Sono‐Mechanogenetics: Linking Ultrasound Physics With Cellular Mechanobiology
Sono‐mechanogenetics links ultrasound physics with cellular mechanotransduction to enable noninvasive control of engineered biological systems. Acoustic forces generate distinct deformation modes that activate intracellular signaling pathways, which can be coupled to synthetic gene circuits to regulate diverse cellular functions, including gene ...
Yunjia Qu +4 more
wiley +1 more source
Study protocol for a single-arm phase Ib/II trial of Ivonescimab combined with adapted guided stereotactic body radiotherapy and chemotherapy in patients with locally advanced pancreatic cancer. [PDF]
Tang Z +7 more
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This study elucidates the mechanisms of subcellular multidimensional collapse in exhausted T cells. By specifically targeting the nucleus, mitochondria, and endoplasmic reticulum, strategic interventions can effectively remodel the compromised organelle network. This integrated approach drives comprehensive T cell resuscitation, ultimately establishing
Mingxing Wang +9 more
wiley +1 more source
Online Adaptive Radiotherapy for an Elderly Patient With Locally Advanced Pancreatic Cancer. [PDF]
Jiang D, Peng J, Liu H, Wang X, Zhou F.
europepmc +1 more source
Indole 3-acetate and response to therapy in borderline resectable or locally advanced pancreatic cancer. [PDF]
Braadland PR +7 more
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Surgery and neoadjuvant therapy in locally advanced pancreatic cancer: an umbrella review of survival, resection outcomes, and cost-effectiveness. [PDF]
Zhao Y +4 more
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Pancreatoduodenectomy with vascular reconstruction versus chemotherapy alone in patients with locally advanced pancreatic cancer: a systematic review. [PDF]
Costa ACD +7 more
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Efficacy of irreversible electroporation combined with immunotherapy versus irreversible electroporation alone in locally advanced pancreatic cancer: a propensity score-matched retrospective study. [PDF]
Xi P +6 more
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Management of Locally Advanced Pancreatic Cancer
Surgical Clinics of North America, 2016The diagnosis for locally advanced pancreatic cancer is based on high-quality cross-sectional imaging, which shows tumor invasion into the celiac/superior mesenteric arteries and/or superior mesenteric/portal venous system that is not reconstructable.
exaly +3 more sources
Irreversible electroporation in locally advanced pancreatic cancer
Pirogov Russian Journal of Surgery, 2023Objective. To determine the feasibility of irreversible electroporation (IRE) for locally advanced pancreatic adenocarcinoma. Material and methods. Twenty-three patients underwent IRE after chemotherapy for locally advanced pancreatic cancer between 2015 and 2022. IRE was performed during laparotomy as a rule (n=22).
A.N. Polyakov +8 more
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