Results 121 to 130 of about 33,686 (303)

SERS Facemask for Rapid and Portable Sensing Mycobacterium Tuberculosis Antigens for TB Screening

Advanced Science, EarlyView.
Our study introduced an Au─Ag embedded covalent organic framework (U@COF) ‐mediated facemask for sensing TB antigen ESAT‐6/CFP‐10 complex in clinical droplet samples toward TB screening. Practical analysis of clinical samples demonstrated the availability of our facemask, which is capable of identifying the TB subjects (N = 17) from healthy candidates (
Lingzhi Chen, Jiaqi Yu, Jing Xu, Lingqi Chen, Ninghao Zhang, Wenrui Li, Runmin Zeng, Xiaomin Luo, Yiqun Chang, Jiayin Lai, Wenshi Huang, Xiaochen Liang, Ting Zhao, Shanze Chen, Huaihong Cai, Yanguang Cong, Pinghua Sun, Jiang Pi, Xueqin Huang, Haibo Zhou, Junxia Zheng   +20 more
wiley   +1 more source

eQTLs overlapping the 1.5 LOD drop region of the PR QTL.

, 2013
Transcripts with a significant linkage overlapping the 1.5 LOD drop region of the PR QTL are listed with their genomic location (build NCBIM37), specific LOD score, marker with the highest LOD score, Spearmans correlation to PR (Rho and uncorrected p ...
Elisabeth M. Lodder (295429), Douglas A. Marchuk (242744), Annalisa Milano (295433), Geoffrey S. Pitt (107104), Connie R. Bezzina (215605), Michael W. T. Tanck (295438), Carol Ann Remme (295436), Perry D. Moerland (201141), Hao Tang (44155), Brendon P. Scicluna (295431), Albert Y. Sun (107100)   +10 more
core   +1 more source

Optimization of B Cell Responses in Human Immune System Mice Through Organoid Based Screening

Advanced Science, EarlyView.
Human immune system (HIS) mice show limited B cell responses to immunization. Using HIS mouse spleen organoids, this study identifies cytokine combinations and innate immune signals that drive human B cell expansion, differentiation, and class‐switch. Applying these signals in vivo through temporal separation enables antigen‐specific IgG responses and ...
Haiqiao Sun, He Li, Xu Zhu, Zijian Zhang, Deshan Ren, Shuai Ding, Yan Li   +6 more
wiley   +1 more source

Graphical representation of parametric linkage results suggestive of linkage (LOD score >2.5) in the multiplex AAD families, assuming a rare dominant model.

, 2015
Graphical representation of parametric linkage results in the multiplex AAD families, assuming a rare dominant model. The LOD/HLOD score is on the y axis and the cM position is on the x axis.
Eystein S. Husebye (749607), Simon H. S. Pearce (532791), Katie MacArthur (749603), Martina M. Erichsen (749605), Anette Bøe Wolff (749602), Bijay Vaidya (280337), Rebecca Darlay (749606), Heather J. Cordell (173189), Anna L. Mitchell (532768), Jolanta U. Weaver (749604)   +9 more
core   +1 more source

Toward Prostate Cancer Early Warning with a Self‐Powered Wearable Biosensing Platform Integrated with Machine Learning

Advanced Science, EarlyView.
ABSTRACT Current prostate cancer detection methods remain limited in non‐invasiveness and specificity, prompting interest in urinary biomarkers such as sarcosine. Here, we report a urine‐powered wearable platform for non‐invasive sarcosine detection as a proof‐of‐concept for decentralized early warning.
Jing Xu, Hanxiao Chen, Qichen Yuan, Liucun Yin, Yifang Tao, Hong Wang, Yuquan Xue, Delai Fu, Huan Pang, Tie Chong, Li Xue   +10 more
wiley   +1 more source

Heat map of LOD scores.

, 2013
A graphical representation (heat map) of the LOD score data (cut-off ≥2.0) was generated to visually demonstrate the computed linkage scores for each subgroup in a hierarchy. The heat map compares LOD score patterns for the 16 subgroups.
Valerie W. Hu (223231), Zohreh Talebizadeh (426958), Dan E. Arking (143354)   +2 more
core   +1 more source

Biolipid Film‐Fused Electrochemiluminescence for Multipurpose In Situ Bioassays

Advanced Science, EarlyView.
An ECL‐emissive, membrane‐interactive scaffold was fabricated, and facilely fused with natural and non‐native phospholipids into multifactorial mimicries of cytomembranes and vesicles for in vitro representative membrane‐process probing. Such a biointerface‐based, state‐sensitive ECL paradigm not only pinpointed proximal phenomena, including channeling
Jialiang Chen, Bin Li, Yingying Wang, Fulin Zhu, Wenxuan Yang, Xuanyu Fu, Tiantian Man, Qiuyue Wu, Kewei Ren, Shengyuan Deng   +9 more
wiley   +1 more source

LOD-Plot showing genome wide linkage analysis in all three families.

, 2015
19 linkage regions with a maximum LOD-score of 1.62 were identified, which are illustrated by multipoint LOD scores above background.
Steffen Uebe (390051), André Rüffer (740629), Sven Dittrich (740628), Julia Moosmann (740627), Arif B. Ekici (146432), Okan Toka (740630)   +5 more
core   +1 more source

Spontaneous Non‐Catalyzed Molecular Reactions and Interactions in the Human Body: Biomedical Implications

Advanced Science, EarlyView.
ABSTRACT The human body functions as a natural reactor for a vast network of chemical and biological reactions and physical interactions among small molecules, proteins, cells, and numerous other components. These reactions/interactions are essential for maintaining normal physiological functions.
Yuhao Cai, Chao Zhao
wiley   +1 more source

Interaction LOD scores for phenotypes significant at the genome-wide level (P<0.05).

, 2013
Two-way epistatic interactions for S. lycopersicum/S. pimpinellifolium RIL population across all 12 chromosomes.aLod.full is the LOD score of the full model with two loci and their interaction compared to the null model with no QTL.bLod.fv1 is the LOD ...
Henk W. M. Hilhorst (192194), Rashid H. Kazmi (309372), Leo A. J. Willems (309373), Adriaan W. van Heusden (309374), Wilco Ligterink (192192), Noorullah Khan (309371)   +5 more
core   +1 more source