Results 31 to 40 of about 718,965 (394)

Lithium alters expression of RNAs in a type-specific manner in differentiated human neuroblastoma neuronal cultures, including specific genes involved in Alzheimer's disease. [PDF]

open access: yes, 2019
Lithium (Li) is a medication long-used to treat bipolar disorder. It is currently under investigation for multiple nervous system disorders, including Alzheimer's disease (AD).
Balaraman, Yokesh   +7 more
core   +3 more sources

Apparent non-canonical trans-splicing is generated by reverse transcriptase in vitro [PDF]

open access: yes, 2010
Trans-splicing, the in vivo joining of two RNA molecules, is well characterized in several groups of simple organisms but was long thought absent from fungi, plants and mammals.
David Tollervey   +26 more
core   +8 more sources

Downregulation of long non-coding RNA B-Raf proto-oncogene-activated non-coding RNA reverses cisplatin resistance in laryngeal squamous cell carcinoma

open access: yesArchives of Medical Science, 2019
Introduction This study was performed to explore the function of B-Raf proto-oncogene-activated non-coding RNA (BANCR) in laryngeal squamous cell carcinoma (LSCC) and cisplatin resistance.
Weiwei Han   +4 more
doaj   +1 more source

Long non-coding RNA-polycomb intimate rendezvous [PDF]

open access: yesOpen Biology, 2020
The interaction between polycomb-repressive complexes 1/2 (PRC1/2) and long non-coding RNA (lncRNA), such as the X inactive specific transcript Xist and the HOX transcript antisense RNA (HOTAIR), has been the subject of intense debate.
Andrea Cerase, Gian Gaetano Tartaglia
doaj   +1 more source

Expression of long non-coding RNA and mRNA in the hippocampus of mice with type 2 diabetes

open access: yesMolecular Medicine Reports, 2018
Long non-coding RNAs (lncRNAs) serve key roles in cell growth, development and various diseases associated with the central nervous system. However, differential expression profiles of lncRNAs in type 2 diabetes have not been reported.
L. Ci   +7 more
semanticscholar   +1 more source

Long non-coding RNAs era in liver cancer [PDF]

open access: yes, 2015
Hepatocellular carcinoma (HCC) is one of the most common malignancies leading to high mortality rates in the general population and the sixth most common cancer worldwide.
Guerrieri, Francesca
core   +1 more source

NONCODEV6: an updated database dedicated to long non-coding RNA annotation in both animals and plants

open access: yesNucleic Acids Res., 2020
NONCODE (http://www.noncode.org/) is a comprehensive database of collection and annotation of noncoding RNAs, especially long non-coding RNAs (lncRNAs) in animals.
Lianhe Zhao   +15 more
semanticscholar   +1 more source

Long non-coding RNAs in neurodevelopmental disorders [PDF]

open access: yesFrontiers in Molecular Neuroscience, 2013
Recent studies have emphasized an important role for long non-coding RNAs (lncRNA) in epigenetic regulation, development, and disease. Despite growing interest in lncRNAs, the mechanisms by which lncRNAs control cellular processes are still elusive. Improved understanding of these mechanisms is critical, because the majority of the mammalian genome is ...
Ilse Ida Gerarda Maria Van De Vondervoort   +15 more
openaire   +6 more sources

Long non‐coding RNA MALAT1 regulates retinal neurodegeneration through CREB signaling

open access: yesEMBO Molecular Medicine, 2016
The nervous and vascular systems, although functionally different, share many common regulators of function maintenance. Long non‐coding RNAs (lncRNAs) are important players in many biological processes and human disorders.
Jin Yao   +15 more
doaj   +2 more sources

Long non-coding RNA deregulation in tongue squamous cell carcinoma [PDF]

open access: yes, 2014
Background. The deregulated tumorigenic long non-coding RNA (lncRNA) has been reported in several malignancies. However, there is still no comprehensive study on tongue squamous cell carcinoma (SCC). Methods.
Chan, JYW, Gao, W, Wong, TS
core   +8 more sources

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