Results 251 to 260 of about 672,449 (294)

Carrier screening for multiple complex monogenic diseases using long-read sequencing: a population-based study of premarital couples in Shanghai. [PDF]

Hum Genomics
Hua R, Li S, Cui D, Lu Y, Li Y, Lin Y, Gao L, Lv S, Ma R, Mao A, Han X, Wang J, Wang Y.   +12 more
europepmc   +1 more source

Long-Read Sequencing for the Rapid Response to Infectious Diseases Outbreaks. [PDF]

Curr Clin Microbiol Rep
Oehler JB, Burns K, Warner J, Schmitz U.
europepmc   +1 more source

A bioinformatic survey of RNA isoform diversity and expression across 9 GTEx tissues using long-read sequencing data. [PDF]

BMC Genomics
Page ML, Aguzzoli Heberle B, Brandon JA, Wadsworth ME, Gordon LA, Nations KA, Fardo DW, Ebbert MTW.   +7 more
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Transcript Identification Through Long-Read Sequencing

2021
RNA-seq using long-read sequencing, such as nanopore and SMRT (Single Molecule, Real-Time) sequencing, enabled the identification of the full-length structure of RNA molecules. Several tools for long-read RNA-seq were developed recently. In this section, we introduce an analytical pipeline of long-read RNA-seq for isoform identification and the ...
Masahide, Seki, Miho, Oka, Liu, Xu, Ayako, Suzuki, Yutaka, Suzuki   +4 more
openaire   +2 more sources

Genomics in the long-read sequencing era

Trends in Genetics, 2023
Long-read sequencing (LRS) technologies have provided extremely powerful tools to explore genomes. While in the early years these methods suffered technical limitations, they have recently made significant progress in terms of read length, throughput, and accuracy and bioinformatics tools have strongly improved.
Erwin L, van Dijk, Delphine, Naquin, Kévin, Gorrichon, Yan, Jaszczyszyn, Rania, Ouazahrou, Claude, Thermes, Céline, Hernandez   +6 more
openaire   +2 more sources

Long-read sequencing of new Drosophila genomes

Nature Reviews Genetics, 2021
Kim et al. present a drosophilid genome resource comprising 101 de novo genome assemblies from 93 drosophilid species obtained by nanopore sequencing.
openaire   +2 more sources

Efficient short-read sequencing on long-read sequencers

2020
We present SMURF-seq, a protocol to efficiently sequence short DNA molecules on a long-read sequencer by randomly ligating them to form long molecules. Applying SMURF-seq using the highly portable and inexpensive Oxford Nanopore MinION yields up to 30 fragments per read, providing an average of 6.2 and up to 7.5 million mappable fragments per run ...
openaire   +1 more source

Assembling Plant Genomes with Long-Read Sequencing

2022
Continuous improvements in long-read sequencing allow us to tackle increasingly big and complex genomes. Here we present the principles of long-read genome assembly, taking Solanum pennellii nanopore sequencing as an example.
openaire   +2 more sources

Transcript Profiling Using Long-Read Sequencing Technologies

2018
RNA sequencing using next-generation sequencing (NGS, RNA-Seq) technologies is currently the standard approach for gene expression profiling, particularly for large-scale high-throughput studies. NGS technologies comprise short-read RNA-Seq (dominated by Illumina) and long-read RNA-Seq technologies provided by Pacific Bioscience (PacBio) and Oxford ...
Anthony, Bayega, Yu Chang, Wang, Spyros, Oikonomopoulos, Haig, Djambazian, Somayyeh, Fahiminiya, Jiannis, Ragoussis   +5 more
openaire   +2 more sources

Profiling the epigenome using long-read sequencing

Nature Genetics
The advent of single-molecule, long-read sequencing (LRS) technologies by Oxford Nanopore Technologies and Pacific Biosciences has revolutionized genomics, transcriptomics and, more recently, epigenomics research. These technologies offer distinct advantages, including the direct detection of methylated DNA and simultaneous assessment of DNA sequences ...
Tianyuan Liu, Ana Conesa
openaire   +3 more sources