Results 61 to 70 of about 72,586 (301)

Handling linkage disequilibrium in qualitative trait linkage analysis using dense SNPs: a two-step strategy

BMC Genetics, 2009
Background In affected sibling pair linkage analysis, the presence of linkage disequilibrium (LD) has been shown to lead to overestimation of the number of alleles shared identity-by-descent (IBD) among sibling pairs when parents are ungenotyped.
Dupuis Josée, Cho Kelly
doaj   +1 more source

Comparison of empirical strategies to maximize GENEHUNTER lod scores [PDF]

Genetic Epidemiology, 1999
AbstractWe compare four strategies for finding the settings of genetic parameters that maximize the lod scores reported in GENEHUNTER 1.2. The four strategies are iterated complete factorial designs, iterated orthogonal Latin hypercubes, evolutionary operation, and numerical optimization.
C H, Chen, S J, Finch, N R, Mendell, D, Gordon   +3 more
openaire   +2 more sources

Meta-analysis of four new genome scans for lipid parameters and analysis of positional candidates in positive linkage regions [PDF]

, 2005
Lipid levels in plasma strongly influence the risk for coronary heart disease. To localise and subsequently identify genes affecting lipid levels, we performed four genome-wide linkage scans followed by combined linkage/association analysis. Genome-scans
A Hamsten, AR Tall, Bastiaan T Heijmans, C Jurinke, CJ Etzel, DA Tregouet, Daniëlle Posthuma, DC Crawford, DC Rao, DL Rainwater, Dorret I Boomsma, E Lander, G Imperatore, G. Assmann, GP Vogler, GR Abecasis, GR Abecasis, GR Abecasis, H Coon, H Coon, H Knoblauch, HC van Houwelingen, Hein Putter, Henk Jan van der Wijk, J Blangero, J Lebrec, JC Cohen, JK Pritchard, JM Peacock, John B Whitfield, L Almasy, L Ose, L Peltonen, M Beekman, M Beekman, M Beekman, M Beekman, M Falchi, Marian Beekman, N Tahri-Daizadeh, Nancy L Pedersen, NE Morton, Nicholas G Martin, Nico Lakenberg, NJ Risch, P Eline Slagboom, P Libby, P Pajukanta, PC Sham, R DerSimonian, SM Fullerton, TI Pollin, Y Bossé   +52 more
core   +2 more sources

Design Strategies and Emerging Applications of High‐Performance Flexible Piezoresistive Pressure Sensors

Advanced Functional Materials, EarlyView.
Flexible piezoresistive pressure sensors underpin wearable and soft electronics. This review links sensing physics, including contact resistance modulation, quantum tunneling and percolation, to unified materials/structure design. We highlight composite and graded architectures, interfacial/porous engineering, and microstructured 3D conductive networks
Feng Luo, Artur Ciesielski, Paolo Samorì   +2 more
wiley   +1 more source

C-Reactive Protein as an Indicator for Antidepressant Response in Late-Onset Depression: A prospective Study [PDF]

Perspectives In Medical Research
Introduction: Late-onset depression (LOD), often linked to immune dysfunction and vascular factors, presents distinct treatment challenges compared to early-onset depression. Predicting treatment outcomes remains difficult.
Dheerendra Kumar​ Mishra, Umesh Pratap Singh, Ujwal Sardesai   +2 more
doaj   +1 more source

Cardiac troponin I and T for ruling out coronary artery disease in suspected chronic coronary syndrome

Scientific Reports, 2022
To compare the performance of high-sensitivity cardiac troponin I and T (hs-cTnI; hs-cTnT) in diagnosing obstructive coronary artery disease (CAD50) in patients with suspected chronic coronary syndrome (CCS).
Sjur H. Tveit, Peder L. Myhre, Tove Aminda Hanssen, Signe Helene Forsdahl, Amjid Iqbal, Torbjørn Omland, Henrik Schirmer   +6 more
doaj   +1 more source

NELLIE: Never-Ending Linking for Linked Open Data

IEEE Access, 2023
Knowledge graphs (KGs) that follow the Linked Data principles are created daily. However, there are no holistic models for the Linked Open Data (LOD). Building these models(i.e., engineering a pipeline system) is still a big challenge in order to make ...
Abdullah Fathi Ahmed, Mohamed Ahmed Sherif, Axel-Cyrille Ngonga Ngomo   +2 more
doaj   +1 more source

Fluorescent Nanosensor for Indole‐3‐Propionic Acid Detection in Gut Health Monitoring

Advanced Healthcare Materials, EarlyView.
This work introduces a fluorescent nanosensor system with two optical modalities for detection of indole‐3‐propionic acid (IPA) gut metabolite: (1) blue‐emitting cationic conjugated polyelectrolyte (CP3) and (2) near‐infrared (NIR)‐emitting CP3‐wrapped single‐walled carbon nanotube (SWNT).
Mervin Chun‐Yi Ang, Jonathan Wei Jie Lee, Sayyid Mohaideen, Gabriel Sánchez‐Velázquez, Song Wang, Yangyang Han, Liu Lin, Germaine Yong, Raju Cheerlavancha, Duc Thinh Khong, Jianhong Ching, Sharon Hong Yu Han, Jun Yu Yeo, Lian Xu, Gajendra Pratap Singh, Michael S. Strano   +15 more
wiley   +1 more source

Genome-wide Analysis of Host-Plasmodium yoelii Interactions Reveals Regulators of the Type I Interferon Response

Cell Reports, 2015
Invading pathogens trigger specific host responses, an understanding of which might identify genes that function in pathogen recognition and elimination.
Jian Wu, Baowei Cai, Wenxiang Sun, Ruili Huang, Xueqiao Liu, Meng Lin, Sittiporn Pattaradilokrat, Scott Martin, Yanwei Qi, Sethu C. Nair, Silvia Bolland, Jeffrey I. Cohen, Christopher P. Austin, Carole A. Long, Timothy G. Myers, Rong-Fu Wang, Xin-zhuan Su   +16 more
doaj   +1 more source

A new perspective on sexual mixing among men who have sex with men by body image. [PDF]

PLoS ONE, 2014
"Casual sex" is seldom as non-selective and random as it may sound. During each sexual encounter, people consciously and unconsciously seek their casual sex partners according to different attributes. Influential to a sexual network, research focusing on
Ka-Kit Leung, Horas T H Wong, Claire M Naftalin, Shui Shan Lee   +3 more
doaj   +1 more source