Results 31 to 40 of about 33,686 (303)
Background In the last years GWA studies have successfully identified common SNPs associated with complex diseases. However, most of the variants found this way account for only a small portion of the trait variance.
Flaquer Antònia, Strauch Konstantin
doaj +1 more source
Interval Mapping Using Nonparametric Accelerated Failure Time Cure Model [PDF]
Many important problems in evolutionary biology begin with observations of phenotypic variation. Suppose time to an event-data are used to map quantitative trait loci (QTL) and underlying population is a mixture of susceptible and non-susceptible ...
Devrim Bilgili, Nader Ebrahimi
doaj +1 more source
Lod score values varying the D' value between marker 4 and disease locus A.
Unstratified lod score is represented by solid line and stratified lod score by dashed line. Horizontal dotted line identifies the threshold for significant evidence of linkage.
David A. Greenberg (319010) +1 more
core +1 more source
Soil salinity is one of the major environmental constraints that limits crop yield and nearly 7% of the total area worldwide is affected by salinity. Salinity-induced oxidative stress causes membrane damage during germination and seedling growth.
Rekha Patel +4 more
doaj +1 more source
Electrocardiogram (ECG) measurements play a key role in the diagnosis and prediction of cardiac arrhythmias and sudden cardiac death. ECG parameters, such as the PR, QRS, and QT intervals, are known to be heritable and genome-wide association studies ...
Claudia Tamar Silva +23 more
doaj +1 more source
Variation in LOD score distribution by position on Chr 1.
Distribution of 95th percentile LOD scores by marker for 10,000 GRAIP permutations of coat color and body weight QTL mapping in the AIL population. Note that the maximum and minimum values of the 95th percentile on this chromosome alone are separated by ...
Jeremy L. Peirce (80213) +7 more
core +1 more source
A genome-wide linkage study was performed to identify chromosomal regions harboring genes influencing lipid and lipoprotein levels. Linkage analyses were conducted for four quantitative lipoprotein/lipid traits, i.e., total cholesterol, triglyceride, HDL-
Y. Bossé +7 more
doaj +1 more source
LOD score distributions from CERVUS analyses of parentage in three-toed woodpeckers.
(a) LOD score for the candidate males that have been unequivocally assigned as fathers (▪) and for candidate males that were the second most likely candidate excluded (□) (N = 80); (b) LOD score for the candidate females that have been unequivocally ...
Markus Piha (369243) +4 more
core +1 more source
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Prognostic values of SOFA score, qSOFA score, and LODS score for patients with sepsis
Sepsis continues to carry a high rate of mortality, which makes effective and simple evaluation methods for predicting the prognosis of septic patients especially important. In this study, we retrospectively analyzed the relationships between three scoring systems including Sequential Organ Failure Assessment (SOFA) score, Quick SOFA (qSOFA) score, and
Yonglin, Li +6 more
openaire +2 more sources

