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LONG-TERM POTENTIATION AND LEARNING

Annual Review of Psychology, 1996
▪ Abstract  Long-term potentiation (LTP), a relatively long-lived increase in synaptic strength, remains the most popular model for the cellular process that may underlie information storage within neural systems. The strongest arguments for a role of LTP in memory are theoretical and involve Hebb's Postulate, Marr's theory of hippocampal function, and
Brian E. Derrick   +1 more
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A model for long-term potentiation and depression

Journal of Computational Neuroscience, 1995
A computational model of long-term potentiation (LTP) and long-term depression (LTD) in the hippocampus is presented. The model assumes the existence of retrograde signals, is in good agreement with several experimental data on LTP, LTD, and their pharmacological manipulations, and shows how a simple kinetic scheme can capture the essential ...
Migliore, M, Alicata, F, Ayala, GF
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Calcium signals in long-term potentiation and long-term depression

Canadian Journal of Physiology and Pharmacology, 1999
We describe postsynaptic Ca2+signals that subserve induction of two forms of neuronal plasticity, long-term potentiation (LTP) and long-term depression (LTD), in rat hippocampal neurons. The common induction protocol for LTP, a 1-s, 50-Hz tetanus, generates Ca2+increases of about 50 µM in dendritic spines of CA1 neurons.
Satoru Otani   +3 more
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Long-Term Potentiation

2008
Long-term potentiation is an activity-dependent strengthening of synapses that is thought to underlie memory.
John E. Lisman, Johannes W. Hell
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Long-term Potentiation

Archives of Neurology, 1993
This is a very good book. Probably, it should be considered essential to the library of all those interested in the fundamental mechanisms of neuronal plasticity. One possible explanation for the quality of the book is that the editors, Michael Baudry and Joel Davis, demanded of the participants that they center their discussion around controversial ...
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Long-term potentiation in the hippocampus

Neuroscience, 1983
Long-term potentiation of field and single neuronal responses recorded in various hippocampal fields is described on the basis of author's and literary data. Most of intrahippocampal and extrinsic connections in both in vivo and in vitro hippocampal preparations show this phenomenon after one or several conditioning trains of comparatively short ...
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Long-Term Potentiation and Long-Term Depression

2018
Synaptic connections in the brain can change their strength in response to patterned activity. This ability of synapses is defined as synaptic plasticity. Long lasting forms of synaptic plasticity, long-term potentiation (LTP), and long-term depression (LTD), are thought to mediate the storage of information about stimuli or features of stimuli in a ...
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Transcriptional regulation of long-term potentiation

neurogenetics, 2016
Long-term potentiation (LTP), the persistent strengthening of synapses following high levels of stimulation, is a form of synaptic plasticity that has been studied extensively as a possible mechanism for learning and memory formation. The strengthening of the synapse that occurs during LTP requires cascades of complex molecular processes and the ...
Nicola Bliim   +3 more
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Quantal analysis and long-term potentiation

Comptes Rendus de l'Académie des Sciences - Series III - Sciences de la Vie, 1998
Quantal analysis is useful for assessing the pre- and/or post-synaptic locus of the expression of long-term tetanic potentiation with the condition, however, that the studied synaptic potentials have been evoked by single cell stimulations, as is the case with paired recordings of identified neurons.
Donald S. Faber, Henri Korn
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Long-Term Potentiation in the Motor Cortex

Science, 1989
Long-term potentiation (LTP) is a model for learning and memory processes. Tetanic stimulation of the sensory cortex produces LTP in motor cortical neurons, whereas tetanization of the ventrolateral nucleus of the thalamus, which also projects to the motor cortex, does not.
Atsushi Iriki   +3 more
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