Using single‐cell RNA sequencing of lung samples and flow cytometry of peripheral blood, we identified a novel T cell subset with high metallothionein (MT) expression. These MT‐high T cells suppress CD8+ T cell cytotoxicity and are progressively depleted from healthy controls to chronic obstructive pulmonary disease (COPD) patients, positioning them as
Zengqing Liu +23 more
wiley +1 more source
Migrastatic therapy as a potential game-changer in adaptive cancer treatment. [PDF]
Schneider K +8 more
europepmc +1 more source
A Mussel‐Inspired Bioadhesive Patch to Selectively Kill Glioblastoma Cells
An innovative mussel‐inspired bioadhesive patch has been developed for post‐surgical glioblastoma treatment. The patch, which adheres strongly in biological environments, releases a localized treatment. This treatment, acting via reactive oxygen species, shows specific toxicity to glioblastoma cells.
Jose Bolaños‐Cardet +5 more
wiley +1 more source
A Cross-Sectional Survey on Musculoskeletal Pain Among Professional and Non-Professional Gamers in Saudi Arabia: Associations with Gaming Genre, Duration, and Ergonomic Factors. [PDF]
Alqabbani S +10 more
europepmc +1 more source
Electronic Structure Reorganization in MPS3 via d‐Shell‐Selective Alkali Metal Doping
Alkali metal doping of layered MPS3 antiferromagnets reveals d‐shell‐selective responses. While MnPS3 resists charge transfer due to its half‐filled 3d5 shell, FePS3 and NiPS3 behave similarly to CoPS3 by accommodating extra d‐electrons. Yet only CoPS3, with its least stable d‐shell, undergoes pronounced band restructuring and a semiconducting‐to ...
Jonah Elias Nitschke +12 more
wiley +1 more source
Quantification of heading in adult football: a systematic review and evidence synthesis. [PDF]
Alexander J +5 more
europepmc +1 more source
Heuristically Adaptive Diffusion‐Model Evolutionary Strategy
Building on the mathematical equivalence between diffusion models and evolutionary algorithms, researchers demonstrate unprecedented control over evolutionary optimization through conditional diffusion. By training diffusion models to associate parameters with specific traits, they can guide evolution toward solutions exhibiting desired behaviors ...
Benedikt Hartl +3 more
wiley +1 more source
Using a Multicomponent Implementation Strategy to Increase Adoption and Effectiveness of a Universal Mental Health Prevention Program in Australian Primary Schools: a Cluster Randomized Trial Using a Type-3 Hybrid Design. [PDF]
Baffsky R +10 more
europepmc +1 more source
Consensus Formation and Change are Enhanced by Neutrality
Neutral agents are shown to enhance both the formation and overturning of consensus in collective decision‐making. A general mathematical model and experiments with locusts and humans reveal that neutrality enables robust consensus via simple interactions and accelerates consensus change by reducing effective population size.
Andrei Sontag +3 more
wiley +1 more source

