Results 171 to 180 of about 3,183,091 (359)

Developmental Effect of Dark Rearing on Long-Term Potentiation (LTP) Induction in CA1 Area of Hippocampus

مجله دانشکده پزشکی اصفهان, 2013
Background: In the critical period of brain development, in addition to natural function of neurons, the environmental signals strikingly affect the brain structure and function.
Sayyed Alireza Talaei, Sayyed Mojtaba Banitaba Bidgoli, Saeideh Davari, Mahmoud Salami   +3 more
doaj  

Comprehensive Profiling of N6‐methyladnosine (m6A) Readouts Reveals Novel m6A Readers That Regulate Human Embryonic Stem Cell Differentiation

Advanced Science, EarlyView.
This research deciphers the m6A transcriptome by profiling its sites and functional readout effects: from mRNA stability, translation to alternative splicing, across five different cell types. Machine learning model identifies novel m6A‐binding proteins DDX6 and FXR2 and novel m6A reader proteins FUBP3 and L1TD1.
Zhou Huang, Rucong Liu, Zibaguli Wubulikasimu, Wanqing Zhao, Jiaqi Huang, Jiaxuan Wang, Tianyuan Zhang, Rui Fan, Wei Kong, Qinghua Cui, Yang Li, Yuan Zhou   +11 more
wiley   +1 more source

Reversal of Long-Term Potentiation-Like Plasticity Processes after Motor Learning Disrupts Skill Retention [PDF]

, 2013
Gabriela Cantarero, Ashley Lloyd, Pablo Celnik   +2 more
openalex   +1 more source

ACSL5 Regulates Glucose Metabolism and Chemotherapy Sensitivity in Colorectal Cancer Cells under Glutamine Deficiency

Advanced Science, EarlyView.
Glutamine deprivation triggers ACSL5 upregulation in tumor cells, sustaining their viability via dual metabolic rewiring programs. ACSL5 enhances glycolysis by relieving p53's inhibition of PGAM1 while also sustaining mitochondrial respiration and TCA cycle flux through promoting IDH2 dimerization.
Shuai Tian, Qiaoxia Zhang, Xuedan Sun, Rick Francis Thorne, Zeyuan Shi, Qiang Ji, Zhangran Sun, Yuanxiang Lu, Qun Zhao, Xianjun Yu, Wanglai Hu, Mian Wu   +11 more
wiley   +1 more source

Age-Dependent Enhancement of Hippocampal Long-Term Potentiation and Impairment of Spatial Learning through the Rho-Associated Kinase Pathway in Protein Tyrosine Phosphatase Receptor Type Z-Deficient Mice [PDF]

, 2005
Kazue Niisato, Akihiro Fujikawa, Shoji Komai, Takafumi Shintani, Eiji Watanabe, Gaku Sakaguchi, Goro Katsuura, Toshiya Manabe, Masaharu Noda   +8 more
openalex   +1 more source

Glutamatergic synapses are structurally and biochemically complex because of multiple plasticity processes: long-term potentiation, long-term depression, short-term potentiation and scaling

Philosophical Transactions of the Royal Society B: Biological Sciences, 2017
J. Lisman
semanticscholar   +1 more source

Subicular Astrocytes Govern Seizure‐Impaired Fear Memory

Advanced Science, EarlyView.
Astrocytes in dorsal subiculum act as a critical modulator of seizure‐associated cognitive dysfunction, operating through a Ca2+‐dependent adenosine‐linked astrocyte‐neuron signaling pathway that disrupts neuronal circuit homeostasis. This research highlights the potential of astrocyte‐targeted interventions as a therapeutic strategy, moving beyond the
Yuying Shao, Jing Xi, Yuhao Sun, Yulan Li, Zhisheng Li, Wangjialu Lu, Jialu Chen, Lin Yang, Fan Fei, Heming Cheng, Li Cheng, Cenglin Xu, Zhuo Huang, Vladimir Parpura, Yi Wang, Zhong Chen   +15 more
wiley   +1 more source

Long-term potentiation by serotonin and noradrenaline of GABA-mediated transmission on rat cerebellar Purkinje cells.

, 1996
Hiroshi Mitoma, Shiro Konishi
openalex   +1 more source

IGZO‐Based First Spike Timing Tactile Encoders and Coupling‐Enhanced Transistor Synapses for Efficient Spiking Neural Networks

Advanced Science, EarlyView.
Here, a bioinspired light‐accelerated neuromorphic system that seamlessly links tactile sensing, first‐spike‐timing (FST) encoding, and light–electric synaptic learning. Pressure stimuli trigger FST spikes in dual‐gate PDTFTs, while GaOx/IGZO hetero‐synapses exhibit enhanced memory under optical–electrical co‐activation, enabling spiking neural ...
Dan Cai, Jinyong Wang, Tianchen Zhao, Miao Shen, Yunbo Liu, Tieyi Zhang, Fangjie Zhang, Yang Wang, Yadong Jiang, Deen Gu   +9 more
wiley   +1 more source

Polyadenylation landscape of in vivo long-term potentiation in the rat brain. [PDF]

RNA
Gumińska N, Pauzin FP, Kuźniewska B, Miłek J, Wardaszka-Pianka P, Krawczyk PS, Mroczek S, Jeleń S, Pagenhart PU, Bramham CR, Dziembowski A, Dziembowska M.   +11 more
europepmc   +1 more source