Results 101 to 110 of about 1,870,567 (303)

An Engineered Supramolecular Pathway for Enhanced Electrochemiluminescence

open access: yesAdvanced Science, EarlyView.
A supramolecular electrochemiluminescent (ECL) system is presented in which cucurbit[7]uril (CB7) is covalently linked to [Ru(bpy)3]2+, forming a recognition‐responsive emitter. Host‒guest preorganization of tri‐n‐propylamine enables intramolecular ECL, boosting intensity by 162% compared to the standard system.
Maria Vittoria Balli   +7 more
wiley   +1 more source

LOD score

open access: yes
Citation: 'LOD score' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.10899 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Profiles of the LOD score for SDL declaration throughout the male and female maps.

open access: yes, 2015
2a. The male map; 2b. The female map. Note: Y-axis shows the LOD score, and X-axis displays the accumulated genetic length in order of the linkage group numbers. The Rome digital on the top of the figure are the linkage group identities.
Jing Hou (18672)   +4 more
core   +1 more source

CRISPR‐Scan: Cas13a Mismatch Tolerance Enabled Ultra‐Multiplexed Detection of Same‐Site Indels in Acute Myeloid Leukemia

open access: yesAdvanced Science, EarlyView.
Accurately detecting diverse same‐locus insertions or deletions (indels) remains challenging. This study reveals the mismatch‐tolerance profile of LwaCas13a and establishes CRISPR‐Scan, which uses a single crRNA to detect multiple same‐locus indels. The one‐pot assay detects nucleophosmin 1 (NPM1) mutant allele frequencies down to 0.01%, agrees with ...
Linlin Bai   +13 more
wiley   +1 more source

Comprehensive Performance Verification of the Mindray MN2880 System in Detecting Respiratory Virus Nucleic Acids. [PDF]

open access: yesJ Clin Lab Anal
This study verified the analytical performance of the fully automated Mindray MN2880 system for the simultaneous detection of SARS‐CoV‐2, influenza A/B viruses, and RSV in 2852 oropharyngeal swab specimens, following CNAS‐GL039:2019, CNAS‐GL037:2019, and ISO 15189:2022 guidelines.
Chen J, Zeng L, Huang H, Chen P.
europepmc   +2 more sources

Whole genome two-point LOD scores obtained from stratified analysis.

open access: yes, 2013
LOD score thresholds of 2 and 3 are indicated by the blue and red lines, respectively. HLOD scores for CTD-negative (A) and CTD-positive family subsets (B), and LOD scores under an exponential model for CTD-negative (C) and CTD-positive family subsets (D)
Kaitlyn Dunlap (404508)   +10 more
core   +1 more source

Scaffold RNA Reengineering for a Leakage‐Suppressed CRISPR/Cas12a Cascade System Toward Precise Nucleic Acid Diagnostics

open access: yesAdvanced Science, EarlyView.
Schematic illustration of the CALCas system, in which a conformational switch in the 3' terminal DNA extension of scaffold RNA (3'D‐SR) drives cascade‐activatable Cas12a cleavage while suppressing leakage. ABSTRACT Amplification‐free CRISPR detection has attracted significant attention for its capacity to circumvent the intricacies of nucleic acid ...
Xingrong Li   +11 more
wiley   +1 more source

Calibration of LOD scoring in a high mortality population

open access: yesBritish Journal of Anaesthesia, 2000
The population of the North West suffers higher comorbidity rates than that of England as a whole. Standardized mortality ratios for ischaemic heart disease (1.2), cerebrovascular disease (1.16) and chronic obstructive airways disease (1.4) are all significantly higher than the national average.1 Nine intensive care units based in the North West ...
D.A. Sperry, J. Eddleston
openaire   +1 more source

Lod score analysis for genome wide scan spanning the susceptibility region on Chromosome 6 for AS disease, IBP and HLA-B27 clinical traits.

open access: yes, 2016
Lod score analysis for genome wide scan spanning the susceptibility region on Chromosome 6 for AS disease, IBP and HLA-B27 clinical traits.
Qiujing Wei (534852)   +12 more
core   +1 more source

Sub‐Second Ratiometric Fluorescence Imaging of Histamine Dynamics in Living Cells via a Supramolecular Probe

open access: yesAdvanced Science, EarlyView.
A tailored tripartite supramolecular ratiometric probe, engineered by modulating the fluorogenic guest's cationic locus, enables ultrafast histamine monitoring in living cells. Utilizing a competitive displacement mechanism, this system achieves a sub‐second response time with high selectivity.
Chenming Chan   +4 more
wiley   +1 more source

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