Results 81 to 90 of about 33,686 (303)

Comparison of multipoint linkage analyses for quantitative traits in the CEPH data: parametric LOD scores, variance components LOD scores, and Bayes factors [PDF]

BMC Proceedings, 2007
Abstract We performed multipoint linkage analyses with multiple programs and models for several gene expression traits in the Centre d'Etude du Polymorphisme Humain families. All analyses provided consistent results for both peak location and shape. Variance-components (VC) analysis gave wider peaks and Bayes factors gave fewer peaks.
Sung, Yun, Di, Yanming, Fu, Audrey Q, Rothstein, Joseph H, Sieh, Weiva, Tong, Liping, Thompson, Elizabeth A, Wijsman, Ellen M   +7 more
openaire   +2 more sources

Whole genome scan LOD score plot for plasma total cholesterol in the F2 mice showing significance thresholds.

, 2015
Whole genome scan LOD score plot for plasma total cholesterol in the F2 mice showing significance thresholds.
Lars Bo Nielsen (316976), Jeong Shim (721565), Jacob F. Bentzon (721567), Caroline Östergren (721564), Jens Vinther Larsen (721566)   +4 more
core   +1 more source

End‐to‐End Sensing Systems for Breast Cancer: From Wearables for Early Detection to Lab‐Based Diagnosis Chips

Advanced Materials Technologies, EarlyView.
This review explores advances in wearable and lab‐on‐chip technologies for breast cancer detection. Covering tactile, thermal, ultrasound, microwave, electrical impedance tomography, electrochemical, microelectromechanical, and optical systems, it highlights innovations in flexible electronics, nanomaterials, and machine learning.
Neshika Wijewardhane, Lyn I. Jones, Richard M. Martin, Helen Winter, Faezeh Arab Hassani   +4 more
wiley   +1 more source

The effect of ascertainment on penetrance estimates for rare variants: Implications for establishing pathogenicity and for genetic counselling.

PLoS ONE, 2023
Next-generation sequencing has led to an explosion of genetic findings for many rare diseases. However, most of the variants identified are very rare and were also identified in small pedigrees, which creates challenges in terms of penetrance estimation ...
Andrew D Paterson, Sang-Cheol Seok, Veronica J Vieland   +2 more
doaj   +1 more source

Lod score with non-parameter linkage analysis on all 22 chromosomes for AS disease for Illumina SNP markers.

, 2016
Lod score with non-parameter linkage analysis on all 22 chromosomes for AS disease for Illumina SNP markers.
Qiujing Wei (534852), Xinwei Wang (352488), Zhiming Lin (3402026), Jieruo Gu (534854), Zetao Liao (740110), Zishi Guo (3545231), Yunfeng Pan (319280), Shuangyan Cao (534853), Yuqiong Wu (751484), Ju Rong (740108), Yanli Zhang (309699), Ou Jin (3545237), Manlong Xu (3545234)   +12 more
core   +1 more source

Transducers Across Scales and Frequencies: A System‐Level Framework for Multiphysics Integration and Co‐Design

Advanced Materials Technologies, EarlyView.
Transducers convert physical signals into electrical and optical representations, yet each mechanism is bounded by intrinsic trade‐offs across bandwidth, sensitivity, speed, and energy. This review maps transduction mechanisms across physical scale and frequency, showing how heterogeneous integration and multiphysics co‐design transform isolated ...
Aolei Xu, Mengyao Xiao, Zhouli Sui, Yinpeng Wang, Daoye Zheng, Yuxin Liu, Luwei Wang, Huajun Liu, Chengkuo Lee   +8 more
wiley   +1 more source

Changes of grey matter volume in first-episode drug-naive adult major depressive disorder patients with different age-onset

NeuroImage: Clinical, 2016
Objective: Little is known about the pathological mechanism of early adult onset depression (EOD) and later adult onset depression (LOD). We seek to determine whether grey matter volume (GMV) change in EOD and LOD are different, which could also ...
Zonglin Shen, Yuqi Cheng, Shuran Yang, Nan Dai, Jing Ye, Xiaoyan Liu, Jin Lu, Na Li, Fang Liu, Yi Lu, Xuejin Sun, Xiufeng Xu   +11 more
doaj   +1 more source

Two-point and multipoint LOD scores obtained from stratified analysis.

, 2013
Only chromosomes with a maximum multipoint LOD score >2 are shown. LOD score thresholds of 2 and 3 are indicated by the blue and red lines, respectively.
Kaitlyn Dunlap (404508), Karen Soldano (167738), Herbert Fuchs (404512), David Enterline (404511), Simon G. Gregory (268051), Edgar Asiimwe (404510), Gerald Grant (104491), Heidi Cope (404509), Christina A. Markunas (404507), Jeffrey Stajich (119693), Allison E. Ashley-Koch (119700)   +10 more
core   +1 more source

Multimodal Haptic Perception Through Synergistic Nanocomposite Sensor Arrays

Advanced Materials Technologies, EarlyView.
Multi‐modal fingertip haptics are advanced through a bioinspired &vertical‐via' electronic skin architecture. A confined PDMS/MWCNT/NiNP nanocomposite, sitting at the percolation threshold, enables tactile, thermal, and magnetic sensing. A unique via‐density gradient and dedicated &Un‐Touch' reference nodes provide robust spatial resolution and signal ...
Amos Bardea, Fernando Patolsky
wiley   +1 more source

Graphene‐Interfaced Stretchable Sweat Patch for Multiplexed Electrochemical Monitoring of IL‐6, Glucose, and Calcium Ions

Advanced Materials Technologies, EarlyView.
Flexible sweat sensor patch integrating graphene‑interfaced gold microelectrodes functionalized with bio‑receptors and ion‑selective membrane, coupled with a capillary‑driven microfluidic layer and portable potentiostat electronics for multiplexed monitoring of inflammatory, metabolic, and electrolyte biomarkers in microliter sweat volumes.
Roomia Memon, Ali Tufani, Süleyman Çelik, Javed H. Niazi, Anjum Qureshi   +4 more
wiley   +1 more source