Results 1 to 10 of about 3,246,734 (361)

Alteration of the gut microbiome and correlated metabolism in a rat model of long-term depression [PDF]

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
ObjectiveThis study aims to investigate the composition and function of the gut microbiome in long-term depression using an 8-week chronic unpredictable mild stress (CUMS) rat model.Materials and methodsAnimals were sacrificed after either 4 weeks or 8 ...
Yubo Li   +12 more
doaj   +2 more sources

Long-term potentiation and long-term depression: a clinical perspective [PDF]

open access: yesClinics, 2011
Long-term potentiation and long-term depression are enduring changes in synaptic strength, induced by specific patterns of synaptic activity, that have received much attention as cellular models of information storage in the central nervous system.
Timothy V.P. Bliss, Sam F. Cooke
doaj   +5 more sources

Do tau-synaptic long-term depression interactions in the hippocampus play a pivotal role in the progression of Alzheimer’s disease? [PDF]

open access: yesNeural Regeneration Research, 2023
Cognitive decline in Alzheimer’s disease correlates with the extent of tau pathology, in particular tau hyperphosphorylation that initially appears in the transentorhinal and related regions of the brain including the hippocampus.
Zhengtao Hu   +8 more
doaj   +2 more sources

The Intriguing Contribution of Hippocampal Long-Term Depression to Spatial Learning and Long-Term Memory [PDF]

open access: yesFrontiers in Behavioral Neuroscience, 2022
Long-term potentiation (LTP) and long-term depression (LTD) comprise the principal cellular mechanisms that fulfill established criteria for the physiological correlates of learning and memory. Traditionally LTP, that increases synaptic weights, has been
Martin Stacho, Denise Manahan-Vaughan
doaj   +2 more sources

Astrocytic p38α MAPK drives NMDA receptor-dependent long-term depression and modulates long-term memory

open access: yesNature Communications, 2019
How astrocytes influence neuronal plasticity remains unclear, as they are typically considered as modulators of core mechanisms driven by neuronal components.
Marta Navarrete   +10 more
doaj   +2 more sources

Astrocyte and neuron cooperation in long-term depression. [PDF]

open access: yesTrends Neurosci, 2021
Durkee C   +3 more
europepmc   +2 more sources

A methylation study of long-term depression risk. [PDF]

open access: yesMol Psychiatry, 2020
Clark SL   +13 more
europepmc   +2 more sources

NMDAR-dependent long-term depression is associated with increased short term plasticity through autophagy mediated loss of PSD-95. [PDF]

open access: yesNat Commun, 2021
Compans B   +16 more
europepmc   +2 more sources

Implementation of Neuro-Memristive Synapse for Long-and Short-Term Bio-Synaptic Plasticity

open access: yesSensors, 2021
In this paper, we propose a complex neuro-memristive synapse that exhibits the physiological acts of synaptic potentiation and depression of the human-brain.
Zubaer I. Mannan   +2 more
doaj   +1 more source

Peers, Gender, and Long-Term Depression [PDF]

open access: yesSSRN Electronic Journal, 2020
We provide first evidence that peer depression in adolescence affects own depression in adulthood. We use data from Add Health and an identification strategy that relies on within-school and across-cohort idiosyncratic variation in the share of own-gender peers who are depressed. We find a significant peer effect for females but not for males.
Corrado Giulietti   +2 more
openaire   +6 more sources

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