Results 11 to 20 of about 470,220 (291)
Mental Illness, 2012 This study is a follow-up of inpatients diagnosed with severe depression/melancholia between 1956 and 1969. During this period, all inpatients at the Department of Psychiatry, University Hospital, Lund, were rated on a multidimensional diagnostic ...
Lisa Crona, Louise Brådvik
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Frontiers in Cellular Neuroscience, 2019 Neuroactive estrogenic and androgenic steroids influence synaptic transmission, finely modulating synaptic plasticity in several brain regions including the hippocampus.
Alessandro Tozzi +9 more
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Stochastic Induction of Long-Term Potentiation and Long-Term Depression [PDF]
Scientific Reports, 2016 AbstractLong-term depression (LTD) and long-term potentiation (LTP) of granule-Purkinje cell synapses are persistent synaptic alterations induced by high and low rises of the intracellular calcium ion concentration ([Ca2+]), respectively. The occurrence of LTD involves the activation of a positive feedback loop formed by protein kinase C, phospholipase
Fábio M. Simões-de-Souza +2 more
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Rho Signaling in Synaptic Plasticity, Memory, and Brain Disorders
Frontiers in Cell and Developmental Biology, 2021 Memory impairments are associated with many brain disorders such as autism, Alzheimer’s disease, and depression. Forming memories involves modifications of synaptic transmission and spine morphology.
Haorui Zhang +7 more
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Long-Term Depression of mGluR1 Signaling [PDF]
Neuron, 2007 Glutamate produces both fast excitation through activation of ionotropic receptors and slower actions through metabotropic receptors (mGluRs). To date, ionotropic but not metabotropic neurotransmission has been shown to undergo long-term synaptic potentiation and depression.
Paul F. Worley +4 more
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Frontiers in Behavioral Neuroscience, 2010 Although habituation is possibly the simplest form of learning, we still do not fully understand the neurobiological basis of habituation in any organism.
Joseph eEsdin +2 more
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European Journal of Cell Biology, 2023 Dendritic spines form the postsynaptic compartment of most excitatory synapses in the vertebrate brain. Morphological changes of dendritic spines contribute to major forms of synaptic plasticity such as long-term potentiation (LTP) or depression (LTD ...
Anika Heinze, Marco B. Rust
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Repetitive transcranial magnetic stimulation in psychiatry
Annals of Indian Academy of Neurology, 2011 Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive and relatively painless tool that has been used to study various cognitive functions as well as to understand the brain-behavior relationship in normal individuals as well as in those ...
Biswa Ranjan Mishra +5 more
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Delirium, depression, and long-term cognition
International Psychogeriatrics, 2023 We examined whether preadmission history of depression is associated with less delirium/coma-free (DCF) days, worse 1-year depression severity and cognitive impairment.A health proxy reported history of depression. Separate models examined the effect of preadmission history of depression on: (a) intensive care unit (ICU) course, measured as DCF days ...
Patricia S. Andrews +9 more
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Purkinje cells translate subjective salience into readiness to act and choice performance
Cell Reports, 2021 Summary: The brain selectively allocates attention from a continuous stream of sensory input. This process is typically attributed to computations in distinct regions of the forebrain and midbrain.
Lorenzo Bina +4 more
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