Results 271 to 280 of about 75,890 (310)

Locally advanced pancreatic cancer: An emerging entity

Current Problems in Cancer, 2018
Pancreatic adenocarcinoma (PDAC) remains a highly fatal disease that is increasing in incidence. PDAC can be classified according to resectability status with 3 nonmetastatic groups defined: resectable, borderline resectable, and locally advanced PDAC (LAPC).
Grainne M, O Kane, Jennifer J, Knox
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Management of Locally Advanced Pancreatic Cancer

Surgical Clinics of North America, 2016
The diagnosis for locally advanced pancreatic cancer is based on high-quality cross-sectional imaging, which shows tumor invasion into the celiac/superior mesenteric arteries and/or superior mesenteric/portal venous system that is not reconstructable.
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Ablative Therapies for Locally Advanced Pancreatic Cancer

Pancreas, 2018
Abstract The vast majority of patients who present with pancreatic adenocarcinoma have locally advanced or metastatic disease at the time of presentation without possibility of cure. Although in recent years there have been some new promising chemotherapy regimens that improve overall survival by a few months, the prognosis remains dismal ...
Rupen, Shah, Katherine T, Ostapoff, Boris, Kuvshinoff, Steven N, Hochwald   +3 more
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Locally Advanced/Unresectable Pancreatic Cancer

2017
When pancreatic cancer is not resectable or metastatic, it is classified as locally advanced pancreatic cancer. The majority of patients diagnosed with localized pancreatic cancer present with locally advanced disease. Currently, there is no consensus for optimal treatment of locally advanced pancreatic cancer.
Sweet Ping Ng, Michael E. Kantor, Sam Beddar, Eugene Koay, Joseph Herman, Cullen M. Taniguchi   +5 more
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Fast neutron irradiation for locally advanced pancreatic cancer

International Journal of Radiation Oncology*Biology*Physics, 1981
Abstract Nineteen patients with locally advanced pancreatic cancer and one patient with islet cell cancer were treated with 1700–1750 neutron rad alone or in combination with 5-flourouracil to exploit the theoretic advantages of higher linear energy of transfer, and lower oxygen enhancement ration of neutrons.
F P, Smith, P S, Schein, J S, Macdonald, P V, Woolley, R, Ornitz, C, Rogers   +5 more
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Surgical resection strategies for locally advanced pancreatic cancer

Langenbeck's Archives of Surgery, 2015
Despite all improvements in tumor diagnostics and treatment, pancreatic cancer is still the fourth leading cause of cancer-related death in the Western world. It is mostly diagnosed at a locally advanced or metastasized stage because of the lack of early symptoms.
Alexander, Gluth, Jens, Werner, Werner, Hartwig   +2 more
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Modified Appleby procedure for locally advanced pancreatic cancer

The American Journal of Surgery, 2018
Locally advanced pancreas cancer (LAPC) involving the celiac axis is typically considered unresectable and carries a poor prognosis. We present a case of a patient with LAPC who underwent a modified Appleby procedure for tumor clearance following neoadjuvant therapy.
Shanley, Deal, Derek, Nathan, Flavio G, Rocha   +2 more
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Does Neoadjuvant Chemoradiation Downstage Locally Advanced Pancreatic Cancer?

Journal of Gastrointestinal Surgery, 2002
Recent studies suggest that neoadjuvant chemoradiation can downstage locally advanced pancreatic tumors. There is limited evaluable data to support this approach. We review our experience with preoperative chemoradiation for surgically staged, locally advanced pancreatic cancer to determine whether patients are downstaged with multimodal therapy ...
Hong Jin, Kim, Karen, Czischke, Murray F, Brennan, Kevin C, Conlon   +3 more
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Prolonged Neoadjuvant Therapy for Locally Advanced Pancreatic Cancer

Digestive Surgery, 2017
<b><i>Purpose:</i></b> The purpose of this study was to investigate if prolonged neoadjuvant therapy, for locally advanced pancreatic cancer could be used to identify those patients who could benefit from resection surgery. <b><i>Methods:</i></b> Thirty-four patients with locally advanced pancreatic ...
Hidetoshi, Eguchi, Daisaku, Yamada, Yoshifumi, Iwagami, Kunihito, Gotoh, Koichi, Kawamoto, Hiroshi, Wada, Tadafumi, Asaoka, Takehiro, Noda, Yutaka, Takeda, Masahiro, Tanemura, Daisuke, Sakai, Taroh, Satoh, Toshihiro, Kudo, Fumiaki, Isohashi, Masaki, Mori, Yuichiro, Doki   +15 more
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Locally Advanced Pancreatic Cancer

Seminars in Oncology, 2012
William S, Auriemma, Adam C, Berger, Voichita, Bar-Ad, Patrick M, Boland, Steve J, Cohen, Caio Max S, Roche-Lima, Gloria J, Morris   +6 more
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