Common Hepatic Artery Resection and Reconstruction During Pancreaticoduodenectomy Following Chemotherapy for Locally-Advanced Pancreatic Cancer: A Case Report. [PDF]
Nakajima T +4 more
europepmc +1 more source
What's new? Adaptive immune responses are typically limited in pancreatic ductal adenocarcinoma, resulting in minimal efficacy of immune checkpoint inhibitors. Tumor Treating Fields (TTFields) therapy, which uses low‐intensity intermediate‐frequency electric fields to disrupt cancer cell processes, has been approved for certain cancers.
Tal Kan +21 more
wiley +1 more source
Surgical, Histopathological, and Quality of Life Outcomes Following Neoadjuvant Chemotherapy and Pancreatectomy for Borderline Resectable and Locally Advanced Pancreatic Cancer. [PDF]
Farnes I +8 more
europepmc +1 more source
Epigenetic Perspectives on Maternal Gut Microbiota's Impact on Embryonic and Fetal Development
This review summarizes how maternal health and nutrition shape gut microbiota via epigenetics to regulate embryonic development. It highlights microbiota‐embryo interactions, disruption by prenatal chemical exposures, and personalized nutrition for disease prevention, offering novel insights and therapeutic targets.
Shoulong Xu +6 more
wiley +1 more source
Inflammatory Biomarkers Predict Local Control and Survival After Escalated High-Dose SBRT in Borderline and Locally Advanced Pancreatic Cancer. [PDF]
Ferrera-Alayon L +5 more
europepmc +1 more source
What's new? Venous thromboembolism (VTE) is common in cancer patients, with direct oral anticoagulants, including rivaroxaban, recommended as first‐line therapy. However, oral anticoagulant use is limited due to the growing use of targeted therapy and concerns about drug‐drug interactions.
Esther M. Hollander +7 more
wiley +1 more source
Redirecting venous flow from the superior mesenteric vein to the inferior mesenteric vein in resections for locally advanced pancreatic cancer. [PDF]
Burgdorf SK +3 more
europepmc +1 more source
The Dual Role of Autophagy in Cancer: Mechanisms and Therapeutic Strategies
Autophagy is a conserved cellular process degrading dysfunctional organelles and protein aggregates to maintain cell homeostasis, and it exhibits context‐dependent duality in cancer. Autophagy functions as a critical tumor‐suppressive mechanism by preventing DNA damage and mutation during tumor initiation.
Xiang‐Zheng Gao +4 more
wiley +1 more source
First Spanish Experience with Stereotactic MR-Guided Adaptive Radiotherapy (SMART) in Borderline Resectable and Locally Advanced Pancreatic Cancer: A Prospective Study. [PDF]
Gonsalves D +29 more
europepmc +1 more source
Oxidative Stress in the Tumor Immune Microenvironment: Mechanisms and Therapeutic Perspectives
Oxidative stress is involved in several key processes in cancer, including redox regulation, DNA damage, post‐translational modifications, transcriptional regulation, epigenetic modifications, metabolic reprogramming, cell death, and immune modulation. These mechanisms collectively influence tumor progression, immune evasion, and therapeutic responses,
Zhen Wang +14 more
wiley +1 more source

