Results 131 to 140 of about 38,562 (258)

Angiotensin Receptor Blockers Versus Calcium Channel Blockers for First‐Line Antihypertensive Therapy and Survival in Adults Aged 75 Years or Older

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Evidence guiding first‐line antihypertensive drug choice in adults aged 75 years or older is limited, despite widespread use of angiotensin receptor blockers (ARBs) and calcium channel blockers (CCBs) in late older age. Methods We conducted a target trial emulation using a new‐user design in a nationwide linked healthcare claims ...
Hisashi Noma, Hiroshi Sunada, Taiki Sugimoto, Ken‐Ei Sada, Futoshi Oda, Megumi Maeda, Haruhisa Fukuda   +6 more
wiley   +1 more source

Novel Intranasal Loop Diuretic

JACC: Basic to Translational Science, 2023
Benjamin Esque, Eric D. Adler, Daniel Bensimhon   +2 more
openaire   +2 more sources

Psychogenic polydipsia in dogs – a review of pathogenesis, diagnosis and treatment

Journal of Small Animal Practice, EarlyView.
Polyuria and polydipsia represent a common clinical presentation in dogs and may result from numerous disorders affecting different body systems. Compulsive water consumption is characteristic of psychogenic polydipsia, a primary polydipsia disorder rooted in neurologic, behavioural or environmental factors.
G. Pavlovsky
wiley   +1 more source

Hepatocarcinoma with tumor thrombus occupying the right atrium and portal vein in a patient with hereditary hemochromatosis and liver cirrhosis [PDF]

, 2018
We present the case of a 46-year old patient with Child-Pugh class C cirrhosis with MEDL-Score 16, and hepatocellular carcinoma invading the inferior vena cava and the right atrium.
Breaban, Iulia, Cozma, Angela, Fabian, Ovidiu, Mihailov, Anca, Muresan, Flaviu, Negrean, Vasile, Orasan, Olga Hilda, Sampelean, Dorel, Secara, Sorina Cezara, Stefan, Andreea Maria, Tarmure Sarlea, Simina, Urian, Laura   +11 more
core   +1 more source

Population Pharmacokinetics of Sildenafil in Dogs With Naturally Occurring Pulmonary Hypertension

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT The pharmacokinetics of sildenafil are ill‐defined in dogs with naturally occurring pulmonary hypertension (PH). Because the plasma concentrations of sildenafil have not been reported for dogs with this disease, this study aimed to describe the population pharmacokinetics of sildenafil in a sample of dogs with PH. Twenty client‐owned dogs with
Mariko Yata, Teresa C. DeFrancesco, John D. Bonagura, Mark G. Papich   +3 more
wiley   +1 more source

Acupuncture‐Integrated Chinese‐Western Medicine Accelerated Rehabilitation Protocol Following Acute Achilles Tendon Repair: A Prospective Cohort Study

Orthopaedic Surgery, EarlyView.
This study demonstrates that acupuncture‐integrated accelerated rehabilitation after acute Achilles tendon repair significantly reduces early postoperative pain and swelling, facilitating mobilization and enhancing objective functional recovery at 12 weeks compared to traditional and sham acupuncture protocols. ABSTRACT Objective Postoperative pain and
Gao Si, Chi Zhang, Xiuzhi Li, Yuan Cao, Zengzhen Cui, Jingying Li, Letian Wang, Yang Lv, Dong Li   +8 more
wiley   +1 more source

Neutrophil-to-Lymphocyte Ratio and Mortality in Cardiovascular Disease or Cancer

JACC: Advances
Background: Inflammation contributes to development and progression of cardiovascular disease (CVD) and cancer. Whether the neutrophil-to-lymphocyte ratio (NLR), routinely available from blood counts, predicts prognosis in the general population is ...
Moustafa I. Morsy, MSc, Jocelyn M. Friday, PhD, Jill P. Pell, MD, Jim Lewsey, PhD, Daniel F. Mackay, PhD, Ruth Dundas, MSc, Tran QB. Tran, MSc, Denise Brown, PhD, Frederick K. Ho, PhD, Claire Hastie, PhD, Michael Fleming, PhD, Claudia Geue, PhD, Alan Stevenson, BSc, Clea du Toit, MSc, Sandosh Padmanabhan, PhD, John G.F. Cleland, MD, Pasquale Maffia, PhD, Pierpaolo Pellicori, MD   +17 more
doaj   +1 more source

Sodium–glucose cotransporter 2 inhibitors for hypertension in cardiovascular–kidney–metabolic syndrome

Experimental Physiology, EarlyView.
Abstract The antihypertensive mechanism of sodium–glucose cotransporter 2 (SGLT2) inhibitors has been traditionally attributed to osmotic diuresis. However, emerging evidence reveals multifaceted mechanisms beyond diuresis, including regulation of the renin–angiotensin–aldosterone system, sympathetic nervous system suppression, ion homeostasis ...
Chunxiang Xu, Xingyu Qiu, Nan Xu, Gensheng Zhang, Enyin Lai, Liang Zhao   +5 more
wiley   +1 more source

Nonuremic Idiopathic Calciphylaxis in a Patient With Preceding Warfarin Use and Iron Infusions

Annals of Internal Medicine: Clinical Cases
Calciphylaxis is a rare and life-threatening illness characterized by microvessel occlusion due to calcification, fibro-intimal hyperplasia, and thrombosis in the subcutaneous adipose tissue and dermis.
Miranda Huebner, Aishwarya Kothapalli, Tyler Schwiesow   +2 more
doaj   +1 more source

Augmenting erythropoiesis using recombinant human erythropoietin at sea level blunts the high altitude induced increase in erythropoiesis

The Journal of Physiology, EarlyView.
Abstract figure legend Pharmacologically augmenting erythropoiesis with rEPO at sea level blunts the high altitude induced erythropoiesis. Abstract Erythropoiesis increases with high altitude (HA) acclimatization. Recombinant human erythropoietin (rEPO) induces erythropoiesis.
Roy M. Salgado, Thomas A. Mayer, Gabrielle E. W. Giersch, Billie K. Alba, David E. Barney Jr, Aaron R. Caldwell, Nisha Charkoudian, Brandon M. Roberts, Afton D. Seeley, K. Riley Connor, Andrew M. Greenfield, Adam J. Luippold, Mark L. Plamper, Jermaine A. Ward, Shauna M. Ward, Benjamin J. Ryan   +15 more
wiley   +1 more source