Results 181 to 190 of about 81,804 (294)

Nanoshield‐Assisted Viral Gene Therapy with Induction of Non‐Apoptotic Cell Death and Durable Antitumor Immunity

Advanced Science, EarlyView.
A novel hybrid gene delivery platform combines adeno‐associated virus (AAV)‐mediated receptor‐interacting kinase 3 (RIPK3) expression with manganese dioxide‐polyethyleneimine (MnO2−PEI) nanoshield to induce necroptosis, ferroptosis, and immunogenic cell death, effectively reprogramming the tumor microenvironment.
Soo‐Hwan Lee, Yunkyeong Cho, Seunghwan Bang, Daeun Sung, Jahyun Koo, Seoyoung Kim, Youngil Koh, Hojun Kim, Hyojin Lee   +8 more
wiley   +1 more source

Cannabidiolic Acid Rescues Deficits in Hippocampal Long-Term Potentiation in Models of Alzheimer's Disease: An Electrophysiological and Proteomic Analysis. [PDF]

Int J Mol Sci
Gil B, Sullivan M, Scaife C, Glennon JC, Herron C.   +4 more
europepmc   +1 more source

Ryanodine produces a low frequency stimulation‐induced NMDA receptor‐independent long‐term potentiation in the rat dentate gyrus in vitro.

, 1996
Y Wang, Jiaxiang Wu, Michael J. Rowan, Roger Anwyl   +3 more
openalex   +2 more sources

The selective neuronal NO synthase inhibitor 7-nitro-indazole blocks both long-term potentiation and depotentiation of field EPSPs in rat hippocampal CA1 in vivo [PDF]

, 1996
Chris Doyle, Christian Hölscher, MJ Rowan, Roger Anwyl   +3 more
openalex   +1 more source

Morphine Tolerance Gated through EZH2‐Mediated Suppression of Trpc5 in Spinal GABAergic Interneurons in Male Mice

Advanced Science, EarlyView.
Chronic morphine suppresses Trpc5 in spinal GABAergic interneurons via EZH2‐mediated histone modification, reducing Ca2+ influx and GABA release. TRPC5 activation enhances morphine analgesia, while EZH2 inhibition restores efficacy and reverses tolerance.
Li Wan, Mengyao Zhang, Haiyue Guo, Yan Xu, Chenjie Xu, Fan Hu, Yinbing Pan, Xian Wang, Wentao Liu, Chun‐Yi Jiang   +9 more
wiley   +1 more source

Long-term potentiation and long-term depression are both impaired after<i>in vitro</i>stretch injury measured with stretchable microelectrode arrays. [PDF]

Biomed Phys Eng Express
Dwyer MKR, Polsfuss I, Herbert K, Varghese N, Morrison B.   +4 more
europepmc   +1 more source

Long-term potentiation involves increases in the probability of neurotransmitter release

, 1997
Paul E. Schulz
openalex   +1 more source

Selective Alteration of Long-Term Potentiation-Induced Transcriptional Response in Hippocampus of Aged, Memory-Impaired Rats [PDF]

, 1997
Anthony A. Lanahan, Gregory L. Lyford, Gail S. Stevenson, Paul F. Worley, Carol A. Barnes   +4 more
openalex   +1 more source

Phospholipid Remodeling and Tri‐Layer Membrane Reconstruction Mediate Cognitive Effects of Humanized Milk Fat Globules in Neonatal Rats

Advanced Science, EarlyView.
Humanized milk fat globules (MFG) mimic the native composition and structure of human milk, achieved through remodeling of milk fat globule membrane phospholipid composition and reconstruction of the tri‐layer membrane structure. These humanized MFG exhibit improved structural stability and digestibility, and enhance neurodevelopment in formula‐fed rat
Shaolei Wang, Fengzhi Qiao, Jian He, Jianxin Fu, Tongjie Liu, Huaxi Yi, Qinghai Sheng, Lanwei Zhang, Kai Lin   +8 more
wiley   +1 more source

DYRK1A Up-Regulation Specifically Impairs a Presynaptic Form of Long-Term Potentiation. [PDF]

Life (Basel)
Lepagnol-Bestel AM, Haziza S, Viard J, Salin PA, Duchon A, Herault Y, Simonneau M.   +6 more
europepmc   +1 more source