Results 91 to 100 of about 72,586 (301)

Changes of grey matter volume in first-episode drug-naive adult major depressive disorder patients with different age-onset

NeuroImage: Clinical, 2016
Objective: Little is known about the pathological mechanism of early adult onset depression (EOD) and later adult onset depression (LOD). We seek to determine whether grey matter volume (GMV) change in EOD and LOD are different, which could also ...
Zonglin Shen, Yuqi Cheng, Shuran Yang, Nan Dai, Jing Ye, Xiaoyan Liu, Jin Lu, Na Li, Fang Liu, Yi Lu, Xuejin Sun, Xiufeng Xu   +11 more
doaj   +1 more source

Evolutionary associations between sand seatrout (Cynoscion arenarius) and silver seatrout (C. nothus) inferred from morphological characters, mitochondrial DNA, and microsatellite markers [PDF]

, 2009
The evolutionary associations between closely related fish species, both contemporary and historical, are frequently assessed by using molecular markers, such as microsatellites.
Anderson, Joel D., Karel, William J., McDonald, Dusty L., Sutton, Glen R.   +3 more
core  

A comparison of SNPs and microsatellites as linkage mapping markers: lessons from the zebra finch (Taeniopygia guttata) [PDF]

, 2010
Background: Genetic linkage maps are essential tools when searching for quantitative trait loci (QTL). To maximize genome coverage and provide an evenly spaced marker distribution a combination of different types of genetic marker are sometimes used.
Ball, A.D., Birkhead, T.R., Burke, T., Dawson, D.A., Slate, J., Stapley, J.   +5 more
core   +3 more sources

Unlocking the Potential of MXene‐Based Electrochemical Biosensors: A Review of Biofunctionalization Strategies and Biosensing Principles

Advanced Materials Technologies, EarlyView.
ABSTRACT Electrochemical biosensors enable the accurate and timely detection of clinical biomarkers, improving healthcare and precision medicine. MXene nanosheets, a class of 2D transition metal carbides, nitrides, and carbonitrides, are promising materials for developing next‐generation electrochemical biosensors due to their unique physicochemical ...
Muhsin Ali, Sharat Chandra Barman, Isobel Steer, Aya H. Alshareef, Dana Alsulaiman   +4 more
wiley   +1 more source

Genetic Dissection of a QTL Affecting Bone Geometry. [PDF]

, 2017
Parameters of bone geometry such as width, length, and cross-sectional area are major determinants of bone strength. Although these traits are highly heritable, few genes influencing bone geometry have been identified.
Farber, Charles R, Medrano, Juan F, Sabik, Olivia L   +2 more
core   +2 more sources

Graphene‐Interfaced Stretchable Sweat Patch for Multiplexed Electrochemical Monitoring of IL‐6, Glucose, and Calcium Ions

Advanced Materials Technologies, EarlyView.
Flexible sweat sensor patch integrating graphene‑interfaced gold microelectrodes functionalized with bio‑receptors and ion‑selective membrane, coupled with a capillary‑driven microfluidic layer and portable potentiostat electronics for multiplexed monitoring of inflammatory, metabolic, and electrolyte biomarkers in microliter sweat volumes.
Roomia Memon, Ali Tufani, Süleyman Çelik, Javed H. Niazi, Anjum Qureshi   +4 more
wiley   +1 more source

Flexible and High‐Performance Perovskite‐Polymer Composites for Dual X‐Ray and Proton Direct Detection

Advanced Optical Materials, EarlyView.
A polymer–perovskite composite obtained by mechanochemical synthesis enables thick, tunable active layers for efficient absorption of highly penetrating ionizing radiation. Vertical‐electrode detectors achieve low X‐ray detection limits and high sensitivity direct 5 MeV proton sensing.
Camilla Bordoni, Bas A. H. Huisman, Joost W. C. Reinders, Ilaria Fratelli, Massimo Chiari, Laura Basiricò, Henk J. Bolink, Andrea Ciavatti, Michele Sessolo, Beatrice Fraboni   +9 more
wiley   +1 more source

Genetic variation in hippocampal microRNA expression differences in C57BL/6 J X DBA/2 J (BXD) recombinant inbred mouse strains [PDF]

, 2012
BACKGROUND: miRNAs are short single-stranded non-coding RNAs involved in post-transcriptional gene regulation that play a major role in normal biological functions and diseases. Little is currently known about how expression of miRNAs is regulated.
Chesler, E., Fernandes, C., Grimm, C., Lehrach, H., Liu, L., Nietfeld, W., Parsons, M., Paya-Cano, J., Philip, V., Schalkwyk, L.   +9 more
core   +3 more sources

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source

Identify changes of brain regional homogeneity in early and later adult onset patients with first-episode depression using resting-state fMRI.

PLoS ONE, 2017
ObjectivePrevious work exhibited different brain grey matter volume (GMV) changes between patients with early adult onset depression (EOD, age 18-29) and later adult onset depression (LOD, age 30-44) by using 30-year-old as the cut-off age.
Zonglin Shen, Linling Jiang, Shuran Yang, Jing Ye, Nan Dai, Xiaoyan Liu, Na Li, Jin Lu, Fang Liu, Yi Lu, Xuejin Sun, Yuqi Cheng, Xiufeng Xu   +12 more
doaj   +1 more source