities.
Giulia Fredi, Norma Mallegni, Andrea Dorigato, Mario Milazzo   +3 more
wiley   +1 more source

Outcomes in Locally Advanced Pancreatic Cancer After Induction Ablative Radiation Therapy and Resection. [PDF]

Ann Surg Oncol
Blair AB, Jolissaint JS, Foster D, Soares KC, Balachandran VP, Kingham TP, Drebin JA, D'Angelica MI, Jarnagin WR, Crane CH, Reyngold M, Wei AC.   +11 more
europepmc   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, Volume 13, Issue 35, 24 June 2026.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source

Single-Fraction SBRT for Locally Advanced Pancreatic Cancer Using Total Intravenous Anaesthesia and Optical Surface Guidance: Technique and Preliminary Results. [PDF]

Cancers (Basel)
Kaučić H, Karaman Ilić M, Kosmina D, Mišir Krpan A, Divošević S, Avdičević A, Feljan H, Lekić M, Schwarz K, Schwarz D.   +9 more
europepmc   +1 more source

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

Advanced Science, Volume 13, Issue 35, 24 June 2026.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård, Tatiana Bobrova, Amalie Leinebø, Thibault Leray, Shayamita Ghosh, Lorena García‐Hevia, Chiara Puccinelli, Lorenzo Riccio, Jacopo Sorani, Davide Bonifazi, Julien Caumartin, Emmanuel Donnadieu, Florence Gazeau, Roland Hischier, Else Marit Inderberg, Mónica L. Fanarraga, Maria Loustau, Bernd Nowack, Sébastien Wälchli, Cécilia Ménard‐Moyon   +19 more
wiley   +1 more source

Anatomical Classification and Staging Systems of Borderline Resectable and Locally Advanced Pancreatic Cancer-A Subgroup Analysis of the NORPACT-2 Trial. [PDF]

Ann Surg Oncol
Ghotbi J, Farnes I, Kleive D, Verbeke C, Epe AI, Fosby B, Line PD, Labori KJ.   +7 more
europepmc   +1 more source

Laparoscopic Delivery of a MnO2‐P‐ICG Patch for Photodynamic Therapy and NK Cell‐Driven Immunotherapy in Hepatocellular Carcinoma

Advanced Science, Volume 13, Issue 32, 9 June 2026.
This study proposes a flexible MnO2‐P‐ICG nanofiber patch for laparoscopic treatment of liver tumors. The patch alleviates tumor hypoxia and induces photodynamic therapy (PDT) triggered immunogenic cell death, thereby activating the cGAS‐STING pathway and, in synergy with pachymaran, promoting NK cell–mediated innate immunity. This synergistic strategy
Jie Lin, Haoqi Pan, Ke Wu, Junjie Nan, Jinyao Dai, Yushun Chang, Hao Shen, Qingxuan Ye, Haowen Lu, Yuxuan Shen, Boqiang Liu, Ming Wu, Jicheng Yu, Xiujun Cai, Dong Cen   +14 more
wiley   +1 more source

Pancreatectomy with Celiac Axis Resection and Reconstruction for Locally Advanced Pancreatic Cancer. [PDF]

Cancers (Basel)
Mizutani S, Taniai N, Sukegawa M, Haruna T, Furuki H, Takata H, Ueda J, Yoshioka M, Aimoto T, Sakamoto S, Suzuki K, Nakamura Y, Yoshida H.   +12 more
europepmc   +1 more source

Tumor‐Induced Splenic Remodeling: Mechanisms of Systemic Immunosuppression and Emerging Therapeutic Opportunities

Advanced Science, Volume 13, Issue 35, 24 June 2026.
ABSTRACT Despite the transformative impact of cancer immunotherapies such as immune checkpoint blockade, durable clinical responses remain limited. Increasing evidence indicates that antitumor immunity is governed not only by the tumor microenvironment, but also by systemic immune regulation mediated by peripheral immune organs. Among these, the spleen
Yuehua Liu, Xiaoqian Nie, Xiaofei Gao
wiley   +1 more source

Treatment of locally advanced pancreatic cancer with irreversible electroporation and intraoperative radiotherapy. [PDF]

Hepatobiliary Surg Nutr
Jiang L, Huang X, Hua X, Li Q, Zhang Y, Wang J, Li S.   +6 more
europepmc   +1 more source