Results 221 to 230 of about 72,066 (264)
Some of the next articles are maybe not open access.
Annual Review of Neuroscience, 1995
It is widely assumed that long-term changes in synaptic strength underlie information storage in the brain and, ultimately, behavioral memory. Recent years have seen a major effort to identify and analyze electrophysiological model systems in which particular patterns of neural activity give rise to such enduring changes.
D J, Linden, J A, Connor
openaire +3 more sources
It is widely assumed that long-term changes in synaptic strength underlie information storage in the brain and, ultimately, behavioral memory. Recent years have seen a major effort to identify and analyze electrophysiological model systems in which particular patterns of neural activity give rise to such enduring changes.
D J, Linden, J A, Connor
openaire +3 more sources
Long-Term Depression of Temporoammonic-CA1 Hippocampal Synaptic Transmission
Journal of Neurophysiology, 1999Long-term depression of temporoammonic-CA1 hippocampal synaptic transmission. The temporoammonic pathway, the direct projection from layer III of the entorhinal cortex to area CA1 of the hippocampus, includes both excitatory and inhibitory components that are positioned to be an important source of modulation of the hippocampal output. However, little
Dvorak-Carbone, H., Schuman, E.
openaire +3 more sources
Short- and long-term synaptic depression in rat neostriatum
Journal of Neurophysiology, 19931. We have examined plasticity at glutamatergic synapses on neurons in slices of neostriatum, a forebrain area involved in movement and cognitive function. 2. High-frequency stimulation of afferent inputs to neostriatal neurons induced depression of glutamatergic synaptic transmission. Depression could be induced using either prolonged trains or short
D M, Lovinger, E C, Tyler, A, Merritt
openaire +2 more sources
Enhanced Long-Term Synaptic Depression in an Animal Model of Depression
Biological Psychiatry, 2007A growing body of evidence suggests a disturbance of brain plasticity in major depression. In contrast to hippocampal neurogenesis, much less is known about the role of synaptic plasticity. Long-term potentiation (LTP) and long-term depression (LTD) regulate the strength of synaptic transmission and the formation of new synapses in many neural networks.
Holderbach, Roman Stefan +4 more
openaire +3 more sources
Lithium Treatment Blocks Long-Term Synaptic Depression in the Striatum
Neuron, 1993We have studied the effect of acute and chronic lithium treatment on the activity of striatal neurons recorded from corticostriatal slices. Under control conditions, tetanic stimulation of glutamatergic corticostriatal terminals caused long-term depression (LTD) of excitatory synaptic potentials.
CALABRESI, PAOLO +3 more
openaire +5 more sources
Trends in Neurosciences, 1993
In many brain areas, including the cerebellar cortex, neocortex, hippocampus, striatum and nucleus accumbens, brief activation of an excitatory pathway can produce long-term depression (LTD) of synaptic transmission. In most preparations, induction of LTD has been shown to require a minimum level of postsynaptic depolarization and a rise in the ...
A, Artola, W, Singer
openaire +2 more sources
In many brain areas, including the cerebellar cortex, neocortex, hippocampus, striatum and nucleus accumbens, brief activation of an excitatory pathway can produce long-term depression (LTD) of synaptic transmission. In most preparations, induction of LTD has been shown to require a minimum level of postsynaptic depolarization and a rise in the ...
A, Artola, W, Singer
openaire +2 more sources
Blockade of glutamate transporters facilitates cerebellar synaptic long-term depression
NeuroReport, 2009Excitatory amino acid transporters (EAATs) are believed to limit extracellular glutamate concentrations with specific roles poorly understood. At cerebellar climbing fiber-Purkinje cell synapse, EAAT4 and metabotropic glutamate receptor 1 (mGluR1) are closely expressed in surrounding postsynaptic locations, suggesting that EAAT4 may regulate mGluR1 ...
Li-Da, Su, Ying, Shen
openaire +2 more sources
Calcium as a Trigger for Cerebellar Long-Term Synaptic Depression
The Cerebellum, 2011Cerebellar long-term depression (LTD) is a form of long-term synaptic plasticity that is triggered by calcium(Ca2+) signals in the postsynaptic Purkinje cell. This Ca2+comes both from IP3-mediated release from intracellular Ca2+ stores, as well as from Ca2+ influx through voltage-gated Ca2+ channels.
Elizabeth A, Finch +2 more
openaire +2 more sources