Results 11 to 20 of about 480,748 (291)

Purkinje cells translate subjective salience into readiness to act and choice performance

open access: yesCell Reports, 2021
Summary: The brain selectively allocates attention from a continuous stream of sensory input. This process is typically attributed to computations in distinct regions of the forebrain and midbrain.
Lorenzo Bina   +4 more
doaj   +1 more source

Intelligent Diagnosis Approach for Depression Using Vocal Source Features

open access: yesTehnički Vjesnik, 2022
Depression is the most widely affecting of mental illnesses for public health concern. Although there are many treatments for depression, barriers to diagnosis still exist.
Yuan Gao, Yinan Xin, Li Zhang
doaj   +1 more source

Long-term course of severe depression: late remission and recurrence may be found in a follow-up after 38-53 years

open access: yesMental Illness, 2012
This study is a follow-up of inpatients diagnosed with severe depression/melancholia between 1956 and 1969. During this period, all inpatients at the Department of Psychiatry, University Hospital, Lund, were rated on a multidimensional diagnostic ...
Lisa Crona, Louise Brådvik
doaj   +1 more source

Bidirectional Synaptic Plasticity Is Driven by Sex Neurosteroids Targeting Estrogen and Androgen Receptors in Hippocampal CA1 Pyramidal Neurons

open access: yesFrontiers in Cellular Neuroscience, 2019
Neuroactive estrogenic and androgenic steroids influence synaptic transmission, finely modulating synaptic plasticity in several brain regions including the hippocampus.
Alessandro Tozzi   +9 more
doaj   +1 more source

Rho Signaling in Synaptic Plasticity, Memory, and Brain Disorders

open access: yesFrontiers in Cell and Developmental Biology, 2021
Memory impairments are associated with many brain disorders such as autism, Alzheimer’s disease, and depression. Forming memories involves modifications of synaptic transmission and spine morphology.
Haorui Zhang   +7 more
doaj   +1 more source

Stochastic Induction of Long-Term Potentiation and Long-Term Depression [PDF]

open access: yesScientific Reports, 2016
AbstractLong-term depression (LTD) and long-term potentiation (LTP) of granule-Purkinje cell synapses are persistent synaptic alterations induced by high and low rises of the intracellular calcium ion concentration ([Ca2+]), respectively. The occurrence of LTD involves the activation of a positive feedback loop formed by protein kinase C, phospholipase
Fábio M. Simões-de-Souza   +2 more
openaire   +3 more sources

Long-Term Depression of mGluR1 Signaling [PDF]

open access: yesNeuron, 2007
Glutamate produces both fast excitation through activation of ionotropic receptors and slower actions through metabotropic receptors (mGluRs). To date, ionotropic but not metabotropic neurotransmission has been shown to undergo long-term synaptic potentiation and depression.
Paul F. Worley   +4 more
openaire   +3 more sources

Repetitive transcranial magnetic stimulation in psychiatry

open access: yesAnnals of Indian Academy of Neurology, 2011
Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive and relatively painless tool that has been used to study various cognitive functions as well as to understand the brain-behavior relationship in normal individuals as well as in those ...
Biswa Ranjan Mishra   +5 more
doaj   +1 more source

Convergent evidence for abnormal striatal synaptic plasticity in dystonia

open access: yesNeurobiology of Disease, 2010
Dystonia is a functionally disabling movement disorder characterized by abnormal movements and postures. Although substantial recent progress has been made in identifying genetic factors, the pathophysiology of the disease remains a mystery.
David A. Peterson   +2 more
doaj   +1 more source

Delirium, depression, and long-term cognition

open access: yesInternational Psychogeriatrics, 2023
We examined whether preadmission history of depression is associated with less delirium/coma-free (DCF) days, worse 1-year depression severity and cognitive impairment.A health proxy reported history of depression. Separate models examined the effect of preadmission history of depression on: (a) intensive care unit (ICU) course, measured as DCF days ...
Patricia S. Andrews   +9 more
openaire   +3 more sources

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