Results 31 to 40 of about 457,250 (297)
Long non‐coding small nucleolar RNA host genes in digestive cancers
Cancer Medicine, 2019 Although long noncoding RNAs (lncRNAs) do not have protein coding capacities, they are involved in the pathogenesis of many types of cancers, including hepatocellular carcinoma, cervical cancer, and gastric cancer. Notably, the roles of lncRNAs are vital
Huan Yang +6 more
doaj +1 more source
Respiratory Research, 2020 Background Asthma is a heterogeneous disease characterized by chronic airway inflammation. Long non-coding RNA can act as competing endogenous RNA to mRNA, and play significant role in many diseases.
Yifang Liao +5 more
doaj +1 more source
An Emerging Class of Long Non-coding RNA With Oncogenic Role Arises From the snoRNA Host Genes
Frontiers in Oncology, 2020 The small nucleolar RNA host genes (SNHGs) are a group of long non-coding RNAs, which are reported in many studies as being overexpressed in various cancers.
Alina-Andreea Zimta +5 more
semanticscholar +1 more source
PLoS ONE, 2022 Colorectal cancer (CRC) ranks the third in cancers and the second in the reasons of cancer-related death. More evidence indicates that long non-coding RNA participates in tumor initiation and progression. It’s known that cancer susceptibility candidate 9
Heping Zhang +5 more
doaj +2 more sources
Pathophysiology and Clinical Utility of Non-coding RNAs in Epilepsy
Frontiers in Molecular Neuroscience, 2017 Epilepsy is a common neurologic disorder. The underlying pathological processes include synaptic strength, inflammation, ion channels, and apoptosis. Acting as epigenetic factors, non-coding RNAs (ncRNAs) participate in the regulation of pathophysiologic
Yiye Shao +3 more
doaj +1 more source
Silencing long non-coding RNA Kcnq1ot1 alleviates pyroptosis and fibrosis in diabetic cardiomyopathy
Cell Death and Disease, 2018 Diabetes cardiomyopathy (DCM) is a critical complication of long-term chronic diabetes mellitus and is characterized by myocardial fibrosis and myocardial hypertrophy.
Fan Yang +13 more
semanticscholar +1 more source
Genome-wide analysis of long non-coding RNA expression and function in colorectal cancer
Tumor Biology, 2017 Long non-coding RNAs (lncRNAs) are widely transcribed in the genome, but their expression profile and roles in colorectal cancer are not well understood.
Fangyuan Jing +6 more
doaj +1 more source
Role of MicroRNAs and Long Non-Coding RNAs in Sarcopenia
Cells, 2022 Sarcopenia is an age-related pathological process characterized by loss of muscle mass and function, which consequently affects the quality of life of the elderly.
Jihui Lee, Hara Kang
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Nucleic Acids Research, 2016 Recently, long non-coding RNAs (lncRNAs) have been shown to have important regulatory roles in human cancer biology. In our study, we found that lncRNA CCAT1, whose expression is significantly increased and is correlated with outcomes in Esophageal ...
E. Zhang +11 more
semanticscholar +1 more source
Molecular Cancer, 2019 Gallbladder cancer is the most common biliary tract malignancy and not sensitive to chemotherapy. Autophagy is an important factor prolonging the survival of cancer cells under chemotherapeutic stress.
Qiang Cai +7 more
semanticscholar +1 more source