Results 61 to 70 of about 3,354,348 (302)
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
EMPIRICAL STRENGTH CRITERION OF COMPOSITE MATERIALS
Empirical long-term strength criterion in terms of limit stress for constructive polymer materials considering ageing factor is found. The criterion corresponds to the type of Goldenblat - Kopnov.
O.G. OSYAEV
doaj
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Assessment of Individual Resource of High-Pressure Rotors of Nuclear Power Plants Steam Turbines
Integration of the Ukrainian energy system into the European one is a component of Ukraine's strategic goal – joining the EU. Our country has sufficiently strong and developed gas and oil transport networks, as well as electricity networks, all connected
Olha Yu. Chernousenko
doaj +1 more source
Nonlinear vibrations and long-term strength of turbine blades [PDF]
The method of a durability estimation of rotating turbomachinery blades at forced flexural-flexural-torsional vibrations is offered. The method is based on the methods of Continuous Damage Mechanics and the accurate strain analysis of the pre-twisted ...
Breslavsky, D. V. +2 more
core
Reduced energy availability: implications for bone health in physically active populations [PDF]
Purpose: The present review critically evaluates existing literature on the effects of short- and long-term low energy availability (EA) on bone metabolism and health in physically active individuals.
Dolan, E +3 more
core +1 more source
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Steam curing effect on the properties of fly ash high performance recycled aggregates concrete [PDF]
The aim of this study is to encourage the use of Recycled Concrete Aggregate (RCA) in High Performance Concrete (HPC) with fly ash. Three types of coarse RCA sourced from medium to high strength concretes were employed in 100% replacement.
Etxeberria Larrañaga, Miren +1 more
core +1 more source
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source

