Results 131 to 140 of about 25,138 (263)

A double-blind randomized crossover trial of two loop diuretics in chronic kidney disease

, 2003
A double-blind randomized crossover trial of two loop diuretics in chronic kidney disease.BackgroundTorsemide has predictable absorption compared to furosemide. Thereby, torsemide results in more constant exposure to active drug.
Vasavada, Nina, Saha, Chandan, Agarwal, Rajiv, Chandan Saha, Rajiv Agarwal, Nina Vasavada   +5 more
core   +1 more source

Angiotensin Receptor Blockers Versus Calcium Channel Blockers for First‐Line Antihypertensive Therapy and Survival in Adults Aged 75 Years or Older

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Evidence guiding first‐line antihypertensive drug choice in adults aged 75 years or older is limited, despite widespread use of angiotensin receptor blockers (ARBs) and calcium channel blockers (CCBs) in late older age. Methods We conducted a target trial emulation using a new‐user design in a nationwide linked healthcare claims ...
Hisashi Noma, Hiroshi Sunada, Taiki Sugimoto, Ken‐Ei Sada, Futoshi Oda, Megumi Maeda, Haruhisa Fukuda   +6 more
wiley   +1 more source

Combination decongestion therapy in hospitalized heart failure: loop diuretics, mineralocorticoid receptor antagonists and vasopressin antagonists

, 2015
Congestion is the most common reason for admissions and readmissions for heart failure (HF). The vast majority of hospitalized HF patients appear to respond readily to loop diuretics, but available data suggest that a significant proportion are being ...
Greene, Stephen J, NODARI, Savina, Mentz, Robert J, Vaduganathan, Muthiah, Sato, Naoki, Butler, Javed, GHEORGHIADE, MIHAI, Senni, Michele   +7 more
core   +1 more source

HFrEF pharmacological treatment: diuretics

, 2018
Diuretics are an important part of the therapy for heart failure with reduced ejection fraction (HFrEF). These agents lead to amelioration of clinical symptoms and improvement in haemodynamics. There is little evidence, however, to support an association
Mariell Jessup, Rhondalyn Forde-McLean
core   +1 more source

Amiodarone‐related thyroid dysfunction and associated outcomes in patients with heart failure—A nationwide cohort study

Journal of Internal Medicine, EarlyView.
Abstract Aim Amiodarone increases the risk of thyroid dysfunction, but the prognostic significance of this complication in patients with heart failure (HF) is uncertain. This study investigates the association between amiodarone‐related thyroid dysfunction and risk of HF hospitalization or death in a nationwide cohort.
Søren Lund Kristensen, Sam Aiyad Ali, Mads Ersbøll, Jawad Haider Butt, Rasmus Rørth, Lucas Malta Westergaard, Lauge Østergaard, Finn Gustafsson, Oren Caspi, Emil Fosbøl, Lars Køber, Christian Selmer   +11 more
wiley   +1 more source

Psychogenic polydipsia in dogs – a review of pathogenesis, diagnosis and treatment

Journal of Small Animal Practice, EarlyView.
Polyuria and polydipsia represent a common clinical presentation in dogs and may result from numerous disorders affecting different body systems. Compulsive water consumption is characteristic of psychogenic polydipsia, a primary polydipsia disorder rooted in neurologic, behavioural or environmental factors.
G. Pavlovsky
wiley   +1 more source

Sodium–glucose cotransporter 2 inhibitors for hypertension in cardiovascular–kidney–metabolic syndrome

Experimental Physiology, EarlyView.
Abstract The antihypertensive mechanism of sodium–glucose cotransporter 2 (SGLT2) inhibitors has been traditionally attributed to osmotic diuresis. However, emerging evidence reveals multifaceted mechanisms beyond diuresis, including regulation of the renin–angiotensin–aldosterone system, sympathetic nervous system suppression, ion homeostasis ...
Chunxiang Xu, Xingyu Qiu, Nan Xu, Gensheng Zhang, Enyin Lai, Liang Zhao   +5 more
wiley   +1 more source

Augmenting erythropoiesis using recombinant human erythropoietin at sea level blunts the high altitude induced increase in erythropoiesis

The Journal of Physiology, EarlyView.
Abstract figure legend Pharmacologically augmenting erythropoiesis with rEPO at sea level blunts the high altitude induced erythropoiesis. Abstract Erythropoiesis increases with high altitude (HA) acclimatization. Recombinant human erythropoietin (rEPO) induces erythropoiesis.
Roy M. Salgado, Thomas A. Mayer, Gabrielle E. W. Giersch, Billie K. Alba, David E. Barney Jr, Aaron R. Caldwell, Nisha Charkoudian, Brandon M. Roberts, Afton D. Seeley, K. Riley Connor, Andrew M. Greenfield, Adam J. Luippold, Mark L. Plamper, Jermaine A. Ward, Shauna M. Ward, Benjamin J. Ryan   +15 more
wiley   +1 more source

Neutrophil-to-Lymphocyte Ratio and Mortality in Cardiovascular Disease or Cancer

JACC: Advances
Background: Inflammation contributes to development and progression of cardiovascular disease (CVD) and cancer. Whether the neutrophil-to-lymphocyte ratio (NLR), routinely available from blood counts, predicts prognosis in the general population is ...
Moustafa I. Morsy, MSc, Jocelyn M. Friday, PhD, Jill P. Pell, MD, Jim Lewsey, PhD, Daniel F. Mackay, PhD, Ruth Dundas, MSc, Tran QB. Tran, MSc, Denise Brown, PhD, Frederick K. Ho, PhD, Claire Hastie, PhD, Michael Fleming, PhD, Claudia Geue, PhD, Alan Stevenson, BSc, Clea du Toit, MSc, Sandosh Padmanabhan, PhD, John G.F. Cleland, MD, Pasquale Maffia, PhD, Pierpaolo Pellicori, MD   +17 more
doaj   +1 more source

Effect of Diuretics on Cutaneous Squamous Cell Carcinoma: Clinical and Translational Evidence

International Journal of Dermatology, EarlyView.
Kevin Sheng‐Kai Ma, Stefano Sol, Fabiana Boncimino, Serena Yun‐Chen Tsai, Bethany J. Brumbaugh, Anna Mandinova, Steven T. Chen   +6 more
wiley   +1 more source