Results 81 to 90 of about 4,235,672 (400)

Using digital phenotyping to capture depression symptom variability: detecting naturalistic variability in depression symptoms across one year using passively collected wearable movement and sleep data

open access: yesTranslational Psychiatry, 2023
Major Depressive Disorder (MDD) presents considerable challenges to diagnosis and management due to symptom variability across time. Only recent work has highlighted the clinical implications for interrogating depression symptom variability.
George D. Price   +4 more
doaj   +1 more source

Predictors of long-term prognosis of depression [PDF]

open access: yesCanadian Medical Association Journal, 2011
Many people with depression experience repeated episodes. Previous research into the predictors of chronic depression has focused primarily on the clinical features of the disease; however, little is known about the broader spectrum of sociodemographic and health factors inherent in its development.
Anushka Ataullahjan   +5 more
openaire   +3 more sources

miR-191 and miR-135 are required for long-lasting spine remodeling associated with synaptic long term depression

open access: yesNature Communications, 2014
Activity-dependent modification of dendritic spines, subcellular compartments accommodating postsynaptic specializations in the brain, is an important cellular mechanism for brain development, cognition and synaptic pathology of brain disorders.
Zhonghua Hu   +6 more
semanticscholar   +1 more source

A model for continuous monitoring of patients with major depression in short and long term periods [PDF]

open access: yes, 2016
The final publication is available at IOS Press through http://dx.doi.org/10.3233/THC-161289BACKGROUND AND OBJECTIVE: Major depressive disorder causes more human suffering than any other disease affecting humankind.
Bagherpour, Solmaz   +4 more
core   +2 more sources

Home‐Based Tele‐tDCS in Amyotrophic Lateral Sclerosis: Feasibility, Safety, and Preliminary Efficacy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease with limited treatment options. Transcranial direct current stimulation (tDCS) shows promise as a neuromodulatory intervention in various neurological disorders, but its application in ALS, particularly in a remote, home‐based format, remains underexplored.
Sangeetha Madhavan   +6 more
wiley   +1 more source

The role of astrocytic aquaporin-4 in synaptic plasticity and learning and memory

open access: yesFrontiers in Integrative Neuroscience, 2016
Aquaporin-4 (AQP4) is the predominant water channel expressed by astrocytes in the central nervous system. AQP4 is widely expressed throughout the brain, especially at the blood-brain barrier where AQP4 is highly polarized to astrocytic foot processes ...
Jenny I. Szu, Devin K. Binder
doaj   +1 more source

Long-Term Depression of a Dopamine IPSC [PDF]

open access: yesThe Journal of Neuroscience, 2007
Two determinants of dopamine release from terminals in striatal and limbic structures are the pattern and rate of dopamine neuron firing in the ventral midbrain. This activity is regulated in part by somatodendritic release of dopamine and subsequent feedback inhibition through activation of D2receptors on dopamine neuron cell bodies and dendrites ...
Michael J. Beckstead, John T. Williams
openaire   +3 more sources

Beyond Near- and Long-Term: Towards a Clearer Account of Research Priorities in AI Ethics and Society [PDF]

open access: yesarXiv, 2020
One way of carving up the broad "AI ethics and society" research space that has emerged in recent years is to distinguish between "near-term" and "long-term" research. While such ways of breaking down the research space can be useful, we put forward several concerns about the near/long-term distinction gaining too much prominence in how research ...
arxiv  

The effect of alternative and personalized therapy in the treatment of depression in older adults living in long-term care facilities [PDF]

open access: yes, 2021
Title: The effect of alternative and personalized therapy in the treatment of depression in older adults living in long-term care facilities Background: In older adults, depression can lead to changes in memory, physical pain, fatigue, sleep disturbances,
Davis, Amber   +4 more
core   +1 more source

Threshold Values of Sleep Spindles Features in Healthy Adults Using Scalp‐EEG and Associations With Sleep Parameters

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Sleep spindles are an electrophysiological fingerprint of the sleeping human brain. They can be described in terms of duration, frequency, amplitude, and density, and vary widely according to age and sex. Spindles play a role in sleep and wake functions and are altered in several neurological and psychiatric disorders.
Julien Coelho   +8 more
wiley   +1 more source

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