Results 11 to 20 of about 9,101,712 (212)

Mitochondrial stress in advanced fibrosis and cirrhosis associated with chronic hepatitis B, chronic hepatitis C, or nonalcoholic steatohepatitis

Hepatology, EarlyView., 2022
Adaptive mitochondrial mechanisms allow mitochondrial resilience and prevent the worsening of fibrosis, while deregulation of these mechanisms promotes the progression from no/minimal‐mild (F0‐F2) fibrosis to advanced fibrosis and cirrhosis (F3‐F4). Abstract Background and Aims Hepatitis B virus (HBV) infection causes oxidative stress (OS) and alters ...
Dimitri Loureiro, Issam Tout, Stéphanie Narguet, Cheikh Mohamed Bed, Morgane Roinard, Ahmad Sleiman, Nathalie Boyer, Nathalie Pons‐Kerjean, Corinne Castelnau, Nathalie Giuly, Dorothy Tonui, Vassili Soumelis, Jamel El Benna, Patrick Soussan, Richard Moreau, Valérie Paradis, Abdellah Mansouri, Tarik Asselah   +17 more
wiley   +1 more source

Hypomethylation of LINE-1 repeat elements and global loss of DNA hydroxymethylation in vapers and smokers

Epigenetics, 2020
The outbreak of vaping-related severe lung injuries and deaths and the epidemic of teen vaping in the U.S. underscore the urgent need for determining the biological consequences of electronic cigarette (e-cig) use.
Andrew W. Caliri, Amanda Caceres, Stella Tommasi, Ahmad Besaratinia   +3 more
doaj   +1 more source

Characterizing Repeats in Two Whole-Genome Amplification Methods in the Reniform Nematode Genome

International Journal of Genomics, 2021
One of the major problems in the U.S. and global cotton production is the damage caused by the reniform nematode, Rotylenchulus reniformis. Amplification of DNA from single nematodes for further molecular analysis can be challenging sometimes.
S. T. Nyaku, V. R. Sripathi, K. Lawrence, G. Sharma   +3 more
doaj   +1 more source

LINE-1 hypomethylation during primary colon cancer progression. [PDF]

PLoS ONE, 2011
BACKGROUND: Methylation levels of genomic repeats such as long interspersed nucleotide elements (LINE-1) are representative of global methylation status and play an important role in maintenance of genomic stability.
Eiji Sunami, Michiel de Maat, Anna Vu, Roderick R Turner, Dave S B Hoon   +4 more
doaj   +1 more source

Bioinformatic analysis of Entamoeba histolytica SINE1 elements. [PDF]

, 2010
BACKGROUND: Invasive amoebiasis, caused by infection with the human parasite Entamoeba histolytica remains a major cause of morbidity and mortality in some less-developed countries. Genetically E.
Derek M Huntley, Ioannis Pandis, John P Ackers, Huntley Derek M, Butcher, Sarah A, Sarah A Butcher, Pandis, Ioannis, Ackers, John P, Pandis Ioannis, Ackers John P, Butcher Sarah A, Huntley, Derek M   +11 more
core   +1 more source

Distinct retroelement classes define evolutionary breakpoints demarcating sites of evolutionary novelty

BMC Genomics, 2009
Background Large-scale genome rearrangements brought about by chromosome breaks underlie numerous inherited diseases, initiate or promote many cancers and are also associated with karyotype diversification during species evolution.
Green Eric D, Carone Dawn M, Longo Mark S, O'Neill Michael J, O'Neill Rachel J   +4 more
doaj   +1 more source

A single-nucleotide-polymorphism real-time PCR assay for genotyping of mycobacterium tuberculosis complex in peri-urban Kampala [PDF]

, 2015
Accurate and high-throughput genotyping of Mycobacterium tuberculosis complex (MTBC) may be important for understanding the epidemiology and pathogenesis of tuberculosis (TB).
Eddie M. Wampande, Kathleen Eisenach, Mary Nsereko, Stavroula K. Hatzios, Wampande, Eddie M., Hatzios, Stavroula K., Mayanja, Harriet K., Mupere, Ezekiel, Gagneux, Sebastien, Eisenach, Kathleen, Joloba, Moses L., Moses L. Joloba, Achan, Beatrice, Ezekiel Mupere, Nsereko, Mary, Sebastien Gagneux, Harriet K. Mayanja, null null, Boom, W Henry, Boom, W. Henry, W Henry Boom, Tuberculosis Research Unit,, Beatrice Achan   +22 more
core   +2 more sources

The 5' untranslated region of the I factor, a long interspersed nuclear element-like retrotransposon of Drosophila melanogaster, contains an internal promoter and sequences that regulate expression [PDF]

, 1993
The I-R system of hybrid dysgenesis in Drosophila melanogaster is controlled by a long interspersed nuclear element-like retroposon, the I factor.
FINNEGAN, D J, Finnegan, David, MCLEAN, C, BUCHETON, A   +3 more
core   +1 more source

The L1Tc, Long Interspersed Nucleotide Element from Trypanosoma cruzi, Encodes a Protein with 3′-Phosphatase and 3′-Phosphodiesterase Enzymatic Activities [PDF]

Journal of Biological Chemistry, 1999
The presence of a long interspersed nucleotide element, named L1Tc, which is actively transcribed in the parasite Trypanosoma cruzi, has been recently described. The open reading frame 1 of this element encodes the NL1Tc protein, which has apurinic/apyrimidinic endonuclease activity and is probably implicated in the first stage of the transposition of ...
M, Olivares, M C, Thomas, C, Alonso, M C, López   +3 more
openaire   +2 more sources

Differential Dynamics of Transposable Elements during Long-Term Diploidization of Nicotiana Section Repandae (Solanaceae) Allopolyploid Genomes [PDF]

, 2012
PubMed ID: 23185607This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Chase Mark W., Leitch Andrew R., Andrew R. Leitch (117242), Lim, KY, Clarkson James J., Mhiri, C, James J. Clarkson (117230), Grandbastien Marie-Angèle, Parisod, C, Mark W Chase, Christian Parisod (117218), Mhiri Corinne, Corinne Mhiri (117221), Marie-Angèle Grandbastien, Clarkson, James J., Lim, K. Yoong, Christian Parisod, Clarkson, JJ, Corinne Mhiri, Marie-Angèle Grandbastien (117248), Chase, MW, Lim K. Yoong, Mark W. Chase (117236), Grandbastien, Marie Angele, K Yoong Lim, K. Yoong Lim (117224), Parisod Christian, Leitch, AR, Leitch, Andrew R., Mhiri, Corinne, Chase, Mark W., James J Clarkson, Andrew R Leitch, Grandbastien, M-A, Parisod, Christian   +34 more
core   +2 more sources