Results 111 to 120 of about 8,859,889 (261)
Introduction to location-based mobile learning [PDF]
, 2010 [About the book] The report follows on from a 2-day workshop funded by the STELLAR Network of Excellence as part of their 2009 Alpine Rendez-Vous workshop series and is edited by Elizabeth Brown with a foreword from Mike Sharples.
Brown, Elizabeth
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Location, location: a polemic on photographs and institutional practices
Science Museum Group Journal, 2017 Professor Elizabeth Edwards
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Location, Location, Location [PDF]
ChemMedChem, 2011 Kozikowski, A., Botta, Maurizio
openaire +4 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Location, location, location : has electronic banking affected the importance of bank location? [PDF]
This article explores trends in consumer adoption of electronic banking products and services between 1995 and 2004. The article also discusses whether increasing use of electronic banking has impacted consumer sentiment regarding the importance of bank
Eric Robbins
core
New models for the location of controversial facilities: A bilevel programming approach [PDF]
, 2019 Motivated by recent real-life applications in Location Theory in which the location decisions generate controversy, we propose a novel bilevel location model in which, on the one hand, there is a leader that chooses among a number of fixed potential ...
Labbé, Martine +2 more
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source