Exploring Endovascular Photo-Activated Ablation (EPA) for Downstaging Locally Advanced Pancreatic Cancer: A Proof-of-Concept Study in the Normal Porcine Model. [PDF]
García Vázquez A +9 more
europepmc +1 more source
Targeting EZH2 in Cancer: From Molecular Mechanisms to Clinical Translation
The abnormal overexpression or gain‐of‐function mutations of EZH2 play a significant role in cancer occurrence and progression, highlighting the importance and potential of EZH2 as a cancer biomarker. Therefore, screening for effective and safe small‐molecule inhibitors, degraders, and natural compounds targeting EZH2 through preclinical cancer models ...
Xi Zhong +4 more
wiley +1 more source
Single-Fraction SBRT for Locally Advanced Pancreatic Cancer Using Total Intravenous Anaesthesia and Optical Surface Guidance: Technique and Preliminary Results. [PDF]
Kaučić H +9 more
europepmc +1 more source
ABSTRACT Purpose To quantitatively assess the bias in the intravoxel incoherent motions (IVIM)–derived pseudo‐diffusion volume fraction (f) caused by the differences in relaxation times between the tissue and fluid compartments, and to develop a two‐dimensional (b‐value‐TE) fitting approach for simultaneous T2 and IVIM parameter estimation along with ...
Julia Stabinska +4 more
wiley +1 more source
Anatomical Classification and Staging Systems of Borderline Resectable and Locally Advanced Pancreatic Cancer-A Subgroup Analysis of the NORPACT-2 Trial. [PDF]
Ghotbi J +7 more
europepmc +1 more source
ABSTRACT The high prevalence of gastrointestinal (GI) diseases and their significant impact on the quality of life require new therapeutic strategies. The development of novel therapeutic strategies should prioritize targeting the fundamental pathophysiological mechanisms underlying these diseases, including inflammation, cellular proliferation, and ...
Sayedeh Azimeh Hosseini +7 more
wiley +1 more source
Study protocol for a single-arm phase Ib/II trial of Ivonescimab combined with adapted guided stereotactic body radiotherapy and chemotherapy in patients with locally advanced pancreatic cancer. [PDF]
Tang Z +7 more
europepmc +1 more source
Abstract Background Animal cancer registry data are important for monitoring animal health, for prevention and research in veterinary medicine, and for comparative oncology. Since people and animals share the same environment and are exposed to many common risk factors, cancer patterns in animals may have a sentinel function for human health.
Claudio Trentin +10 more
wiley +1 more source
Pancreatectomy with Celiac Axis Resection and Reconstruction for Locally Advanced Pancreatic Cancer. [PDF]
Mizutani S +12 more
europepmc +1 more source
Phenol Neurolysis in Pain and Palliative Medicine
ABSTRACT Background Pain is a common symptom in palliative care and affects patients' quality of life considerably. Standard analgesics are sometimes insufficient and are associated with substantial side effects. Neurolysis, the targeted destruction of nerves using thermal or chemical agents, offers an additional option for managing localized pain in ...
Jeroen H. A. Creemers +6 more
wiley +1 more source

