Results 11 to 20 of about 525,185 (258)
Reversing cerebellar long-term depression [PDF]
The discovery of a postsynaptically expressed form of cerebellar parallel fiber–Purkinje cell long-term potentiation (LTP) raises the question whether this is the long-sought resetting mechanism for long-term depression (LTD). Extracellular monitoring of PC spikes enables stable prolonged recordings of parallel fiber–Purkinje cell synaptic
Varda, Lev-Ram +3 more
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This study is a follow-up of inpatients diagnosed with severe depression/melancholia between 1956 and 1969. During this period, all inpatients at the Department of Psychiatry, University Hospital, Lund, were rated on a multidimensional diagnostic ...
Lisa Crona, Louise Brådvik
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Rho Signaling in Synaptic Plasticity, Memory, and Brain Disorders
Memory impairments are associated with many brain disorders such as autism, Alzheimer’s disease, and depression. Forming memories involves modifications of synaptic transmission and spine morphology.
Haorui Zhang +7 more
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Neuroactive estrogenic and androgenic steroids influence synaptic transmission, finely modulating synaptic plasticity in several brain regions including the hippocampus.
Alessandro Tozzi +9 more
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Repetitive transcranial magnetic stimulation in psychiatry
Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive and relatively painless tool that has been used to study various cognitive functions as well as to understand the brain-behavior relationship in normal individuals as well as in those ...
Biswa Ranjan Mishra +5 more
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Convergent evidence for abnormal striatal synaptic plasticity in dystonia
Dystonia is a functionally disabling movement disorder characterized by abnormal movements and postures. Although substantial recent progress has been made in identifying genetic factors, the pathophysiology of the disease remains a mystery.
David A. Peterson +2 more
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Although habituation is possibly the simplest form of learning, we still do not fully understand the neurobiological basis of habituation in any organism.
Joseph eEsdin +2 more
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Intracellular processes in neurons begins when the extracellular chemical signals such as neurotransmitters, attached at specific receptors which then activates a cascade of intracellular reactions included herein are proteins GTP, second messengers ...
Shahdevi Nandar Kurniawan
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Motor cortical plasticity induced by motor learning through mental practice.
Several investigations suggest that actual and mental actions trigger similar neural substrates. Motor learning via physical practice results in long-term potentiation (LTP)-like plasticity processes, namely potentiation of M1 and a temporary occlusion ...
Laura eAvanzino +5 more
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The demise of the synapse as the locus of memory: A looming paradigm shift?
Synaptic plasticity is widely considered to be the neurobiological basis of learning and memory by neuroscientists and researchers in adjacent fields, though diverging opinions are increasingly being recognised. From the perspective of what we might call
Patrick C. Trettenbrein +1 more
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