Results 31 to 40 of about 805,319 (253)

Cardiac Arrest Induces Ischemic Long-Term Potentiation of Hippocampal CA1 Neurons That Occludes Physiological Long-Term Potentiation

Neural Plasticity, 2018
Ischemic long-term potentiation (iLTP) is a form of synaptic plasticity that occurs in acute brain slices following oxygen-glucose deprivation. In vitro, iLTP can occlude physiological LTP (pLTP) through saturation of plasticity mechanisms.
James E. Orfila, Nicole McKinnon, Myriam Moreno, Guiying Deng, Nicholas Chalmers, Robert M. Dietz, Paco S. Herson, Nidia Quillinan   +7 more
doaj   +1 more source

The α1 subunit of the GABA(A) receptor modulates fear learning and plasticity in the lateral amygdala

Frontiers in Behavioral Neuroscience, 2009
Synaptic plasticity in the amydgala is essential for emotional learning. Fear conditioning, for example, depends on changes in excitatory transmission that occur following NMDA receptor activation and AMPA receptor modification in this region. The role
Brian J Wiltgen, Brian J Wiltgen, Bill Godsil, Bill Godsil, Zechun Peng, Zechun Peng, Faysal Saab, Faysal Saab, Harry June, Michael L Van Linn, James M Cook, Carolyn Houser, Carolyn Houser, Thomas O’dell, Thomas O’dell, Gregg E Homanics, Michael Fanselow, Michael Fanselow   +17 more
doaj   +1 more source

Ovarian Hormones, Aging and Stress on Hippocampal Synaptic Plasticity [PDF]

, 2011
The ovarian steroid hormones estradiol and progesterone regulate a wide variety of non-reproductive functions in the central nervous system by interacting with molecular and cellular processes.
Foy, Michael R.
core   +2 more sources

Long-term potentiation: Peeling the onion [PDF]

Neuropharmacology, 2013
Since the discovery of long-term potentiation (LTP), thousands of papers have been published on this phenomenon. With this massive amount of information, it is often difficult, especially for someone not directly involved in the field, not to be overwhelmed.
Nicoll, Roger A, Roche, Katherine W
openaire   +5 more sources

State based model of long-term potentiation and synaptic tagging and capture [PDF]

, 2009
Recent data indicate that plasticity protocols have not only synapse-specific but also more widespread effects. In particular, in synaptic tagging and capture (STC), tagged synapses can capture plasticity-related proteins, synthesized in response to ...
A Govindarajan, A Hayer, AB Barrett, Adam B. Barrett, AJ Heynen, AM Zhabotinsky, B Hille, CCH Petersen, CM O'Carroll, D Amit, DH O'Connor, EM Izhikevich, Guy O. Billings, H Okamoto, HK Lee, HZ Shouval, HZ Shouval, JE Lisman, JR Whitlock, JW Lin, KG Reymann, Lyle J. Graham, M Graupner, M Krug, Mark C. W. van Rossum, NH Woo, P Miller, P Smolen, R Fonseca, R Fonseca, R Fonseca, Richard G. M. Morris, S Li, S Sajikumar, S Sajikumar, S Sajikumar, S Sajikumar, S Sajikumar, SJ Martin, SM Dudek, T Dunwiddie, U Frey, U Frey, U Frey, U Frey, U Staubli, W Senn, WC Abraham, WC Abraham, WS Sossin, Y Yao   +50 more
core   +4 more sources

Long Term Potentiation as a Mechanism for Learning and Memory [PDF]

Cell Journal, 2009
Since the 1970s when long term potentiation (LTP) was introduced to the scientific world;several studies have been devoted to determining whether this phenomenon is naturally abasic mechanism of learning and memory in mammalian brains. However, plenty of
Gholamali Hamidi, Sayyed Alireza Talaei Zavareh, Mahmoud Salami   +2 more
doaj  

Loss of the actin regulator cyclase-associated protein 1 (CAP1) modestly affects dendritic spine remodeling during synaptic plasticity

European Journal of Cell Biology, 2023
Dendritic spines form the postsynaptic compartment of most excitatory synapses in the vertebrate brain. Morphological changes of dendritic spines contribute to major forms of synaptic plasticity such as long-term potentiation (LTP) or depression (LTD ...
Anika Heinze, Marco B. Rust
doaj  

Temporal sensitivity of protein kinase a activation in late-phase long term potentiation. [PDF]

PLoS Computational Biology, 2010
Protein kinases play critical roles in learning and memory and in long term potentiation (LTP), a form of synaptic plasticity. The induction of late-phase LTP (L-LTP) in the CA1 region of the hippocampus requires several kinases, including CaMKII and PKA,
MyungSook Kim, Ted Huang, Ted Abel, Kim T Blackwell   +3 more
doaj   +1 more source

Long-term potentiation in frontal cortex: Role of NMDA-modulated polysynaptic excitatory pathways [PDF]

, 1989
The present study examined the role of N-methyl-D-aspartic acid (NMDA) receptors in synaptic plasticity in regular-spiking cells of rat frontal cortex. Intracortical stimulation, at levels subthreshold for elicitation of action potentials, evoked a late ...
Hablitz, John H., Sutor, Bernd
core   +1 more source

Potentiation Decay of Synapses and the Length Distributions of Synfire Chains Self-organized in Recurrent Neural Networks

, 2013
Synfire chains are thought to underlie precisely-timed sequences of spikes observed in various brain regions and across species. How they are formed is not understood. Here we analyze self-organization of synfire chains through the spike-timing dependent
Jin, Dezhe Z., Miller, Aaron
core   +1 more source