Results 51 to 60 of about 4,810,089 (329)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
EntropyA new methodology is introduced to solve classical Boolean problems as Hamiltonians, using the quantum approximate optimization algorithm (QAOA). This methodology is termed the “Boolean-Hamiltonians Transform for QAOA” (BHT-QAOA). Because a great deal of
Ali Al-Bayaty, Marek Perkowski
doaj +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
MILO : a microarchitecture and logic optimizer [PDF]
, 1988 In this report we discuss strengths and weaknesses of logic synthesis systems and describe a system for microarchitectural and logic optimization. Our system uses a set of algorithms for synthesizing SSI/MSI macros from parameterized microarchitecture ...
Gajski, Daniel, Zanden, Nels Vander
core
A recursive paradigm to solve Boolean relations [PDF]
, 2008 A Boolean relation can specify some types of flexibility of a combinational circuit that cannot be expressed with don't cares. Several problems in logic synthesis, such as Boolean decomposition or multilevel minimization, can be modeled with Boolean ...
Bañeres Besora, David +2 more
core +3 more sources
High-Performance Placement for VLSI Logic Synthesis
AlgorithmsLogic synthesis is a critical stage in the VLSI design flow. Logic synthesis methods without considering physical information would result in inferior solutions with timing violations and fail to meet high-performance design requirements.
Zhifeng Lin +3 more
doaj +1 more source
An Improved iMemComp OR Gate and its Applications in Logic Circuits
IEEE Journal of the Electron Devices Society, 2020 The iMemComp (Intelligent memristive computing) gates are a family of logic gates based on the RRAM (Resistive Random Access Memory) devices. It has potential advantage for the design of high-performance logic circuits, because the iMemComp NAND, AND ...
Feng Wei, Xiaole Cui, Xiaoxin Cui
doaj +1 more source
, 2016 We study the reactive synthesis problem (RS) for specifications given in Metric Interval Temporal Logic (MITL). RS is known to be undecidable in a very general setting, but on infinite words only; and only the very restrictive BRRS subcase is known to be
A Bohy +14 more
core +3 more sources
Incremental Control Synthesis in Probabilistic Environments with Temporal Logic Constraints [PDF]
, 2012 In this paper, we present a method for optimal control synthesis of a plant that interacts with a set of agents in a graph-like environment. The control specification is given as a temporal logic statement about some properties that hold at the vertices ...
Belta, Calin +2 more
core +2 more sources
Planar Solid‐State Nanopores Toward Scalable Nanofluidic Integration Based on CMOS Technology
Advanced Engineering Materials, EarlyView.We present a scalable silicon‐based fabrication strategy for planar solid‐state nanopores to enable their integration with complex nanofluidic systems. Prototype devices demonstrate normal voltage‐current characteristics, good noise performance, and appreciable streaming currents. Our CMOS‐compatible fabrication process offers precise geometric control
Ngan Hoang Pham +7 more
wiley +1 more source