Results 101 to 110 of about 52,140 (330)

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

Detection of Mycobacterium ulcerans by the loop mediated isothermal amplification method. [PDF]

PLoS Neglected Tropical Diseases, 2012
BACKGROUND: Buruli ulcer (BU) caused by Mycobacterium ulcerans (M. ulcerans) has emerged as an important public health problem in several rural communities in sub-Saharan Africa.
Anthony Ablordey, Diana Ackon Amissah, Isaac Frimpong Aboagye, Ben Hatano, Toshio Yamazaki, Tetsutaro Sata, Koichi Ishikawa, Harutaka Katano   +7 more
doaj   +1 more source

Loop-mediated isothermal amplification (LAMP) method for rapid detection of Trypanosoma brucei rhodesiense [PDF]

, 2008
Loop-mediated isothermal amplification (LAMP) of DNA is a novel technique that rapidly amplifies target DNA under isothermal conditions. In the present study, a LAMP test was designed from the serum resistance-associated (SRA) gene of Trypanosoma brucei ...
Armstrong, T., Enyaru, J.C., Mikosza, A., Ndung'u, J.M., Njiru, Z.K., Thompson, R.C.A.   +5 more
core   +2 more sources

Development of a recombinase polymerase amplification lateral flow assay for the detection of active Trypanosoma evansi infections [PDF]

, 2020
Author summary Neglected tropical diseases (NTDs) affecting humans and/or domestic animals severely impair the socio-economic development of endemic areas. One of these diseases, animal trypanosomosis, affects livestock and is caused by the parasites of
Goossens, Julie, Li, Zeng, Magez, Stefan, Pinto Torres, Joar Esteban, Sterckx, Yann G-J, Stijlemans, Benoit   +5 more
core   +1 more source

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

Advanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad, Yasmine Ruel, Roxane Pouliot, Davide Brambilla   +3 more
wiley   +1 more source

Loop-Mediated Isothermal Amplification as a Simple Molecular Method for the Detection of Derzsy’s Disease Virus

Journal of Veterinary Research, 2013
The objective of the study was to develop a simple and rapid molecular method for the detection of GPV. Twenty seven goose parvovirus (GPV) isolates collected from geese flocks in Poland were examined.
Tarasiuk Karolina, Woźniakowski Grzegorz, Samorek-Salamonowicz Elżbieta   +2 more
doaj   +1 more source

Real-time fluorescence loop mediated isothermal amplification for the diagnosis of malaria. [PDF]

PLoS ONE, 2010
BACKGROUND: Molecular diagnostic methods can complement existing tools to improve the diagnosis of malaria. However, they require good laboratory infrastructure thereby restricting their use to reference laboratories and research studies.
Naomi W Lucchi, Allison Demas, Jothikumar Narayanan, Deborah Sumari, Abdunoor Kabanywanyi, S Patrick Kachur, John W Barnwell, Venkatachalam Udhayakumar   +7 more
doaj   +1 more source

Loop-Mediated Isothermal Amplification (LAMP) as a Promising Point-of-Care Diagnostic Strategy in Avian Virus Research

Animals, 2021
Over the years, development of molecular diagnostics has evolved significantly in the detection of pathogens within humans and their surroundings. Researchers have discovered new species and strains of viruses, while mitigating the viral infections that ...
Faiz Padzil, Abdul Razak Mariatulqabtiah, Wen Siang Tan, Kok Lian Ho, Nurulfiza Mat Isa, Han Yih Lau, Jalila Abu, Kuo-Pin Chuang   +7 more
doaj   +1 more source

Detektion des Kartoffelspindelknollen Viroids mit Hilfe der Loop Mediated Isothermal Amplification [PDF]

, 2011
PSTV ist ein hoch infektiöses Viroid, das in Kartoffeln verkleinerte und spindelähnliche Knollen verursacht. Um Ernteverlusten vorzubeugen, ist eine Detektion in frühen Infektionsstadien von großer Bedeutung.
Frohme, Marcus, Glökler, Jörn, Kadolsky, Marianne, Schulze, Katja   +3 more
core   +1 more source

Colorimetric loop-mediated isothermal amplification (LAMP) for cost-effective and quantitative detection of SARS-CoV-2: the change in color in LAMP-based assays quantitatively correlates with viral copy number.

Analytical Methods, 2021
We demonstrate a loop-mediated isothermal amplification (LAMP) method to detect and amplify SARS-CoV-2 genetic sequences using a set of in-house designed initiators that target regions encoding the N protein. We were able to detect and amplify SARS-CoV-2
E. González-González, I. M. Lara-Mayorga, I. Rodríguez-Sánchez, Y. S. Zhang, S. Martínez-Chapa, G. Santiago, M. M. Álvarez   +6 more
semanticscholar   +1 more source