Results 221 to 230 of about 39,378 (264)

Locally Advanced Pancreatic Cancer

Journal of Clinical Oncology, 2005
Of the 32,180 patients diagnosed with pancreatic carcinoma in the United States this year, approximately 40% will present with locally advanced disease. Radiotherapeutic approaches are often employed because these patients have unresectable tumors by virtue of local invasion into the retroperitoneal vessels in the absence of clinically detectable ...
Christopher G, Willett, Brian G, Czito, Johanna C, Bendell, David P, Ryan   +3 more
openaire   +2 more sources

Locally Advanced Pancreatic Cancer: A Review

Seminars in Oncology, 2007
It is anticipated that there will be 37,170 new cases of pancreatic cancer diagnosed in the United States this year, resulting in approximately 33,370 deaths from the disease. Approximately 40% of these patients will present with locally advanced, non-metastatic disease. Treatment regimens that incorporate conventional radiation therapy for local tumor
Suzanne, Russo, Jerome, Butler, Roger, Ove, A William, Blackstock   +3 more
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Therapeutic Advances in Localized Pancreatic Cancer

JAMA Surgery, 2016
It is estimated that pancreatic cancer (PC) will become the second leading cause of cancer-related death in the United States by 2030.Clinical and preclinical data support the understanding that PC metastases occur early in the pathogenesis of this disease, even before the primary tumor can be detected.
Susan, Tsai, Douglas B, Evans
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Management Options in Locally Advanced Pancreatic Cancer

Current Oncology Reports, 2014
Pancreatic ductal adenocarcinoma is a highly lethal cancer that is rarely curable at the time of presentation. Unfortunately, most patients are diagnosed with either metastatic or locally advanced disease, which is not amenable to surgery owing to the high likelihood of incomplete resection.
Omar Y, Mian, Ashwin N, Ram, Richard, Tuli, Joseph M, Herman   +3 more
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Current management of locally advanced pancreatic cancer

Nature Clinical Practice Gastroenterology & Hepatology, 2005
Almost 30% of patients with pancreatic cancer present with large, locally advanced tumors in the absence of distant metastases. Because surgical resection is frequently contraindicated by vascular invasion, locally advanced pancreatic cancer has a dismal prognosis with a 6-10-month median survival.
Vivek, Maheshwari, A James, Moser
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Locally advanced pancreatic cancer: An emerging entity

Current Problems in Cancer, 2018
Pancreatic adenocarcinoma (PDAC) remains a highly fatal disease that is increasing in incidence. PDAC can be classified according to resectability status with 3 nonmetastatic groups defined: resectable, borderline resectable, and locally advanced PDAC (LAPC).
Grainne M, O Kane, Jennifer J, Knox
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Ablative Therapies for Locally Advanced Pancreatic Cancer

Pancreas, 2018
Abstract The vast majority of patients who present with pancreatic adenocarcinoma have locally advanced or metastatic disease at the time of presentation without possibility of cure. Although in recent years there have been some new promising chemotherapy regimens that improve overall survival by a few months, the prognosis remains dismal ...
Rupen, Shah, Katherine T, Ostapoff, Boris, Kuvshinoff, Steven N, Hochwald   +3 more
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Gemcitabine–radiotherapy in patients with locally advanced pancreatic cancer

European Journal of Cancer, 2002
A feasibility study was performed to assess the toxicity and efficacy of a combination of gemcitabine-radiotherapy in patients with locally advanced pancreatic cancer (LAPC). 24 patients (15 females and 9 males) with measurable LAPC were included; the median age of the patients was 63 years (range 39-74 years). The performance status ranged from 0 to 2.
de Lange, S M, van Groeningen, C J, Meijer, O W M, Cuesta, M A, Langendijk, J A, van Riel, J M G H, Pinedo, H M, Peters, G J, Meijer, S, Slotman, B J, Giaccone, G   +10 more
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Locally Advanced/Unresectable Pancreatic Cancer

2017
When pancreatic cancer is not resectable or metastatic, it is classified as locally advanced pancreatic cancer. The majority of patients diagnosed with localized pancreatic cancer present with locally advanced disease. Currently, there is no consensus for optimal treatment of locally advanced pancreatic cancer.
Sweet Ping Ng, Michael E. Kantor, Sam Beddar, Eugene Koay, Joseph Herman, Cullen M. Taniguchi   +5 more
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Locally Advanced Pancreatic Cancer

Seminars in Oncology, 2012
William S, Auriemma, Adam C, Berger, Voichita, Bar-Ad, Patrick M, Boland, Steve J, Cohen, Caio Max S, Roche-Lima, Gloria J, Morris   +6 more
openaire   +2 more sources